Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages
出版年份 2016 全文链接
标题
Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages
作者
关键词
Pancreatic cancer, Cancerogenesis, Chemotherapy, Gemcitabine, Aspirin, Atorvastatin, Myeloid derived suppressor cells, Tumor associated macrophages
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 35, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-02-16
DOI
10.1186/s13046-016-0304-4
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Can daily intake of aspirin and/or statins influence the behavior of non-muscle invasive bladder cancer? A retrospective study on a cohort of patients undergoing transurethral bladder resection
- (2015) Antonio Luigi Pastore et al. BMC CANCER
- Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy
- (2015) Giuseppe Di Caro et al. GUT
- Atorvastatin promotes human monocyte differentiation toward alternative M2 macrophages through p38 mitogen-activated protein kinase-dependent peroxisome proliferator-activated receptor γ activation
- (2015) Ou Zhang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Aspirin and NSAID Chemoprevention, Gene-Environment Interactions, and Risk of Colorectal Cancer
- (2015) Richard C. Wender JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Gemcitabine sensitizes pancreatic cancer cells to the CTLs antitumor response induced by BCG-stimulated dendritic cells via a Fas-dependent pathway
- (2015) Qingshan Pei et al. PANCREATOLOGY
- Characterization of myeloid leukocytes and soluble mediators in pancreatic cancer: importance of myeloid-derived suppressor cells
- (2015) Svetlana Karakhanova et al. OncoImmunology
- Cancer treatment and survivorship statistics, 2014
- (2014) Carol E. DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma
- (2014) Ya-Chin Hou et al. CANCER
- B Cells Regulate Macrophage Phenotype and Response to Chemotherapy in Squamous Carcinomas
- (2014) Nesrine I. Affara et al. CANCER CELL
- Prognostic factors related to add-on dendritic cell vaccines on patients with inoperable pancreatic cancer receiving chemotherapy: a multicenter analysis
- (2014) Masanori Kobayashi et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Patients with pancreatic adenocarcinoma exhibit elevated levels of myeloid-derived suppressor cells upon progression of disease
- (2014) Joseph Markowitz et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer
- (2014) Roheena Z. Panni et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
- (2014) Yonit Lavin et al. CELL
- Complementary Induction of Immunogenic Cell Death by Oncolytic Parvovirus H-1PV and Gemcitabine in Pancreatic Cancer
- (2014) A. L. Angelova et al. JOURNAL OF VIROLOGY
- Metastasis risk after anti-macrophage therapy
- (2014) Ioanna Keklikoglou et al. NATURE
- Albumin-Bound Paclitaxel plus Gemcitabine in Pancreatic Cancer
- (2014) NEW ENGLAND JOURNAL OF MEDICINE
- Increased Levels of Granulocytic Myeloid-Derived Suppressor Cells in Peripheral Blood and Tumour Tissue of Pancreatic Cancer Patients
- (2014) Yazan S. Khaled et al. Journal of Immunology Research
- Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
- (2013) Y Ino et al. BRITISH JOURNAL OF CANCER
- Macrophage Regulation of Tumor Responses to Anticancer Therapies
- (2013) Michele De Palma et al. CANCER CELL
- Low-dose aspirin delays an inflammatory tumor progression in vivo in a transgenic mouse model of neuroblastoma
- (2013) Lena-Maria Carlson et al. CARCINOGENESIS
- The Differential Effects of Statins on the Risk of Developing Pancreatic Cancer: A Case–Control Study in Two Centres in the United Kingdom
- (2013) F. J. Carey et al. DIGESTIVE DISEASES AND SCIENCES
- Myeloid-Derived Suppressor Cells Enhance Stemness of Cancer Cells by Inducing MicroRNA101 and Suppressing the Corepressor CtBP2
- (2013) Tracy X. Cui et al. IMMUNITY
- IgG4 subclass antibodies impair antitumor immunity in melanoma
- (2013) Panagiotis Karagiannis et al. JOURNAL OF CLINICAL INVESTIGATION
- M2-polarized tumor-associated macrophages promoted epithelial–mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway
- (2013) Chao-Ying Liu et al. LABORATORY INVESTIGATION
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- Oligonucleotide Microarray Identifies Genes Differentially Expressed during Tumorigenesis of DMBA-Induced Pancreatic Cancer in Rats
- (2013) Jun-Chao Guo et al. PLoS One
- Atorvastatin and Simvastatin, but not Pravastatin, Up-regulate LPS-Induced MMP-9 Expression in Macrophages by Regulating Phosphorylation of ERK and CREB
- (2012) Dong Kun Lee et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The role of stroma in pancreatic cancer: diagnostic and therapeutic implications
- (2012) Mert Erkan et al. Nature Reviews Gastroenterology & Hepatology
- Statin Use and Reduced Cancer-Related Mortality
- (2012) Sune F. Nielsen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analysis of Pancreatic Cancer Microenvironment: Role of Macrophage Infiltrates and Growth Factors Expression
- (2012) Katarzyna Gardian et al. Journal of Cancer
- Exposure to statins and risk of common cancers: a series of nested case-control studies
- (2011) Yana Vinogradova et al. BMC CANCER
- miR-223 suppresses differentiation of tumor-induced CD11b+Gr1+myeloid-derived suppressor cells from bone marrow cells
- (2011) Qiaofei Liu et al. INTERNATIONAL JOURNAL OF CANCER
- Atorvastatin suppresses inflammatory response induced by oxLDL through inhibition of ERK phosphorylation, IκBα degradation, and COX-2 expression in murine macrophages
- (2011) Qin Shao et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- CD40 agonists—a promising new treatment for pancreatic cancer?
- (2011) Shreeya Nanda Nature Reviews Gastroenterology & Hepatology
- The statin-low cholesterol-cancer conundrum
- (2011) U. Ravnskov et al. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
- Statins and pancreatic cancer risk: a nested case–control study
- (2010) Marie C. Bradley et al. CANCER CAUSES & CONTROL
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Increase in frequency of myeloid-derived suppressor cells in mice with spontaneous pancreatic carcinoma
- (2009) Fei Zhao et al. IMMUNOLOGY
- Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice
- (2009) Hanh K. Le et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer
- (2009) Hiroshi Kurahara et al. JOURNAL OF SURGICAL RESEARCH
- Statins Are Not Associated With a Reduced Risk of Pancreatic Cancer at the Population Level, When Taken at Low Doses for Managing Hypercholesterolemia: Evidence From a Meta-Analysis of 12 Studies
- (2008) Stefanos Bonovas et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation
- (2008) Kamala P. Sundararaj et al. JOURNAL OF LEUKOCYTE BIOLOGY
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