Picomolar-sensitive β-amyloid fibril fluorophores by tailoring the hydrophobicity of biannulated π-elongated dioxaborine-dyes

CRANAD-28: A Robust Fluorescent Compound for Visualization of Amyloid Beta Plaques

(2020) Kathleen Ran et al.   MOLECULES

Visualization of soluble tau oligomers in TauP301L-BiFC transgenic mice demonstrates the progression of tauopathy

(2020) Seulgi Shin et al.   PROGRESS IN NEUROBIOLOGY

Hydrophobic Interaction: A Promising Driving Force for the Biomedical Applications of Nucleic Acids

(2020) Fan Xiao et al.   Advanced Science

Fluorescent Diagnostic Probes in Neurodegenerative Diseases

(2020) Jin Zhou et al.   ADVANCED MATERIALS

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

(2019) Francesco Panza et al.   Nature Reviews Neurology

Frontiers in Probing Alzheimer’s Disease Biomarkers with Fluorescent Small Molecules

(2019) Yong Woong Jun et al.   ACS Central Science

Harnessing Intramolecular Rotation to Enhance Two-photon Imaging of Aβ Plaques Through Minimizing Background Fluorescence

(2019) Jinwoo Shin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue

(2019) Marius Kollmer et al.   Nature Communications

Novel D–A–D based near-infrared probes for the detection of β-amyloid and Tau fibrils in Alzheimer's disease

(2018) Yuying Li et al.   CHEMICAL COMMUNICATIONS

Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores

(2018) Peter Verwilst et al.   CHEMICAL SOCIETY REVIEWS

New Perspectives of Alzheimer Disease Diagnosis – the Most Popular and Future Methods

(2018) Katarzyna Pietrzak et al.   Medicinal Chemistry

Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

(2018) Silvia A. Purro et al.   NATURE

A near-infrared fluorescent probe for amyloid-β aggregates

(2018) Misun Lee et al.   DYES AND PIGMENTS

Rational Design of in Vivo Tau Tangle-Selective Near-Infrared Fluorophores: Expanding the BODIPY Universe

(2017) Peter Verwilst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species

(2017) Yuyan Li et al.   Chemical Science

Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation

(2017) Christine Xue et al.   Royal Society Open Science

Discovery of boronic acid-based fluorescent probes targeting amyloid-beta plaques in Alzheimer’s disease

(2016) Seung-Jin Jung et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity

(2016) Sha Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques

(2015) Kaixiang Zhou et al.   CHEMICAL COMMUNICATIONS

Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid-β Plaques in Alzheimer’s Disease

(2015) Hualong Fu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Two-Photon Absorbing Dyes with Minimal Autofluorescence in Tissue Imaging: Application to in Vivo Imaging of Amyloid-β Plaques with a Negligible Background Signal

(2015) Dokyoung Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

(2015) Xueli Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

Efficient synthesis of fluorescent-PET probes based on [18F]BODIPY dye

(2014) Shuanglong Liu et al.   CHEMICAL COMMUNICATIONS

Evaluation of molecules based on the electron donor–acceptor architecture as near-infrared β-amyloidal-targeting probes

(2014) Hualong Fu et al.   CHEMICAL COMMUNICATIONS

Proteins Feel More Than They See: Fine-Tuning of Binding Affinity by Properties of the Non-Interacting Surface

(2014) Panagiotis L. Kastritis et al.   JOURNAL OF MOLECULAR BIOLOGY

Smart Near-Infrared Fluorescence Probes with Donor–Acceptor Structure for in Vivo Detection of β-Amyloid Deposits

(2014) Mengchao Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Noninvasive fluorescence imaging of small animals

(2013) A. ZELMER et al.   JOURNAL OF MICROSCOPY

Design and Synthesis of Curcumin Analogues for in Vivo Fluorescence Imaging and Inhibiting Copper-Induced Cross-Linking of Amyloid Beta Species in Alzheimer’s Disease

(2013) Xueli Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

BODIPY-Based Molecular Probe for Imaging of Cerebral β-Amyloid Plaques

(2012) Masahiro Ono et al.   ACS Chemical Neuroscience

Fluorescent 2-styrylpyridazin-3(2H)-one derivatives as probes targeting amyloid-beta plaques in Alzheimer’s disease

(2012) Yong Dae Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A two-photon fluorescent probe for amyloid-β plaques in living mice

(2012) Cheol Ho Heo et al.   CHEMICAL COMMUNICATIONS

A Qualitative Index of Spatial Extent in Charge-Transfer Excitations

(2011) Tangui Le Bahers et al.   Journal of Chemical Theory and Computation

Multiwfn: A multifunctional wavefunction analyzer

(2011) Tian Lu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Standards for photoluminescence quantum yield measurements in solution (IUPAC Technical Report)

(2011) Albert M. Brouwer   PURE AND APPLIED CHEMISTRY

A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu

(2010) Stefan Grimme et al.   JOURNAL OF CHEMICAL PHYSICS

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Toward a Generalized Treatment of the Solvent Effect Based on Four Empirical Scales: Dipolarity (SdP, a New Scale), Polarizability (SP), Acidity (SA), and Basicity (SB) of the Medium

(2009) Javier Catalán   JOURNAL OF PHYSICAL CHEMISTRY B

Design, Synthesis, and Testing of Difluoroboron-Derivatized Curcumins as Near-Infrared Probes for in Vivo Detection of Amyloid-β Deposits

(2009) Chongzhao Ran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development and Validation of the B3LYP/N07D Computational Model for Structural Parameter and Magnetic Tensors of Large Free Radicals

(2008) Vincenzo Barone et al.   Journal of Chemical Theory and Computation

Long-range corrected hybrid density functionals with damped atom–atom dispersion corrections

(2008) Jeng-Da Chai et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS