Article
Chemistry, Applied
Fan Leng, Feixiang Chen, Xulin Jiang
Summary: A rapid and effective hemorrhage control method was developed using organic solvent-free carboxymethyl chitin microspheres loaded with calcium ions and dopamine polymerization. These modified microspheres demonstrated good biocompatibility and superior hemostatic performance compared to traditional controls, significantly reducing bleeding time in a femoral artery/vein cut model. This study suggests great potential for rapid hemostasis using these modified microspheres.
CARBOHYDRATE POLYMERS
(2021)
Article
Electrochemistry
Shanshan Zhan, Caihong Xu, Jiandan Chen, Qi Xiao, Zhenzeng Zhou, Zhiyuan Xing, Chunchuan Gu, Zhengzhi Yin, Hongying Liu
Summary: Describes a new method for detecting the neurotransmitter epinephrine using an acupuncture needle as an electrochemical matrix. The sensor showed high selectivity, stability, and reproducibility, making it a promising tool for evaluating human health.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Physical
Erika Kozma, Anita Eckstein Andicsova, Alena Opalkova Siskova, Gabriele Tullii, Francesco Galeotti
Summary: This paper describes a simple and green approach to fabricate composite membranes using self-assembled polydopamine thin films and two different biopolymers at the air/water interface. It is found that the polydopamine thin films have abundant phenolic hydroxyl groups which enable in situ decoration of gold nanoparticles on the membrane surface, providing plasmonic features. Additionally, surface patterning of polydopamine layers using self-assembled templating structures is demonstrated, offering new perspectives for biocompatible functional membranes with tunable optical and spectroscopic properties. Finally, it is demonstrated that the obtained functional surfaces are promising tools for fabricating SERS substrates.
APPLIED SURFACE SCIENCE
(2022)
Article
Nanoscience & Nanotechnology
Monica A. Gordillo, Paola A. Benavides, Kaikai Ma, Sourav Saha
Summary: This study successfully transformed permanently porous but electrically insulating MOFs into electrically conducting materials by reducing gold ions to prepare highly conductive composites, which retained porosity and surface area while significantly enhancing conductivity.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Analytical
Mansi Chaturvedi, Monika Patel, Neha Bisht, Maumita Das Mukherjee, Archana Tiwari, D. P. Mondal, Avanish Kumar Srivastava, Neeraj Dwivedi, Chetna Dhand
Summary: Tuberculosis (TB) is a devastating human illness and early diagnosis is crucial. This study proposes an electrochemical biosensor based on a ternary nanocomposite for highly sensitive and selective MTB detection. The sensor showed high sensitivity and stability, and provides a unique strategy for early MTB diagnosis. The electrochemical platform has potential for detecting various infectious pathogens and biomarkers.
Article
Biotechnology & Applied Microbiology
Xiaotong Lou, Yuanyuan Hu, Hong Zhang, Jia Liu, Yin Zhao
Summary: The study suggests that a polydopamine-based nanoplatform can protect retina ganglion cells from oxidative damage, reduce inflammatory response, maintain retinal function, and potentially improve cell survival by altering gene expression through transcriptome analysis. Additionally, the nanoplatform can deliver neuroprotective drugs to synergistically promote cell survival and axon regeneration.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Spectroscopy
Mengyuan Wang, Yinzhou Yan, Yanlin Mi, Yijian Jiang
Summary: In this study, a facile flexible microsphere-coupled SERS (McSERS) substrate was developed to enhance Raman scattering. The substrate exhibited outstanding durability and compatibility, and the limit of detection was significantly improved.
JOURNAL OF RAMAN SPECTROSCOPY
(2022)
Article
Materials Science, Biomaterials
Mi So Lee, Yeonju Park, Song Rae Kim, Young Mee Jung, Hyuk Sang Yoo
Summary: The therapeutic efficacy of nanoparticles can be improved by using dual near-infrared light to enhance the release of photosensitizers. In this study, gold nanoparticles were surface-engineered and irradiated with dual NIR light to increase the liberation of chlorin-e6, resulting in enhanced anticancer effects both in vitro and in vivo.
BIOMATERIALS ADVANCES
(2022)
Article
Chemistry, Applied
Yunfeng Wan, Wenjie Yu, Jiami Li, Na Peng, Xiao Ding, Yanlong Wang, Tao Zou, Yang Cheng, Yi Liu
Summary: The use of tumor-targeted and microenvironment-responsive nanocarriers (TRN) can effectively address the issues of poor distribution and systemic side effects associated with cytokines, demonstrating significant anti-tumor efficacy in mice models.
CARBOHYDRATE POLYMERS
(2021)
Article
Nanoscience & Nanotechnology
Samir V. Jenkins, Seunghyun Jung, Azemat Jamshidi-Parsian, Michael J. Borrelli, Ruud P. M. Dings, Robert J. Griffin
Summary: This study demonstrates the influence of morphology and concentration of gold nanomaterials on radiation enhancement, providing a potential method to differentiate intra- and extracellular functionalities of gold nanomedicine treatment strategies. It also offers insights for the rational development of gold nanomaterial-based radiosensitizers for clinical use.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Pharmacology & Pharmacy
Chun-Ping Liu, Zi-De Chen, Zi-Yan Ye, Dong-Yue He, Yue Dang, Zhe-Wei Li, Lei Wang, Miao Ren, Zhi-Jin Fan, Hong-Xing Liu
Summary: Prostatitis is a common disease in adult males with poor treatment response and easy recurrence, affecting quality of life. Nanomaterials have been widely used in the diagnosis and treatment of various infectious diseases, offering potential in the diagnosis and treatment of prostatitis.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Chemistry, Inorganic & Nuclear
Malvika Shukla, Nidhi Vijay Verma, Zinia Mohanta, Shubhita Tripathi, Alok Pandya
Summary: Prussian blue nanoparticles (PBNPs) are a stable, safe, and biocompatible nanomaterial that can be synthesized into different nanostructures using simple methods. They have potential applications in drug delivery, imaging, sensing, as well as significant impacts in energy storage and water pollution control.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Nanoscience & Nanotechnology
Chloe Trayford, Darragh Crosbie, Timo Rademakers, Clemens van Blitterswijk, Rudy Nuijts, Stefano Ferrari, Pamela Habibovic, Vanessa LaPointe, Mor Dickman, Sabine van Rijt
Summary: Stem cell (SC)-based therapies have the potential to revolutionize therapeutics by enhancing the body's natural repair processes. Researchers have developed a new nanoparticle, AuMS, which can be used to trace and monitor the biodistribution and function of SCs in vivo, with the ability for multimodal imaging and simultaneous detection of reactive oxygen species (ROS).
ACS APPLIED NANO MATERIALS
(2022)
Article
Cell Biology
Samantha M. Richter, Lilyanna C. Massman, Dennis J. Stuehr, Elizabeth A. Sweeny
Summary: NADPH oxidase 5 (NOX5) is a transmembrane oxidative signaling enzyme that produces superoxide in response to intracellular calcium flux. It is involved in physiological processes and human disease, but its signaling pathways and targets of oxidative modifications remain poorly understood. This study demonstrates that NOX5 and actin interact in the cell and modulate each other's activity. Changes in actin dynamics affect NOX5 superoxide production, and NOX5 oxidatively modifies actin. Knockdown of NOX5 impairs cell migration. These findings reveal an important link between actin dynamics and oxidative signaling through NOX5.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Engineering, Chemical
Sayiter Yildiz, Gamze Topal Canbaz, Savas Kaya, Mikhail M. Maslov
Summary: The oxidative degradation of Reactive Black 5 (RB5) in aqueous solution was studied using different Fenton processes. Efficient dye degradation was observed under optimal conditions for all processes. The sono Fenton process (S-FP) showed faster degradation compared to the other processes. DFT calculations supported the experimental observations and provided insights into the chemical reactivities of the dye systems.
CHEMICAL ENGINEERING & TECHNOLOGY
(2023)
Article
Chemistry, Applied
Qi Li, Yuehan Wu, Mohd Shabbir, Ying Pei, Hongshan Liang, Jing Li, Yijie Chen, Yan Li, Bin Li, Xiaogang Luo, Shilin Liu
Summary: O/W Pickering emulsions containing oil phase with different volume fractions were prepared using bacterial cellulose nanofibrils (BCNFs) alone. The emulsions exhibited excellent physical stability and low coalescence rate, with droplet size varying from 32 to 91 μm. Increasing particle contents decreased droplet size and enhanced emulsion stability.
Article
Agriculture, Multidisciplinary
Yan Hu, Fei Liu, Junxiao Pang, David Julian McClements, Zhiqin Zhou, Bin Li, Yan Li
Summary: The research showed that encapsulating tangeretin in emulsions can enhance its oral bioavailability, with the addition of HPMC having the most significant effect.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Microbiology
Yi Li, Runan Zhao, Yan Li, Zhiqin Zhou
Summary: A nanoemulsion containing limonene was prepared to combat citrus blue mold caused by Penicillium italicum. The nanoemulsion disrupted the integrity of the pathogenic fungus's cell membrane and inhibited its ability to infect citrus fruits, showing promising antifungal activity.
Article
Chemistry, Applied
Yuxing Gao, Yujie Lei, Yuehan Wu, Hongshan Liang, Jing Li, Ying Pei, Yan Li, Bin Li, Xiaogang Luo, Shilin Liu
Summary: The study successfully fabricated stable food-grade water-in-oil emulsions using a facial method at 20 degrees C, with long-term stability and no phase separation. Beeswax was utilized as a stabilizer in the system, regulating the beeswax content to produce emulsions with a droplet diameter of around 9 μm. These surfactant-free emulsions show great potential applications in the food, pharmaceutical, and feed industries.
Article
Chemistry, Applied
Xingzhong Zhang, Yujie Lei, Xiaogang Luo, Yixiang Wang, Yan Li, Bin Li, Shilin Liu
Summary: The addition of TOBC can reduce the surface hydrophobicity of SPI at pH 2-9 by partially hindering SPI unfolding, leading to decreased formation of unordered structure. Around the isoelectric point (pH 4.5), the presence of TOBC improves the interfacial adsorption property of SPI with increased balanced interfacial surface pressure (pi) and diffusion rate constant (K-diff) values, while the viscoelastic modulus shows no significant difference. Emulsions stabilized with SPI/TOBC complexes at pH 4-5 exhibit uniform droplets distributions and smaller sizes (<20 μm), providing practical applications in the food industry.
FOOD HYDROCOLLOIDS
(2021)
Article
Food Science & Technology
Huanhuan Cui, Qihang Liu, David Julian McClements, Bin Li, Shilin Liu, Yan Li
Summary: The study found that incorporating cinnamaldehyde improved the resistance of whey protein isolate-stabilized emulsions to aggregation under high ionic strengths and gastric conditions, keeping them stable in the presence of high salt levels and simulated gastric fluids.
Article
Chemistry, Applied
Runan Zhao, Weiting Fu, Yijie Chen, Bin Li, Shilin Liu, Yan Li
Summary: The study investigated the effect of CA on WPI, showing that the WPI/CA complex can act as a stabilizer to form emulsions and emulsion gels for better protection and enhanced bioaccessibility of beta-carotene. The findings provide insights into developing new multifunctional food ingredients and improving protein modification in food systems.
Article
Chemistry, Applied
Yilan Wu, Xingzhong Zhang, Dan Qiu, Ying Pei, Yan Li, Bin Li, Shilin Liu
Summary: This study investigated the effect of surface charge density of bacterial cellulose nanofibrils on the rheological characteristics of O/W Pickering emulsions. It was found that higher charge density resulted in increased viscosity and elasticity of the emulsions. pH and ionic strength also influenced the rheological properties, with lower pH leading to higher viscosity and higher pH resulting in lower viscosity.
FOOD HYDROCOLLOIDS
(2021)
Article
Food Science & Technology
Runan Zhao, Yu Zhang, Huanle Chen, Rong Song, Yan Li
Summary: A green chitosan-based coating was prepared by incorporating chitosan-stabilized eugenol emulsions into chitosan solution. The coating significantly improved the performance of chitosan, including anti-corrosion, UV-light resistance, and water vapor permeability. It also extended the shelf-life of fresh meat.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Food Science & Technology
Rongxi Fang, Hongshan Liang, Jing Li, Yijie Chen, Xiaogang Luo, Yan Li, Bin Li, Shilin Liu
Summary: This study developed a novel encapsulation system for producing astaxanthin (AXT)-loaded microcapsules using emulsion solvent evaporation and spray-dried methods. The resulting microcapsules exhibited excellent physical stability and potential applications for AXT.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Bing Cui, Yingyi Mao, Hongshan Liang, Yan Li, Jing Li, Shuxin Ye, Wenxin Chen, Bin Li
Summary: This study presents a method to fabricate an analogue of pork backfat using a combination of emulsion and gel. By using soybean protein isolate and curdlan, an emulsion gel was prepared and its microstructures, rheology properties, water holding capacity, and freeze-thawing stability were investigated. The results showed that the emulsion gel was thermal irreversible and the oil content significantly affected its water holding capacity and freeze-thawing stability. Compared with pork backfat, the emulsion gel with 10 wt% oil content exhibited no significant differences in hardness, chewiness, springiness, and gel strength.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Qian Shen, Ting Xiong, Jun Dai, Xi Chen, Ling Wang, Yan Li, Jing Li, Bin Li, Yijie Chen
Summary: The alkali pH-shifting treatment improved the emulsifying capacity of pea protein isolates (PPI). This study further investigated the mechanism by determining the relative quantities and types of inter-facial adsorbed proteins through quantitative proteomic. The results showed that the pH 10-shifting treatment increased the relative quantities of legumins and albumins at the oil-water interface, while the relative abundances of vicilins decreased. These findings contribute to the potential development of theory of plant protein stabilized emulsions.
FOOD HYDROCOLLOIDS
(2022)
Article
Food Science & Technology
Yingzhu Zhang, Jinqi Xu, Cuie Tang, Yan Li
Summary: The concentration effects of fatty acid glycerides on the crystallization behavior and physical properties of oleogels were investigated. Saturated fatty acid glycerides (GMS, GML, GMC) formed solid-like and thermally reversible oleogels, while a higher amount of unsaturated fatty acid glycerides (GMO, GDO) were needed. The oleogels based on GMS and GMC had higher crystallinity, resulting in higher thermal stability and better mechanical properties than GML-based ones.
Article
Chemistry, Applied
Chunxiang Zhang, Yuxing Gao, Yilan Wu, Zhiliang Zheng, Yunxiao Xie, Yan Li, Bin Li, Ying Pei, Shilin Liu
Summary: Oil-in-water-in-oil (O/W/O) multiple emulsions were fabricated using carboxymethyl chitosan to stabilize the O/W emulsion as the inner dispersed phase and beeswax as the external oil phase. The study investigated the effects of beeswax content and volume fraction of the inner O/W emulsion on the morphology, stability, and rheological properties of the O/W/O multiple emulsions. Increasing the beeswax content improved the stability and viscosity of the O/W/O multiple emulsions.
FOOD HYDROCOLLOIDS
(2023)
Article
Biochemistry & Molecular Biology
Yingzhu Zhang, Ying Yang, Yingyi Mao, Yanrong Zhao, Xiang Li, Junjie Hu, Yan Li
Summary: This study investigates the effects of polar lipids (MDG and PL) on the bioaccessibility of lipophilic nutrients using a protein-based emulsion model system. The results show that the incorporation of MDG/PL benefits the dissolution and stabilization of lipophilic nutrients, improving their bioaccessibility. The use of MDG/PL also modifies the construction of the emulsion surface and decreases the interfacial tension. In vitro and cell culture experiments further demonstrate the effectiveness of MDG/PL in improving the absorption of lipophilic nutrients.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
