Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy

Heme-oxygenase-1 implications in cell morphology and the adhesive behavior of prostate cancer cells

(2015) Geraldine Gueron et al.   Oncotarget

SRC: A Century of Science Brought to the Clinic

(2015) Alexey Aleshin et al.   NEOPLASIA

Src, a potential target for overcoming trastuzumab resistance in HER2-positive breast carcinoma

(2014) G Peiró et al.   BRITISH JOURNAL OF CANCER

15-Deoxy-Δ12,14-prostaglandin J2induces p53 expression through Nrf2-mediated upregulation of heme oxygenase-1 in human breast cancer cells

(2014) D. H. Kim et al.   FREE RADICAL RESEARCH

Protective role of HO-1 and carbon monoxide in ethanol-induced hepatocyte cell death and liver injury in mice

(2014) Bakytzhan Bakhautdin et al.   JOURNAL OF HEPATOLOGY

The Cleaved Cytoplasmic Tail of Polycystin-1 Regulates Src-Dependent STAT3 Activation

(2014) J. J. Talbot et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Signal peptide peptidase-mediated nuclear localization of heme oxygenase-1 promotes cancer cell proliferation and invasion independent of its enzymatic activity

(2014) F-F Hsu et al.   ONCOGENE

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Regulation of Autophagy in Oxygen-Dependent Cellular Stress

(2013) Stefan W. Ryter et al.   CURRENT PHARMACEUTICAL DESIGN

Nuclear Translocation of Heme Oxygenase-1 Confers Resistance to Imatinib in Chronic Myeloid Leukemia Cells

(2013) Daniele Tibullo et al.   CURRENT PHARMACEUTICAL DESIGN

Heme oxygenase-1 aggravates heat stress-induced neuronal injury and decreases autophagy in cerebellar Purkinje cells of rats

(2013) Chuan-Wang Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Proteomic strategy for probing complementary lethality of kinase inhibitors against pancreatic cancer

(2013) Jin-Gyun Lee et al.   PROTEOMICS

Heme oxygenase-1 expression in human gliomas and its correlation with poor prognosis in patients with astrocytoma

(2013) Norberto A. Gandini et al.   TUMOR BIOLOGY

Role of STAT3 in Cancer Metastasis and Translational Advances

(2013) Mohammad Zahid Kamran et al.   Biomed Research International

Smad7 sensitizes A549 lung cancer cells to cisplatin-induced apoptosis through heme oxygenase-1 inhibition

(2012) Woo-Kwang Jeon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers

(2012) Xin-Sheng Deng et al.   CELL CYCLE

Heme Oxygenase-1 in Tumor Biology and Therapy

(2012) Halina Was et al.   CURRENT DRUG TARGETS

Heme Oxygenase-1 Promotes Survival of Renal Cancer Cells through Modulation of Apoptosis- and Autophagy-regulating Molecules

(2012) Pallavi Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Src: a potential target for the treatment of triple-negative breast cancer

(2011) D. Tryfonopoulos et al.   ANNALS OF ONCOLOGY

Autophagy as a mediator of chemotherapy-induced cell death in cancer

(2011) Annick Notte et al.   BIOCHEMICAL PHARMACOLOGY

Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice

(2011) Evie H. Carchman et al.   HEPATOLOGY

Interleukin-19 (IL-19) Induces Heme Oxygenase-1 (HO-1) Expression and Decreases Reactive Oxygen Species in Human Vascular Smooth Muscle Cells

(2011) Khatuna Gabunia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

(2011) Lauren L.C. Marotta et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer invasion and resistance: interconnected processes of disease progression and therapy failure

(2011) Stephanie Alexander et al.   TRENDS IN MOLECULAR MEDICINE

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract

(2010) Jia-Shiong Chen et al.   ATHEROSCLEROSIS

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

A novel role of IKKα in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression

(2010) Lun Song et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Haem oxygenase (HO): an overlooked enzyme of plant metabolism and defence

(2010) G. S. Shekhawat et al.   JOURNAL OF EXPERIMENTAL BOTANY

Heme Oxygenase-1 Inhibits Renal Tubular Macroautophagy in Acute Kidney Injury

(2010) S. Bolisetty et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy and Tumorigenesis

(2010) Srirupa Roy et al.   Seminars in Immunopathology

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

Autophagy genes as tumor suppressors

(2009) Chengyu Liang et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy in tumour suppression and promotion

(2009) Andreas Brech et al.   Molecular Oncology

Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

(2008) M. A. Qadir et al.   BREAST CANCER RESEARCH AND TREATMENT

Inducers of Heme Oxygenase-1

(2008) M. Ferrandiz et al.   CURRENT PHARMACEUTICAL DESIGN

Involvement of Protective Autophagy in TRAIL Resistance of Apoptosis-defective Tumor Cells

(2008) Jie Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sodium arsenite induces ROS generation, DNA oxidative damage, HO-1 and c-Myc proteins, NF-κB activation and cell proliferation in human breast cancer MCF-7 cells

(2008) Ruben Ruiz-Ramos et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62

(2008) J-P Pursiheimo et al.   ONCOGENE