The appearance of phagocytic microglia in the postnatal brain of Niemann Pick type C mice is developmentally regulated and underscores shortfalls in fine odor discrimination

The Cerebellum in Niemann-Pick C1 Disease: Mouse Versus Man

(2022) Maria Teresa Fiorenza et al.   CEREBELLUM

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

(2021) Alessio Colombo et al.   Nature Communications

Identification of Novel Pathways Associated with Patterned Cerebellar Purkinje Neuron Degeneration in Niemann-Pick Disease, Type C1

(2020) Kyle B. Martin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann–Pick disease type C

(2020) Bridget R. Boyle et al.   DEVELOPMENT

A mechanical perspective on phagocytic cup formation

(2020) Daan Vorselen et al.   CURRENT OPINION IN CELL BIOLOGY

Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease

(2020) Amanda McQuade et al.   Nature Communications

Microglial ontogeny, diversity and neurodevelopmental functions

(2020) Morgane Sonia Thion et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Ponceau S waste: Ponceau S staining for total protein normalization

(2019) Hannah Sander et al.   ANALYTICAL BIOCHEMISTRY

Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability

(2019) Oscar Vivas et al.   Cell Reports

Decreased neural stem cell proliferation and olfaction in mouse models of Niemann–Pick C1 disease and the response to hydroxypropyl-β-cyclodextrin

(2019) Jessica Dragotto et al.   JOURNAL OF APPLIED GENETICS

Development and Sensory Experience Dependent Regulation of Microglia in Barrel Cortex

(2019) John Kalambogias et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Microglial regional heterogeneity and its role in the brain

(2019) Yun-Long Tan et al.   MOLECULAR PSYCHIATRY

The endocannabinoid system is affected by cholesterol dyshomeostasis: Insights from a murine model of Niemann Pick type C disease

(2019) Sergio Oddi et al.   NEUROBIOLOGY OF DISEASE

Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C

(2019) Larisa Kavetsky et al.   Scientific Reports

Alteration of GABAergic Input Precedes Neurodegeneration of Cerebellar Purkinje Cells of NPC1-Deficient Mice

(2019) Michael Rabenstein et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cerebellar microglia are dynamically unique and survey Purkinje neurons in vivo

(2018) Rianne D. Stowell et al.   Developmental Neurobiology

Microglia activation in Niemann–Pick disease, type C1 is amendable to therapeutic intervention

(2018) Antony Cougnoux et al.   HUMAN MOLECULAR GENETICS

Microglial involvement in the development of olfactory dysfunction

(2018) Yoojin Seo et al.   Journal of Veterinary Science

Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum

(2018) Hisako Nakayama et al.   Nature Communications

Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy

(2018) Xiaofeng Zhao et al.   Cell Reports

Bidirectional Microglia–Neuron Communication in Health and Disease

(2018) Zsuzsanna Szepesi et al.   Frontiers in Cellular Neuroscience

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

(2018) Qingyun Li et al.   NEURON

Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease

(2017) Sonia Canterini et al.   HUMAN MOLECULAR GENETICS

Primary cilium alterations and expression changes of Patched1 proteins in niemann-pick type C disease

(2017) Patrizia Formichi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures

(2017) Christopher J. Bohlen et al.   NEURON

Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex

(2017) Brian M. Castellano et al.   SCIENCE

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

Developmental delay in motor skill acquisition in Niemann-Pick C1 mice reveals abnormal cerebellar morphogenesis

(2016) Paola Caporali et al.   Acta Neuropathologica Communications

Effects of Microglia on Neurogenesis

(2015) Kaoru Sato   GLIA

TREM2 in CNS homeostasis and neurodegenerative disease

(2015) Meghan M. Painter et al.   Molecular Neurodegeneration

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

Testing for Odor Discrimination and Habituation in Mice

(2015) Erin P. Arbuckle et al.   Jove-Journal of Visualized Experiments

Excessive microglial activation aggravates olfactory dysfunction by impeding the survival of newborn neurons in the olfactory bulb of Niemann–Pick disease type C1 mice

(2014) Yoojin Seo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Shh-proteoglycan interactions regulate maturation of olfactory glomerular circuitry

(2014) Laura Persson et al.   Developmental Neurobiology

Complex lipid trafficking in Niemann-Pick disease type C

(2014) Marie T. Vanier   JOURNAL OF INHERITED METABOLIC DISEASE

A marked paucity of granule cells in the developing cerebellum of the Npc1−/− mouse is corrected by a single injection of hydroxypropyl-β-cyclodextrin

(2014) S. Nusca et al.   NEUROBIOLOGY OF DISEASE

Olfactory Deficits in Niemann-Pick Type C1 (NPC1) Disease

(2014) Marina Hovakimyan et al.   PLoS One

Human and mouse neuroinflammation markers in Niemann-Pick disease, type C1

(2013) Stephanie M. Cologna et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis

(2013) Amanda Sierra et al.   Frontiers in Cellular Neuroscience

Hyposmia and cognitive impairment in Gaucher disease patients and carriers

(2012) Alisdair McNeill et al.   MOVEMENT DISORDERS

A novel mouse model of Niemann–Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations

(2011) Robert A. Maue et al.   HUMAN MOLECULAR GENETICS

Early glial activation, synaptic changes and axonal pathology in the thalamocortical system of Niemann–Pick type C1 mice

(2011) Sarah N.R. Pressey et al.   NEUROBIOLOGY OF DISEASE

Linking Local Circuit Inhibition to Olfactory Behavior: A Critical Role for Granule Cells in Olfactory Discrimination

(2010) Ben W. Strowbridge   NEURON

Synaptic Inhibition in the Olfactory Bulb Accelerates Odor Discrimination in Mice

(2010) Nixon M. Abraham et al.   NEURON

Neuronal Apoptosis in the Developing Cerebellum

(2010) X.-S. Cheng et al.   ANATOMIA HISTOLOGIA EMBRYOLOGIA

Development of Cerebellar GABAergic Interneurons: Origin and Shaping of the “Minibrain” Local Connections

(2008) Ketty Leto et al.   CEREBELLUM

Correlation between olfactory bulb volume and olfactory function

(2008) D. Buschhüter et al.   NEUROIMAGE

Chemoattractive Activity of Sonic Hedgehog in the Adult Subventricular Zone Modulates the Number of Neural Precursors Reaching the Olfactory Bulb

(2008) Elodie Angot et al.   STEM CELLS