Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood

Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue

(2022) Marco Rosina et al.   Cell Metabolism

Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming

(2021) Jennyfer Levoux et al.   Cell Metabolism

Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes

(2021) Clair Crewe et al.   Cell Metabolism

Mitochondrial aspartate regulates TNF biogenesis and autoimmune tissue inflammation

(2021) Bowen Wu et al.   NATURE IMMUNOLOGY

Mitochondrial augmentation of CD34+ cells from healthy donors and patients with mitochondrial DNA disorders confers functional benefit

(2021) Elad Jacoby et al.   npj Regenerative Medicine

Blood contains circulating cell‐free respiratory competent mitochondria

(2020) Zahra Al Amir Dache et al.   FASEB JOURNAL

Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons

(2020) Chantell S Evans et al.   eLife

Bioenergetics Consequences of Mitochondrial Transplantation in Cardiomyocytes

(2020) Paria Ali Pour et al.   Journal of the American Heart Association

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

(2020) José A. Nicolás-Ávila et al.   CELL

Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity

(2020) Jonathan R. Brestoff et al.   Cell Metabolism

Autologous mitochondrial transplantation for cardiogenic shock in pediatric patients following ischemia-reperfusion injury

(2020) Alvise Guariento et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

High Fat Rodent Models of Type 2 Diabetes: From Rodent to Human

(2020) Nicole L. Stott et al.   Nutrients

Mitochondrial transplantation regulates antitumour activity, chemoresistance and mitochondrial dynamics in breast cancer

(2019) Jui-Chih Chang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection

(2019) Jayna J. Mistry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimizing Batch Effects in Mass Cytometry Data

(2019) Ronald P. Schuyler et al.   Frontiers in Immunology

Difference in Binding of Long- and Medium-Chain Fatty Acids with Serum Albumin: The Role of Macromolecular Crowding Effect

(2018) Tian-Tian Zhu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

(2018) Laleh Haghverdi et al.   NATURE BIOTECHNOLOGY

Delivery of exogenous mitochondria via centrifugation enhances cellular metabolic function

(2018) Mi Jin Kim et al.   Scientific Reports

Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry

(2018) Stéphane Chevrier et al.   Cell Systems

Mitochondrial damage associated molecular patterns released by lung transplants are associated with primary graft dysfunction

(2018) Davide Scozzi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Inflammatory mechanisms linking obesity and metabolic disease

(2017) Alan R. Saltiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Autologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury

(2017) Sitaram M. Emani et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

Tunneling nanotubes promote intercellular mitochondria transfer followed by increased invasiveness in bladder cancer cells

(2017) Jinjin Lu et al.   Oncotarget

Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy

(2017) Mu-En Wang et al.   Scientific Reports

Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity

(2017) Brittney R. Coats et al.   Cell Reports

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

(2017) Lan-Feng Dong et al.   eLife

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Discovery of a proteinaceous cellular receptor for a norovirus

(2016) R. C. Orchard et al.   SCIENCE

Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS

(2016) Megan V. Jackson et al.   STEM CELLS

Immune Regulation of Metabolic Homeostasis in Health and Disease

(2015) Jonathan R. Brestoff et al.   CELL

Structure-Function of CD36 and Importance of Fatty Acid Signal Transduction in Fat Metabolism

(2014) Marta Yanina Pepino et al.   Annual Review of Nutrition

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

(2014) L. H. Boudreau et al.   BLOOD

IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1α

(2014) Xingxing Kong et al.   CELL

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Vascular rarefaction mediates whitening of brown fat in obesity

(2014) Ippei Shimizu et al.   JOURNAL OF CLINICAL INVESTIGATION

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury

(2013) Akihiro Masuzawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mouse lines with photo-activatable mitochondria to study mitochondrial dynamics

(2012) Anh H. Pham et al.   GENESIS

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

CD36 as a lipid sensor

(2011) Céline Martin et al.   PHYSIOLOGY & BEHAVIOR

Mitochondrial Capture by a Transmissible Cancer

(2011) C. A. Rebbeck et al.   SCIENCE

Defining macrophage phenotype and function in adipose tissue

(2011) Elise Dalmas et al.   TRENDS IN IMMUNOLOGY

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

flowCore: a Bioconductor package for high throughput flow cytometry

(2009) Florian Hahne et al.   BMC BIOINFORMATICS

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

(2009) Yuan Xue et al.   Cell Metabolism

Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis

(2009) Naim Alkhouri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Injection of isolated mitochondria during early reperfusion for cardioprotection

(2008) James D. McCully et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy

(2008) Shane E. Kruse et al.   Cell Metabolism

Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

(2008) C. N. Lumeng et al.   DIABETES