Oxidative stress‐induced lncRNA CYLD‐AS1 promotes RPE inflammation via Nrf2/ miR ‐134‐5p/ NF‐κB signaling pathway

A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator

(2022) Jie Guo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Nrf2 signaling activation by a small molecule activator compound 16 inhibits hydrogen peroxide-induced oxidative injury and death in osteoblasts

(2022) Jing-wei Zhao et al.   Cell Death Discovery

LNCcation: lncRNA localization and function

(2021) Mary Catherine Bridges et al.   JOURNAL OF CELL BIOLOGY

VEGFR1 signaling in retinal angiogenesis and microinflammation

(2021) Akiyoshi Uemura et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Molecular Mechanisms Related to Oxidative Stress in Retinitis Pigmentosa

(2021) Carla Enrica Gallenga et al.   Antioxidants

Maintaining blood retinal barrier homeostasis to attenuate retinal ischemia-reperfusion injury by targeting the KEAP1/NRF2/ARE pathway with lycopene

(2021) Hao Huang et al.   CELLULAR SIGNALLING

Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors

(2021) Miguel Flores‐Bellver et al.   Journal of Extracellular Vesicles

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

(2020) Maria Grazia Vizioli et al.   GENES & DEVELOPMENT

Circular Noncoding RNA NR3C1 Acts as a miR-382-5p Sponge to Protect RPE Functions via Regulating PTEN/AKT/mTOR Signaling Pathway

(2020) Xue Chen et al.   MOLECULAR THERAPY

Exosomes derived from RPE cells under oxidative stress mediate inflammation and apoptosis of normal RPE cells through Apaf1/caspase-9 axis

(2020) Yifeng Ke et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

(2020) Kai Kaarniranta et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Long Noncoding RNAs: Molecular Modalities to Organismal Functions

(2020) John L. Rinn et al.   Annual Review of Biochemistry

Safflor Yellow B Attenuates Ischemic Brain Injury via Downregulation of Long Noncoding AK046177 and Inhibition of MicroRNA-134 Expression in Rats

(2020) Chaoyun Wang et al.   Oxidative Medicine and Cellular Longevity

Long noncoding RNA Hotair facilitates retinal endothelial cell dysfunction in diabetic retinopathy

(2020) Di Zhao et al.   CLINICAL SCIENCE

m 6 A methyltransferase METTL3 promotes retinoblastoma progression via PI3K/AKT/mTOR pathway

(2020) Han Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide-Treated RPE Cells through Activation of the Nrf2 Signaling Pathway

(2020) Yuanyuan Du et al.   Oxidative Medicine and Cellular Longevity

DNMT1-mediated lncRNA MEG3 methylation accelerates endothelial-mesenchymal transition in diabetic retinopathy through the PI3K/AKT/mTOR signaling pathway

(2020) Yue He et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Age-related macular degeneration: current knowledge of zinc metalloproteinases involvement

(2019) Francesca Liva et al.   CURRENT DRUG TARGETS

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Volatile Evolution of Long Non-Coding RNA Repertoire in Retinal Pigment Epithelium: Insights from Comparison of Bovine and Human RNA Expression Profiles

(2019) Olga A. Postnikova et al.   Genes

LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury

(2019) Peixing Wan et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors

(2019) Emily E. Brown et al.   Redox Biology

Oxidative stress-mediated TXNIP loss causes RPE dysfunction

(2019) Min Ji Cho et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Extracellular matrix and oxidative stress regulate human retinal pigment epithelium growth

(2019) Steven S. Eamegdool et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration

(2019) Ravirajsinh N. Jadeja et al.   Redox Biology

ID2 protects retinal pigment epithelium cells from oxidative damage through p -ERK1/2/ID2/NRF2

(2018) Yuting Fan et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Nuclear Long Noncoding RNAs: Key Regulators of Gene Expression

(2018) Qinyu Sun et al.   TRENDS IN GENETICS

Antioxidant response elements: Discovery, classes, regulation and potential applications

(2018) Azhwar Raghunath et al.   Redox Biology

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

(2018) Szabolcs Felszeghy et al.   Redox Biology

The inhibition of NOTCH2 reduces UVB-induced damage in retinal pigment epithelium cells

(2017) Lanying Liu et al.   Molecular Medicine Reports

The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD

(2017) Sayantan Datta et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

(2017) Nady Golestaneh et al.   Cell Death & Disease

PTEN Reduced UVB-Mediated Apoptosis in Retinal Pigment Epithelium Cells

(2017) Jia He et al.   Biomed Research International

How do lncRNAs regulate transcription?

(2017) Yicheng Long et al.   Science Advances

Transcriptional Regulation by Nrf2

(2017) Claudia Tonelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Consequences of oxidative stress in age-related macular degeneration

(2012) Stuart G. Jarrett et al.   MOLECULAR ASPECTS OF MEDICINE

Vascular endothelial growth factor in eye disease

(2008) J.S. Penn et al.   PROGRESS IN RETINAL AND EYE RESEARCH