Article
Health Care Sciences & Services
Ruby Barnard-Mayers, Hiba Kouser, Jamie A. Cohen, Katherine Tassiopoulos, Ellen C. Caniglia, Anna-Barbara Moscicki, Nicole G. Campos, Michelle R. Caunca, George R. Seage Seage, Eleanor J. Murray
Summary: Developing a causal graph is crucial in etiologic research planning. This paper presents a case study on the relationship between HPV vaccine effectiveness and HIV status, illustrating the process of designing a causal graph to inform an etiologic study.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Immunology
John D. Seeger, Kandace L. Amend, Bruce R. Turnbull, Li Zhou, Morgan A. Marks, Christine Velicer, Patricia Saddier
Summary: This study assessed the risk of new onset autoimmune conditions among males receiving the 4-valent human papillomavirus (HPV) vaccine (4vHPV), and the results showed that the incidence of autoimmune conditions among vaccinated males was similar to that among unvaccinated males.
Article
Immunology
Guangxia Yang, Zeqin Ren, Kai Wang
Summary: This study suggests that HPV infection is positively associated with the prevalence of rheumatoid arthritis (RA) in adults, while HPV immunization can reduce the prevalence of RA in adults. However, more powerful prospective studies are needed to prove these associations.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Immunology
Margaret Stanley, Elmar Joura, Glorian P. Yen, Smita Kothari, Alain Luxembourg, Alfred Saah, Anuj Walia, Gonzalo Perez, Hanane Khoury, Danielle Badgley, Darron R. Brown
Summary: Studies have shown that the nonavalent HPV vaccine induces near total seroconversion to HPV types 31, 33, 45, 52, and 58, while the bivalent and quadrivalent vaccines result in lower immune responses to non-vaccine types. Long-term data on the duration of cross-reactive immune responses beyond two years are limited, and lack of standard assays limits comparability between studies.
Article
Immunology
Eliana M. Wendland, Natalia Luiza Kops, Marina Bessel, Juliana Comerlato, Ana Goretti Kalume Maranhao, Flavia Moreno Alves Souza, Luisa Lina Villa, Gerson Fernando Mendes Pereira
Summary: The study demonstrated the effectiveness of HPV vaccination in Brazil, with higher vaccination rates among younger women and those from higher socioeconomic status. The use of quadrivalent vaccine significantly reduced HPV infection rates, particularly for HPV 6 and 16.
Article
Immunology
Ida Laake, Berit Feiring, Christine Monceyron Jonassen, John H. O. Pettersson, Torstein Gjolgali Frengen, Ingerid Orjansen Kirkeleite, Lill Trogstad
Summary: This study investigated concurrent HPV infections and associations between HPV types among 17-year-old Norwegian girls. The results showed that unvaccinated girls were more likely to be infected with multiple HPV types, and HPV33 and HPV51 were the most commonly co-infected types among both vaccinated and unvaccinated girls.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Oncology
Partha Basu, Sylla G. Malvi, Smita Joshi, Neerja Bhatla, Richard Muwonge, Eric Lucas, Yogesh Verma, Pulikkottil O. Esmy, Usha Rani Reddy Poli, Anand Shah, Eric Zomawia, Sharmila Pimple, Kasturi Jayant, Sanjay Hingmire, Aruna Chiwate, Uma Divate, Shachi Vashist, Gauravi Mishra, Radhika Jadhav, Maqsood Siddiqi, Subha Sankaran, Priya Ramesh Prabhu, Thiraviam Pillai Rameshwari Ammal Kannan, Rintu Varghese, Surendra S. Shastri, Devasena Anantharaman, Tarik Gheit, Massimo Tommasino, Catherine Sauvaget, M. Radhakrishna Pillai, Rengaswamy Sankaranarayanan
Summary: This study in India compared the efficacy of single dose HPV vaccine with two and three doses in protecting against persistent HPV 16 and 18 infection over a 10-year period. The research found that a single dose of the vaccine provided similar protection against these infections as two or three doses, which are responsible for nearly 70% of cervical cancers.
Article
Immunology
Smita Joshi, Devasena Anantharaman, Richard Muwonge, Neerja Bhatla, Gitika Panicker, Julia Butt, Usha Rani Reddy Poli, Sylla G. Malvi, Pulikkottil O. Esmy, Eric Lucas, Yogesh Verma, Anand Shah, Eric Zomawia, Sharmila Pimple, Kasturi Jayant, Sanjay Hingmire, Aruna Chiwate, Uma Divate, Shachi Vashist, Gauravi Mishra, Radhika Jadhav, Maqsood Siddiqi, Subha Sankaran, Thiraviam Pillai Rameshwari Ammal Kannan, Purnima Kartha, Surendra S. Shastri, Catherine Sauvaget, M. Radhakrishna Pillai, Tim Waterboer, Martin Mueller, Peter Sehr, Elizabeth R. Unger, Rengaswamy Sankaranarayanan, Partha Basu
Summary: The recent WHO recommendation on single-dose HPV vaccine can reduce costs, alleviate supply shortages, and simplify logistics, making it more accessible for low- and middle-income countries. This study examines the long-term immune response and compares it with unvaccinated women, showing sustained immune response in single-dose recipients at 10 years post-vaccination.
Article
Public, Environmental & Occupational Health
Chenxi Li, Thomas G. Hall, John J. Hall, Wen-Qiang He
Summary: This study assessed the effectiveness of HPV vaccine against both vaccine-type and non-vaccine-type high-risk HPV infection in the United States. The results showed that the vaccine was 58% effective against vaccine-type HPV infection and 47% effective against non-vaccine-type hrHPV infection. The study also found a significant reduction in the prevalence of diagnosed cervical cancer among vaccinated individuals.
EPIDEMIOLOGY AND INFECTION
(2023)
Article
Immunology
Nelly Mugo, Linda O. Eckert, Lydia Odero, Stephen Gakuo, Kenneth Ngure, Connie Celum, Jared M. Baeten, Ruanne V. Barnabas, Anna Wald
Summary: HIV-infected children showed a sustained antibody response following HPV vaccination. Further research is needed to determine whether HIV-infected children are protected from HPV acquisition with low levels of HPV antibodies.
Article
Immunology
Joske Hoes, Petra J. Woestenberg, Johannes A. Bogaards, Audrey J. King, Hester E. de Melker, Johannes Berkhof, Christian J. P. A. Hoebe, Marianne A. B. van der Sande, Birgit H. B. van Benthem
Summary: This study assessed trends in HPV prevalence over 8 years postvaccination among men and women in the Netherlands. Significant declines were observed in vaccine types HPV-16/18 among women, heterosexual men, and unvaccinated women, while increases were observed for certain HPV types in women and unvaccinated women. The results provide evidence of herd effects against HPV-16/18 among heterosexual men and cross-protective types, as well as herd effects against vaccine types among unvaccinated women.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Pediatrics
Yee L. Lee, Azriyanti A. Zaini, Arini N. Idris, Raja A. Abdullah, Jeanne S. L. Wong, Joyce S. S. Hong, Suhaimi Hussain, Poi G. Lim, Song H. Lim, Noor S. M. Nor, Loo L. Wu, Muhammad Y. Jalaludin
Summary: This study aimed to evaluate the prevalence of thyroid autoimmunity, the spectrum of autoimmune thyroid disease, and its association with age and karyotype among Malaysian Turner syndrome girls. The results showed that 43.8% of Turner syndrome patients had thyroid autoimmunity. Patients with isochromosome X and other X chromosomal abnormalities were more prone to thyroid autoimmunity compared to those with 45,X karyotype. The prevalence of thyroid autoimmunity increased with age, with 14.3% during adulthood. Annual screening of thyroid function is recommended for Turner syndrome patients until adulthood, with more frequent monitoring in the presence of thyroid autoimmunity.
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Michael Egbon, Tolulope Ojo, Aminu Aliyu, Zainab Shinkafi Bagudu
Summary: The study found that knowledge of HPV and cervical cancer is generally good among female students in rural Nigeria. Due to COVID-19, some students were unable to complete the vaccine dosage within the recommended timeframe. Parents who provided consent were unable to afford the vaccine costs out of pocket.
Article
Immunology
Stale Nygard, Mari Nygard, Madleen Orumaa, Bo T. Hansen
Summary: Norway's routine quadrivalent HPV vaccination for girls at 12-13 years of age has been effective in reducing the risk of AGW. However, the vaccine does not provide protection against a second episode of AGW in women who have already experienced it. Additionally, the female vaccination program also has a positive impact on unvaccinated males, leading to a gradual decrease in AGW rates.
Article
Medicine, Research & Experimental
Si-Yu Zhou, Chi Zhang, Wen-Jing Shu, Li-Ye Chong, Jun He, Zhiwei Xu, Hai-Feng Pan
Summary: This review focuses on the association between coronavirus and autoimmunity, suggesting that coronavirus may be implicated in the development and pathogenesis of autoimmune diseases. Additionally, it briefly introduces the role of coronavirus in several autoimmune diseases.
ARCHIVES OF MEDICAL RESEARCH
(2021)
