Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones

(2022) Jack A. Collora et al.   IMMUNITY

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Immune checkpoint modulation enhances HIV-1 antibody induction

(2020) Todd Bradley et al.   Nature Communications

Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization

(2020) Qifeng Han et al.   Cell Reports

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

(2020) Samuel W. Kazer et al.   NATURE MEDICINE

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Immune Activation, Inflammation, and Non-AIDS Co-Morbidities in HIV-Infected Patients under Long-Term ART

(2019) Sonia Zicari et al.   Viruses-Basel

Long noncoding RNA MALAT1 releases epigenetic silencing of HIV-1 replication by displacing the polycomb repressive complex 2 from binding to the LTR promoter

(2019) Di Qu et al.   NUCLEIC ACIDS RESEARCH

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Dual-Specificity Phosphatases in Immunity and Infection: An Update

(2019) Roland Lang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation

(2019) Melissa-Rose Abrahams et al.   Science Translational Medicine

Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity

(2018) Eloy Cuadrado et al.   IMMUNITY

Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation

(2018) Lillian B. Cohn et al.   NATURE MEDICINE

HIV-1 replication in CD4 + T cells exploits the down-regulation of antiviral NEAT1 long non-coding RNAs following T cell activation

(2018) Hongbing Liu et al.   VIROLOGY

Single-Cell RNA-Seq Reveals Transcriptional Heterogeneity in Latent and Reactivated HIV-Infected Cells

(2018) Monica Golumbeanu et al.   Cell Reports

RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses

(2018) Todd Bradley et al.   CELL

Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency

(2018) Todd Bradley et al.   Cell Reports

Assessing inflammation and its role in comorbidities among persons living with HIV

(2018) Tess E. Peterson et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Mechanism of Interferon-Stimulated Gene Induction in HIV-1-Infected Macrophages

(2017) Najla Nasr et al.   JOURNAL OF VIROLOGY

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Single-cell analysis identifies cellular markers of the HIV permissive cell

(2017) Sylvie Rato et al.   PLoS Pathogens

Control of HIV-1 gene expression by SR proteins

(2016) Charlotte Mahiet et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dissecting How CD4 T Cells Are Lost During HIV Infection

(2016) Gilad Doitsh et al.   Cell Host & Microbe

Identification of Interferon-Stimulated Genes with Antiretroviral Activity

(2016) Melissa Kane et al.   Cell Host & Microbe

Antiretroviral Therapy for the Prevention of HIV-1 Transmission

(2016) Myron S. Cohen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Establishment and stability of the latent HIV-1 DNA reservoir

(2016) Johanna Brodin et al.   eLife

NK Cells in HIV Disease

(2016) Eileen Scully et al.   Current HIV/AIDS Reports

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Blimp-1, an Intrinsic Factor that Represses HIV-1 Proviral Transcription in Memory CD4+T Cells

(2015) Katarzyna Kaczmarek Michaels et al.   JOURNAL OF IMMUNOLOGY

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Human Hsp40 proteins, DNAJA1 and DNAJA2, as potential targets of the immune response triggered by bacterial DnaJ in rheumatoid arthritis

(2013) Agnieszka Kotlarz et al.   CELL STRESS & CHAPERONES

Systemic Effects of Inflammation on Health during Chronic HIV Infection

(2013) Steven G. Deeks et al.   IMMUNITY

NEAT1 Long Noncoding RNA and Paraspeckle Bodies Modulate HIV-1 Posttranscriptional Expression

(2013) Q. Zhang et al.   mBio

Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population

(2012) Alison J. Rodger et al.   AIDS

Innate Immune Sensing of HIV-1 by Dendritic Cells

(2012) Jeremy Luban   Cell Host & Microbe

INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

(2012) Irina Rusinova et al.   NUCLEIC ACIDS RESEARCH

Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection

(2011) Cynthia L Gay et al.   AIDS

Galectin-1 research in T cell immunity: Past, present and future

(2011) Filiberto Cedeno-Laurent et al.   CLINICAL IMMUNOLOGY

Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived Macrophages

(2011) C. Ochsenbauer et al.   JOURNAL OF VIROLOGY

Innate immune recognition and activation during HIV infection

(2010) Trine H Mogensen et al.   Retrovirology

Interleukin‐7 Receptor Signaling Is Deficient in CD4+T Cells from HIV‐Infected Persons and Is Inversely Associated with Aging

(2009) Douglas A. Bazdar et al.   JOURNAL OF INFECTIOUS DISEASES