Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis

Compstatin analog Cp40 inhibits complement dysregulation in vitro in C3 glomerulopathy

(2015) Yuzhou Zhang et al.   IMMUNOBIOLOGY

Interleukin 23 Levels Are Increased in Carotid Atherosclerosis

(2015) Azhar Abbas et al.   STROKE

Cholesterol Crystals Induce Complement-Dependent Inflammasome Activation and Cytokine Release

(2014) E. O. Samstad et al.   JOURNAL OF IMMUNOLOGY

Mitochondria and the Lectin Pathway of Complement

(2013) Christel R. Brinkmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

(2012) Dávid Héja et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mannose-Binding Lectin Deficiency Is Associated with Myocardial Infarction: The HUNT2 Study in Norway

(2012) Inga Thorsen Vengen et al.   PLoS One

Mannose-binding lectin serine proteases and associated proteins of the lectin pathway of complement: Two genes, five proteins and many functions?

(2011) Tang Yongqing et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Serum concentration and interaction properties of MBL/ficolin associated protein-1

(2010) Mikkel-Ole Skjoedt et al.   IMMUNOBIOLOGY

A Novel Mannose-binding Lectin/Ficolin-associated Protein Is Highly Expressed in Heart and Skeletal Muscle Tissues and Inhibits Complement Activation

(2010) Mikkel-Ole Skjoedt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate Immune Proteins C1q and Mannan-Binding Lectin Enhance Clearance of Atherogenic Lipoproteins by Human Monocytes and Macrophages

(2010) D. A. Fraser et al.   JOURNAL OF IMMUNOLOGY

Molecular Intercommunication between the Complement and Coagulation Systems

(2010) U. Amara et al.   JOURNAL OF IMMUNOLOGY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Functional Analysis of Ficolin-3 Mediated Complement Activation

(2010) Estrid Hein et al.   PLoS One

Macrophage-Specific Expression of Mannose-Binding Lectin Controls Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

(2009) Robert A. Matthijsen et al.   CIRCULATION

MBL-associated serine protease-3 circulates in high serum concentrations predominantly in complex with Ficolin-3 and regulates Ficolin-3 mediated complement activation

(2009) Mikkel-Ole Skjoedt et al.   IMMUNOBIOLOGY

Synergy between Ficolin-2 and Pentraxin 3 Boosts Innate Immune Recognition and Complement Deposition

(2009) Ying Jie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into the Recognition Properties of Human Ficolins

(2009) Virginie Garlatti et al.   Journal of Innate Immunity

The alternative complement pathway revisited

(2008) Morten Harboe et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Characterization of a polymorphism in the coding sequence of FCN3 resulting in a Ficolin-3 (Hakata antigen) deficiency state

(2008) Lea Munthe-Fog et al.   MOLECULAR IMMUNOLOGY

The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma

(2008) Christian Honoré et al.   MOLECULAR IMMUNOLOGY