CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes

Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration

(2016) Russell D. Berg et al.   CELL

Isolation and Characterization of Salmonid CD4+T Cells

(2016) Kevin Maisey et al.   JOURNAL OF IMMUNOLOGY

Novel Teleost CD4-Bearing Cell Populations Provide Insights into the Evolutionary Origins and Primordial Roles of CD4+Lymphocytes and CD4+Macrophages

(2016) Fumio Takizawa et al.   JOURNAL OF IMMUNOLOGY

Polarization of immune responses in fish: The ‘macrophages first’ point of view

(2016) Geert F. Wiegertjes et al.   MOLECULAR IMMUNOLOGY

Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

(2016) Qin Tang et al.   Nature Communications

First in-depth analysis of the novel Th2-type cytokines in salmonid fish reveals distinct patterns of expression and modulation but overlapping bioactivities

(2016) Tiehui Wang et al.   Oncotarget

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells

(2016) Iain C. Macaulay et al.   Cell Reports

Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection

(2016) Aleksandra Bojarczuk et al.   Scientific Reports

Regulation of human helper T cell subset differentiation by cytokines

(2015) Nathalie Schmitt et al.   CURRENT OPINION IN IMMUNOLOGY

The mast cell plays a central role in the immune system of teleost fish

(2015) Alessandra Sfacteria et al.   MOLECULAR IMMUNOLOGY

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Identification of polarized macrophage subsets in zebrafish

(2015) Mai Nguyen-Chi et al.   eLife

First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio)

(2015) Sohye Yoon et al.   PLoS One

Evidence for Peroxidase Activity in Caralluma umbellata

(2014) Raghu Ram Achar et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

T cell transcripts and T cell activities in the gills of the teleost fish sea bass (Dicentrarchus labrax)

(2014) N. Nuñez Ortiz et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes

(2014) V. Briolat et al.   JOURNAL OF IMMUNOLOGY

CD4 Ligation on Human Blood Monocytes Triggers Macrophage Differentiation and Enhances HIV Infection

(2014) A. Zhen et al.   JOURNAL OF VIROLOGY

Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms

(2014) Rob Patro et al.   NATURE BIOTECHNOLOGY

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Optimized cell transplantation using adult rag2 mutant zebrafish

(2014) Qin Tang et al.   NATURE METHODS

Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress–Induced Inflammation

(2014) Sergio Candel et al.   PLOS BIOLOGY

Tailored Immune Responses: Novel Effector Helper T Cell Subsets in Protective Immunity

(2014) Ervin E. Kara et al.   PLoS Pathogens

Adequate Th2-Type Response Associates with Restricted Bacterial Growth in Latent Mycobacterial Infection of Zebrafish

(2014) Milka Marjut Hammarén et al.   PLoS Pathogens

Regulatory T cell subsets in human cancer: are they regulating for or against tumor progression?

(2013) Theresa L. Whiteside   CANCER IMMUNOLOGY IMMUNOTHERAPY

Antiviral functions of CD8+ cytotoxic T cells in teleost fish

(2013) Tomonori Somamoto et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Helper function of CD4+ lymphocytes in antiviral immunity in ginbuna crucian carp, Carassius auratus langsdorfii

(2013) Tomonori Somamoto et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Teleost T and NK cell immunity

(2013) Uwe Fischer et al.   FISH & SHELLFISH IMMUNOLOGY

The cytokine networks of adaptive immunity in fish

(2013) Tiehui Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Role of CD4+ and CD8α+ T cells in protective immunity against Edwardsiella tarda infection of ginbuna crucian carp, Carassius auratus langsdorfii

(2013) Masatoshi Yamasaki et al.   FISH & SHELLFISH IMMUNOLOGY

Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II–restricted cytotoxic T lymphocytes

(2013) Daniel Mucida et al.   NATURE IMMUNOLOGY

Fishing for mammalian paradigms in the teleost immune system

(2013) J Oriol Sunyer   NATURE IMMUNOLOGY

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Accounting for technical noise in single-cell RNA-seq experiments

(2013) Philip Brennecke et al.   NATURE METHODS

Cytokine Gene Expression in CD4 Positive Cells of the Japanese Pufferfish, Takifugu rubripes

(2013) Tomoya Kono et al.   PLoS One

Controlling the frontier: Regulatory T-cells and intestinal homeostasis

(2013) Julia Bollrath et al.   SEMINARS IN IMMUNOLOGY

Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance

(2012) Angelina M. Bilate et al.   Annual Review of Immunology

Evolution of Vertebrate Immunity

(2012) Thomas Boehm   CURRENT BIOLOGY

Clonal growth of carp (Cyprinus carpio) T cells in vitro: Long-term proliferation of Th2-like cells

(2012) Takuya Yamaguchi et al.   FISH & SHELLFISH IMMUNOLOGY

Essential Role of IL-4 and IL-4R  Interaction in Adaptive Immunity of Zebrafish: Insight into the Origin of Th2-like Regulatory Mechanism in Ancient Vertebrates

(2012) L.-y. Zhu et al.   JOURNAL OF IMMUNOLOGY

New Paradigms in Type 2 Immunity

(2012) B. Pulendran et al.   SCIENCE

Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms

(2011) Carlos R. García-Alonso et al.   ANNALS OF OPERATIONS RESEARCH

Characterization of the mononuclear phagocyte system in zebrafish

(2011) V. Wittamer et al.   BLOOD

Rapid BAC selection for tol2-mediated transgenesis in zebrafish

(2011) J. Bussmann et al.   DEVELOPMENT

Fish T cells: Recent advances through genomics

(2011) Kerry J. Laing et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Constitutive high expression of interleukin-4/13A and GATA-3 in gill and skin of salmonid fishes suggests that these tissues form Th2-skewed immune environments

(2011) Fumio Takizawa et al.   MOLECULAR IMMUNOLOGY

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

(2011) Craig J. Ceol et al.   NATURE

Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants

(2010) K. M. Balla et al.   BLOOD

Sequence and expression analysis of two T helper master transcription factors, T-bet and GATA3, in rainbow trout Oncorhynchus mykiss and analysis of their expression during bacterial and parasitic infection☆

(2010) Tiehui Wang et al.   FISH & SHELLFISH IMMUNOLOGY

T cell diversity and TcR repertoires in teleost fish

(2010) R. Castro et al.   FISH & SHELLFISH IMMUNOLOGY

Dissecting the roles of Raf- and PI3K-signalling pathways in melanoma formation and progression in a zebrafish model

(2009) C. Michailidou et al.   Disease Models & Mechanisms

Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio

(2009) Suman Mitra et al.   FEBS Journal

Oxazolone-Induced Enterocolitis in Zebrafish Depends on the Composition of the Intestinal Microbiota

(2009) Sylvia Brugman et al.   GASTROENTEROLOGY

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

(2009) Fernando Cruz-Guilloty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD4 and CD8: an inside-out coreceptor model for innate immune cells

(2009) Derrick Gibbings et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Transcription factor GATA-3 in Atlantic salmon (Salmo salar): Molecular characterization, promoter activity and expression analysis

(2009) Jaya Kumari et al.   MOLECULAR IMMUNOLOGY

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell

Comprehensive clarification of two paralogous interleukin 4/13 loci in teleost fish

(2008) Maki Ohtani et al.   IMMUNOGENETICS

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

(2008) Takeshi Egawa et al.   NATURE IMMUNOLOGY