The health risk assessment of heavy metals to human health through the consumption of Tilapia spp and catfish caught from Lake Mariut, Egypt

This work assesses the concentration of As, Cd, Pb, Hg, and Al in three of Tilapia species and catfish caught from Lake Mariut. As well as the human health risk and muscle biochemical composition. Besides, the antioxidant responses of different species. The average metal concentration order was Pb > As > Cd > Al > Hg. The Cd and Pb levels in all species; besides, the Hg levels in Oreochromis niloticus and Oreochromis aureus exceeded the maximum limits set by FAO, European legislation, and FAO/WHO. The human health risk was assessed using estimated dietary intakes, the target hazard quotient (THQ), and the carcinogenic risk (CR). THQAs was > 1 in all examined fishes and closer to 1 in THQCd, Hg. As well, CR level for As was higher than the permissible value. Tilapia zillii showed significant decreases in carbohydrates compared to Clarias gariepinus; also, ash content compared to C. gariepinus, O. niloticus, and O. aureus. Furthermore, water content compared to O. aureus. In contrast, significant increases of SOD in O. niloticus compared to C. gariepinus. In addition, CAT and GPx in O. aureus compared to C. gariepinus. Also, GR in both O. niloticus and O. aureus compared to C. gariepinus, and GSH in all of Tilapia spp. compared to C. gariepinus. Data obtained provide evidence of health risks to the consumers. Therefore, more caution is required.

Automated summary

This study assessed the concentration of As, Cd, Pb, Hg, and Al in Tilapia species and catfish from Lake Mariut, as well as their potential health risks and muscle composition. The results showed that Cd and Pb levels in all species, as well as Hg levels in Oreochromis niloticus and Oreochromis aureus, exceeded the maximum limits set by international regulations. The human health risk was evaluated using dietary intakes and hazard quotient calculations, indicating potential risks associated with the consumption of these fish. The study also observed variations in muscle composition and antioxidant responses among different species. These findings highlight the importance of ensuring food safety and consumer awareness.