Article
Biochemistry & Molecular Biology
Piyachat Chuysinuan, Patcharakamon Nooeaid, Thanyaluck Thanyacharoen, Supanna Techasakul, Prasit Pavasant, Kavita Kanjanamekanant
Summary: The study demonstrates the potential use of synthetic HA-incorporated fibroin-alginate hydrogel as a scaffold for bone regeneration in dentistry, showing good biocompatibility. The hydrogel exhibits high swelling ratio and degradation properties in vitro, but further in vivo studies are needed to validate its clinical application potential.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Yunfei Tan, Lei Ma, Xiangyu Chen, Yaqin Ran, Qiulan Tong, Liwen Tang, Xudong Li
Summary: The interfacial mismatch between rigid hydroxyapatite and soft polysaccharide phase in natural polysaccharide/hydroxyapatite hydrogels remains a challenge in bone tissue engineering. In this study, hyaluronic acid was used as a template for biological mineralization to synthesize hyaluronic acid/hydroxyapatite hybrid particles. These particles were then introduced into hydroxyapatite composite hydrogels, which showed increased storage modulus and excellent cytocompatibility. The self-healing hydrogels, suitable for cell encapsulation, hold promise for bone defect repair.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Composites
Elham Sadeghi, Seyed Mojtaba Zebarjad, Farzaneh Khademi, Elham Bagherzadeh
Summary: In this study, PCL/Ge/HA core-shell nanocomposites were produced using coaxial electrospinning method. The resulting nanofibrous scaffolds showed good mechanical properties and biological activity, making them promising candidates for bone scaffolds.
POLYMER COMPOSITES
(2022)
Article
Materials Science, Multidisciplinary
Myoung Hwan Kim, Elna Paul Chalisserry, Sudip Mondal, Junghwan Oh, Seung Yun Nam
Summary: This study combined HA and SiHA with gelatin to develop a bioactive membrane for GBR, showing advantages in biocompatibility and promoting osteogenic activity.
Article
Materials Science, Ceramics
Melike Nur Ozder, Fatih Ciftci, Ozge Rencuzogullari, Elif Damla Arisan, Cem Bulent Ustundag
Summary: This study investigates the properties of in situ synthesis of graphene oxide-hydroxyapatite (GO/HA) nanocomposite materials with different doping ratios for bone tissue support applications. The results show that scaffolds containing 0.5% and 1% GO (w/w) exhibit excellent cell proliferation and adhesion, making them promising materials for bone support applications.
CERAMICS INTERNATIONAL
(2023)
Article
Biotechnology & Applied Microbiology
Darlin Lantigua, Xinchen Wu, Sanika Suvarnapathaki, Michelle A. Nguyen, Gulden Camci-Unal
Summary: This study investigated the osteoinductive capacity of GelMA hydrogels containing bone meal powder particles, showing promising potential for enhancing bone formation. The scaffold displayed enhanced mechanical performance and promoted the differentiation of pre-osteoblast cells in vitro, while also demonstrating promising biocompatibility and biodegradation properties in vivo. The physical and biological properties of this biomaterial can be tuned based on the concentration of bone meal powder in GelMA scaffolds, offering a new composite scaffold for bone tissue engineering.
BIOENGINEERING-BASEL
(2021)
Article
Pharmacology & Pharmacy
Eduardo Anitua, Mar Zalduendo, Maria Troya, Itsasne Erezuma, Izeia Lukin, Raquel Hernaez-Moya, Gorka Orive
Summary: The study investigated the potential of three different bioinks based on gelatin and alginate for regenerative medicine. The bioinks containing hydroxyapatite and PRGF showed the highest cell compatibility and promoted osteogenic differentiation.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Materials Science, Multidisciplinary
Zhiming Zhang, Zijie Rong, Guofeng Wu, Yihan Wang, Zhiwen Tan, Juan Zheng, Yanglei Jin, Zhihao Liang, Chun Liu, Jiasong Guo, Lixin Zhu
Summary: The study introduced a controlled-oxygen-generating composite scaffold to enhance seed cell survival and improve bone defect reconstruction.
APPLIED MATERIALS TODAY
(2021)
Article
Engineering, Biomedical
Shravanya Gundu, Ajay Kumar Sahi, Neelima Varshney, Johny Varghese, Niraj K. Vishwakarma, Sanjeev Kumar Mahto
Summary: This study reports the fabrication and characterization of a novel luffa-based scaffold, which exhibits good porosity and mechanical strength comparable to native human bone, suggesting great potential for bone tissue engineering applications.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2022)
Article
Biochemistry & Molecular Biology
Anna Szabo, Rolando Pasquariello, Pedro F. Costa, Radmila Pavlovic, Indi Geurs, Koen Dewettinck, Chris Vervaet, Tiziana A. L. Brevini, Fulvio Gandolfi, Sandra Van Vlierberghe
Summary: In order to make fishmeal more accessible to the European population, a new 3D culture platform has been developed to replace the time-consuming and expensive feeding trials currently used to evaluate fish feed. This new platform can mimic the microenvironment of the intestinal mucosa in vitro, with suitable permeability for nutrients and medium-sized marker molecules, mechanical properties similar to the intestinal architecture, and can be processed with light-based 3D printing. The combination of scaffold and a novel rainbow trout intestinal epithelial cell line showed scaffold biocompatibility.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Ugo D'Amora, Alfredo Ronca, Stefania Scialla, Alessandra Soriente, Paola Manini, Jun Wei Phua, Christoph Ottenheim, Alessandro Pezzella, Giovanna Calabrese, Maria Grazia Raucci, Luigi Ambrosio
Summary: The study developed a photocrosslinkable biomaterial ink, methacrylated GG (GGMA), by chemically modifying gellan gum (GG) with methacrylic moieties. GGMA was then functionalized with bioactive compounds such as black soldier fly eumelanin (BSF-Eumel) or hydroxyapatite nanoparticles (HAp). Different ink formulations were used to 3D print scaffolds, and the ones with higher GGMA concentration and percentage of infill showed the best morphological and mechanical properties. The scaffolds demonstrated the capability to support cell growth and differentiation, with BSF-Eumel promoting cell proliferation and GGMA and HAp leading to higher alkaline phosphatase activity expression. Overall, these biomaterial inks have potential for 3D-printed bone tissue-engineered scaffolds.
Article
Engineering, Biomedical
Aylin Kara, Thomas Distler, Christian Polley, Dominik Schneidereit, Hermann Seitz, Oliver Friedrich, Funda Tihminlioglu, Aldo R. Boccaccini
Summary: This study demonstrates the feasibility of using decellularized bone particles as reinforcement agents in gelatin-based scaffolds for bone tissue engineering. The fabricated 3D scaffolds showed homogenous distribution of the reinforcement agents and exhibited enhanced mechanical properties and degradation rates. The scaffolds also demonstrated bioactivity and cytocompatibility, making them potential candidates for bone tissue engineering.
MATERIALS TODAY BIO
(2022)
Article
Materials Science, Multidisciplinary
Yihan Li, Zehao Yu, Fanrong Ai, Chunxuan Wu, Kui Zhou, Chuanliang Cao, Wenchao Li
Summary: The study demonstrates that the PCL scaffold with added HA and extra surface morphology shows improved mechanical strength, surface properties, and enhanced cell proliferation and osteogenic differentiation.
MATERIALS & DESIGN
(2021)
Article
Veterinary Sciences
Zihang Ma, Xiaoying Guo, Jun Zhang, Qifeng Jiang, Wuying Liang, Wenxin Meng, Shuaijiang Chen, Yufan Zhu, Cundong Ye, Kun Jia
Summary: This study aimed to evaluate the therapeutic effect of combining canine bone marrow mesenchymal stem cells (cBMSCs) with gelatin-nano-hydroxyapatite (Gel-nHAP) on bone defect diseases in dogs. The results showed that Gel-nHAP supported the attachment of cBMSCs and exhibited good biocompatibility. In animal experiments, significant cortical bone growth was observed in the Gel-nHAP group at week 8 and in the cBMSCs-Gel-nHAP group at week 4.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Tansza Setiana Putri, Devi Rianti, Priyawan Rachmadi, Anita Yuliati
Summary: A composite scaffold was successfully fabricated using beta-tricalcium phosphate (beta TCP) extracted from limestone, mixed with chitosan and gelatin. The study optimized the fabrication process and evaluated the effect of glutaraldehyde on scaffold characteristics. Results showed that lower porosity led to higher compressive strength in the cross-linked scaffolds.
Article
Engineering, Multidisciplinary
Keyu Zhu, Xitao Zheng, Jing Peng, Jiaming Sun, Ruilin Huang, Leilei Yan
Summary: This paper discusses the influence of multiple impacts on the compression strength of honeycomb sandwich structures with composite face sheets. It is found that the size of the impactor affects the turning point of the compression strength. Additionally, high impact energy leads to damage in the bottom face sheet and reduces the overall compression strength.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Danqian Wang, Yanfei Yue, Jueshi Qian
Summary: Magnesium Potassium Phosphate Cement (MKPC) as a binder for steel rebars shows improved corrosion resistance when subjected to carbonation, due to the increase in pH and the formation of a more protective oxide film.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Zhibin Li, Wenyu Wang, Pengcheng Xue, Xingyu Wei, Jian Xiong
Summary: This work proposes a design approach and manufacturing method for carbon fiber reinforced plastic (CFRP) corrugated sandwich truncated cones (CSTC) to improve their anti-debonding ability and ensure reliability. The study establishes theoretical models for CSTCs' stiffness and failure modes, which are verified through experiments and finite element analysis (FEA). The research reveals the effect of geometric parameters on failure modes and performs an optimal design for CSTC structures. The findings have significant implications for the design and application of lightweight CSTCs in constructions, such as launch vehicle adapters.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Mingyu Zhang, Lei Chu, Jiahua Chen, Fuxun Qi, Xiaoyan Li, Xinliang Chen, Deng-Guang Yu
Summary: This review summarizes the different structures and construction methods of fibrous membranes with asymmetric wettability. It also reviews the biological applications of these membranes and suggests future challenges.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
E. Mofakhami, L. Gervat, B. Fayolle, G. Miquelard-Garnier, C. Ovalle, L. Laiarinandrasana
Summary: This study investigates the effects of fibre concentration on the mechanical response of welded glass-fibre-reinforced polypropylene (GF-PP). Experimental observations reveal a significant reduction in weld ratio, up to 60%, indicating a decreased strength compared to the bulk material. Increasing fibre content in the welded material results in a decrease in stress at break and strain at the maximum stress. The use of DIC technique and X-ray microtomography further confirms the localized strain amplification in the welded zone due to the significant increase in fibre density.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Emad Pourahmadi, Farjad Shadmehri, Rajamohan Ganesan
Summary: This research compares the mechanical properties of laminates manufactured using automated fiber placement and conventional autoclave curing methods. The results show that laminates manufactured using automated fiber placement have a lower interlaminar shear strength compared to laminates reconsolidated using autoclave curing. A finite element simulation method is proposed to quantitatively analyze these differences.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Johnny Jakobsen, Benny Endelt, Fahimeh Shakibapour
Summary: This study proposes a new bolted/pinned joining method for composite applications, which improves load transfer by introducing a patch-type reinforcement. Experimental results demonstrate significant improvements in both static and fatigue load conditions compared to existing methods. Finite element simulations highlight the advantage of this method, as it creates a more efficient load-transferring mechanism through different stress distributions.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Gisele G. Cintra, Janine D. Vieira, Daniel C. T. Cardoso, Thomas Keller
Summary: This paper proposes a novel approach to assess multi-crack behavior in layered fiber-polymer composites. The generated Compliance and R-curves provide useful insights into understanding the multiple delamination process and allow for separate evaluation of strain energy release rate (SERR) for each crack. The developed cohesive zone model successfully simulates the failure process zone of three parallel cracks, showing good agreement between the numerical model and experimental results.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Renil Thomas Kidangan, Sreedhar Unnikrishnakurup, C. Krishnamurthy, Krishnan Balasubramaniam
Summary: The induction heating process can accurately identify fiber orientation and stacking order, making it a valuable tool for large-area inspection and quality control in manufacturing fiber-reinforced composites.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Sungjun Hwang, Yousoo Han, Douglas J. Gardner
Summary: Bleached Kraft pulp, unbleached Kraft pulp, and old corrugated cardboard pulp are suitable for producing cellulose nanofibril suspensions. Spray drying is a fast, simple, cost-effective, and scalable drying method. Spray-dried cellulose nanofibrils can be used as reinforcing materials in polypropylene matrices. The particle size of cellulose nanofibrils affects the material properties.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Mehdi Mahdavi, Abbas Zolfaghari
Summary: This study aims to improve the recovery forces of shape memory polymers (SMPs) through material extrusion additive manufacturing. By using glass fiber (GF) as reinforcement and manufacturing multi-layer composite specimens, it was found that PLA with 6.62% GF exhibited the best recovery force, which was further optimized through annealing heat treatment.
COMPOSITES PART B-ENGINEERING
(2024)
Review
Engineering, Multidisciplinary
Xiang Ao, Antonio Vazquez-Lopez, Davide Mocerino, Carlos Gonzalez, De-Yi Wang
Summary: The vulnerability of natural fibers to heat and fire poses a significant challenge for their substitution of traditional fiber reinforcements in composite materials. Natural fiber/polymer composites (NFCs) are regarded as potential candidates for engineering applications due to their environmental friendliness and low-impact sourcing. Thus, appropriate approaches need to be implemented to enhance the fire safety of NFCs. This review summarizes and discusses the latest understanding of flammability and thermal properties of natural fibers, with a special focus on their interaction with polymer matrix in fire behavior. Additionally, the latest developments in flame-retardant approaches for NFCs are reviewed, covering both flame retardancy and fire structural integrity. Finally, future prospects and perspectives on fire safety of NFCs are proposed, providing insights into further advancements of NFCs.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Cheng Wang, Siqi Huo, Guofeng Ye, Bingtao Wang, Zhenghong Guo, Qi Zhang, Pingan Song, Hao Wang, Zhitian Liu
Summary: The demand for multifunctional, transparent epoxy resin with superior dielectric, mechanical, and fire-safety performances is increasing in modern industries. Researchers have developed an epoxidized, phosphaphenanthrene-containing poly(styrene butadiene styrene) (ESD) for advanced fire-safe epoxy resin, which maintains high transparency and improves UV-blocking property. The addition of 10 wt% ESD results in improved mechanical properties, decreased dielectric constant and loss, and outperformance compared to other fire-safe epoxy resins. This research provides an effective method for developing multifunctional flame-retardant epoxy resin.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Bo Pang, Heping Zheng, Zuquan Jin, Dongshuai Hou, Yunsheng Zhang, Xiaoyun Song, Yanan Sun, Zhiyong Liu, Wei She, Lin Yang, Mengyuan Li
Summary: This study develops an internal superhydrophobic material (ISM) using waste denitrification fly ash, which maintains stable hydrophobicity under harsh conditions of use and does not rely on expensive fluor-based surface modifications. The synthesized ISM has excellent matrix strength, strong waterproof properties, and retains superhydrophobicity even at damaged or friction interfaces.
COMPOSITES PART B-ENGINEERING
(2024)
Article
Engineering, Multidisciplinary
Meirbek Mussatayev, Qiuji Yi, Mark Fitzgerald, Vincent K. Maes, Paul Wilcox, Robert Hughes
Summary: Real-time monitoring of carbon fibre composites during Automated Fibre Placement (AFP) manufacturing remains a challenge for non-destructive evaluation (NDE) techniques. This study designed a directional eddy-current (EC) probe to evaluate the detectability of out-of-plane wrinkles. Experimental evaluations and finite element modeling were conducted to better understand the relationship between eddy-current density and defect detection. The findings suggest that the probe configuration with an asymmetric driver coil and differential pickup coils shows the best capability for wrinkle detection.
COMPOSITES PART B-ENGINEERING
(2024)