Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties
出版年份 2022 全文链接
标题
Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties
作者
关键词
-
出版物
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 239, Issue -, Pages 114507
出版商
Elsevier BV
发表日期
2022-06-04
DOI
10.1016/j.ejmech.2022.114507
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mapping Chromone-3-Phenylcarboxamide Pharmacophore: Quid Est Veritas?
- (2021) Francesco Mesiti et al. JOURNAL OF MEDICINAL CHEMISTRY
- Iron Metabolism in Ferroptosis
- (2020) Xin Chen et al. Frontiers in Cell and Developmental Biology
- Development of a PEGylated-Based Platform for Efficient Delivery of Dietary Antioxidants Across the Blood–Brain Barrier
- (2018) Carlos Fernandes et al. BIOCONJUGATE CHEMISTRY
- Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis
- (2018) Joana Reis et al. JOURNAL OF MEDICINAL CHEMISTRY
- PEGylated PLGA Nanoparticles As a Smart Carrier to Increase the Cellular Uptake of a Coumarin-Based Monoamine Oxidase B Inhibitor
- (2018) Carlos Fernandes et al. ACS Applied Materials & Interfaces
- Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?
- (2017) André Fonseca et al. JOURNAL OF MEDICINAL CHEMISTRY
- Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances
- (2017) Joana Reis et al. JOURNAL OF MEDICINAL CHEMISTRY
- A new paradigm for navigating compound property related drug attrition
- (2016) Patrick Barton et al. DRUG DISCOVERY TODAY
- Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors
- (2016) Joana Reis et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry
- (2015) F. Cagide et al. CHEMICAL COMMUNICATIONS
- OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins
- (2015) Edward Harder et al. Journal of Chemical Theory and Computation
- Chromone: A Valid Scaffold in Medicinal Chemistry
- (2014) Alexandra Gaspar et al. CHEMICAL REVIEWS
- Towards the Discovery of a Novel Class of Monoamine Oxidase Inhibitors: Structure-Property-Activity and Docking Studies on Chromone Amides
- (2011) Alexandra Gaspar et al. ChemMedChem
- Chromone, a Privileged Scaffold for the Development of Monoamine Oxidase Inhibitors
- (2011) Alexandra Gaspar et al. JOURNAL OF MEDICINAL CHEMISTRY
- Evaluation of Drugs With Specific Organ Toxicities in Organ-Specific Cell Lines
- (2011) Zhiwu Lin et al. TOXICOLOGICAL SCIENCES
- Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B
- (2010) Stefano Alcaro et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors
- (2010) Alexandra Gaspar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment
- (2009) K Ray Chaudhuri et al. LANCET NEUROLOGY
- Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness
- (2006) Moussa B H Youdim et al. BRITISH JOURNAL OF PHARMACOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now