Knockdown of growth differentiation factor-15 inhibited nonsmall cell lung cancer through inactivating PTEN/PI3K/AKT signaling pathway

LncRNA SNHG12 in extracellular vesicles derived from carcinoma-associated fibroblasts promotes cisplatin resistance in non-small cell lung cancer cells

(2022) Deli Tan et al.   Bioengineered

Long non-coding RNA DEPDC1-AS1 promotes proliferation and migration of human gastric cancer cells HGC-27 via the human antigen R–F11R pathway

(2022) Wei Xu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Growth differentiation factor-15 and lactoferrin immuno-expression in breast cancer: relationship with body iron-status and survival outcome

(2021) Zheng Zhang et al.   BIOMETALS

Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain: OSIREX-Spanish Lung Cancer Group

(2021) Mariano Provencio et al.   BMC CANCER

Growth differentiation factor-15 promotes immune escape of ovarian cancer via targeting CD44 in dendritic cells

(2021) Yunge Gao et al.   EXPERIMENTAL CELL RESEARCH

Growth and differentiation factor 15 and NF‐κB expression in benign prostatic biopsies and risk of subsequent prostate cancer detection

(2021) Benjamin A. Rybicki et al.   Cancer Medicine

Associations Between Plasma Growth and Differentiation Factor-15 with Aging Phenotypes in Muscle, Adipose Tissue, and Bone

(2021) Seung Hun Lee et al.   CALCIFIED TISSUE INTERNATIONAL

First-in-human phase 1 study of budigalimab, an anti-PD-1 inhibitor, in patients with non-small cell lung cancer and head and neck squamous cell carcinoma

(2021) Antoine Italiano et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Roles and Regulation of Growth differentiation factor-15 in the Immune and tumor microenvironment

(2021) Rathna Silviya Lodi et al.   HUMAN IMMUNOLOGY

Qizhen capsule inhibits colorectal cancer by inducing NAG-1/GDF15 expression that mediated via MAPK/ERK activation

(2021) Dandan Guo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Total flavonoids of Taraxacum mongolicum inhibit non-small cell lung cancer by regulating immune function

(2021) Le Kang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Modulating Properties of Piroxicam, Meloxicam and Oxicam Analogues against Macrophage-Associated Chemokines in Colorectal Cancer

(2021) Paulina Lewandowska et al.   MOLECULES

B7‐1 and programmed cell death‐ligand 1 in primary and lymph node metastasis lesions of non‐small cell lung carcinoma

(2021) Takehiro Yamada et al.   Cancer Medicine

Growth Differentiation Factor 15 Promotes Progression of Esophageal Squamous Cell Carcinoma via TGF-β Type II Receptor Activation

(2020) Maiko Okamoto et al.   PATHOBIOLOGY

Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity

(2020) Yasmin Husaini et al.   PLoS One

MiR-210 in exosomes derived from CAFs promotes non-small cell lung cancer migration and invasion through PTEN/PI3K/AKT pathway

(2020) Fang Yang et al.   CELLULAR SIGNALLING

Comparison of cancer control between segmentectomy and wedge resection in patients with clinical stage IA non-small cell lung cancer

(2020) Yasuhiro Tsutani et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

GDF15 knockdown suppresses cervical cancer cell migration in vitro through the TGF‐β/Smad2/3/Snail1 pathway

(2020) Li Li et al.   FEBS Open Bio

miR-144-3p Contributes to the Development of Thyroid Tumors Through the PTEN/PI3K/AKT Pathway

(2020) Hui-Ling Cao et al.   Cancer Management and Research

Hepatic stellate cells in hepatocellular carcinoma promote tumor growth via growth differentiation factor 15 production

(2020) Yuta Myojin et al.   GASTROENTEROLOGY

Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling

(2018) Honglei Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

CircVRK1 regulates tumor progression and radioresistance in esophageal squamous cell carcinoma by regulating miR-624-3p/PTEN/PI3K/AKT signaling pathway

(2018) Yunlong He et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

OCF can repress tumor metastasis by inhibiting epithelial–mesenchymal transition involved in PTEN/PI3K/AKT pathway in lung cancer cells

(2017) Ye Yang et al.   PLoS One

GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways

(2015) Naoki Urakawa et al.   LABORATORY INVESTIGATION

GDF15 is a potential predictive biomarker for TPF induction chemotherapy and promotes tumorigenesis and progression in oral squamous cell carcinoma

(2014) C. Z. Yang et al.   ANNALS OF ONCOLOGY

The multiple facets of the TGF-β family cytokine growth/differentiation factor-15/macrophage inhibitory cytokine-1

(2013) Klaus Unsicker et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells

(2012) D. J. Mulholland et al.   CANCER RESEARCH