Article
Plant Sciences
Birute Karpaviciene
Summary: Changes in people's dependence on natural resources and information transmission may lead to the loss of traditional plant knowledge. This study collected knowledge about plant treatments in southwestern Lithuania, and found a decline in plant diversity used for healing in the past 20 years.
Article
Pharmacology & Pharmacy
Dhruba Khakurel, Yadav Uprety, Gyeongik Ahn, Joon-Yung Cha, Woe-Yeon Kim, Sung-Ho Lee, Sangeeta Rajbhandary
Summary: This study aims to document and analyze the diversity, distribution, and sustainability of traditional medicinal plants used by the Gurung people in western Nepal. The results show that the Gurung people possess rich traditional knowledge of medicinal plants, with herbs being the most dominant life form and stomach disorders being the most commonly treated illness.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Plant Sciences
Yunn Mi Mi Kyaw, Yingfeng Bi, Thaung Naing Oo, Xuefei Yang
Summary: The study documented 158 medicinal plant species used by the Mon people, with 78 therapeutic uses classified into 16 disease categories. Fabaceae was the most represented plant family, and leaf was the most commonly used plant part. Decoction and oral administration were the top preparation and administration methods.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Review
Plant Sciences
Stefania Monari, Maura Ferri, Mirko Salinitro, Annalisa Tassoni
Summary: This study analyzed published papers on the traditional medicinal use of wild and cultivated plants in Italy, identifying 1117 different species and categorizing them based on therapeutic applications. The results showed that the most commonly cited species were used for treating digestive and skin-ears-eyes-hair diseases, followed by genito-urinary and respiratory diseases. Thirteen important species were identified as potential sources for plant-based therapeutic remedies.
Article
Plant Sciences
Giulia Mattalia, Felina Graetz, Matthes Harms, Anna Segor, Alessio Tomarelli, Victoria Kieser, Stefan Zerbe, Andrea Pieroni
Summary: Mountain regions, such as Trentino-South Tyrol in the Eastern Alps, are fragile ecosystems with rich biodiversity that are under threat from global changes. This study examined the ethnomedicinal knowledge of the area through interviews with local inhabitants and compared the findings with studies conducted 25 years ago. The comparison revealed that many of the plants currently in use were also used in the past, suggesting a continuity in medicinal plant usage.
Article
Biodiversity Conservation
Cecilia Arjona-Garcia, Jose Blancas, Leonardo Beltran-Rodriguez, Citlalli Lopez Binnquist, Hortensia Colin Bahena, Ana Isabel Moreno-Calles, Jose Antonio Sierra-Huelsz, Xavier Lopez-Medellin
Summary: Urbanization in rural Mexico has led to a decline in knowledge and use of local wild species, impacting the conservation of biocultural heritage. Communities with higher levels of urbanization have greater knowledge of and use of introduced plant species, while communities with lower levels of urbanization have more knowledge of and use of wild plants. Urbanization can result in the disinterest and disuse of local medicinal flora, which could have implications for the ecosystems.
JOURNAL OF ETHNOBIOLOGY AND ETHNOMEDICINE
(2021)
Article
Pharmacology & Pharmacy
Gizem Emre, Ahmet Dogan, Mehmet Zeki Haznedaroglu, Ismail Senkardes, Mahmut Ulger, Aysen Satiroglu, Berivan Can Emmez, Osman Tugay
Summary: This study conducted in Mersin province, Turkey, compiled information on 93 plant taxa used for therapeutic purposes by local people. The most important medicinal plants identified were Hypericum perforatum, Cedrus libani, Quercus coccifera, Arum dioscoridis, and Juniperus drupaceae. The study found that traditional folk medicine usage is still common in rural areas of Mersin.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Khadidja Belhouala, Bachir Benarba
Summary: Traditional medicine plays a vital role in promoting scientific research on new therapeutic approaches. The study investigated the traditional knowledge and use of medicinal plants in treating various ailments by interviewing 40 traditional healers in Algeria. Findings revealed that leaves were the most commonly used plant parts, with decoction, raw usage, and infusion being the predominant modes of preparation. Furthermore, the research identified 15% of newly reported medicinal plant species and discovered 47 new therapeutic uses for 20 known plant species.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Plant Sciences
Ying Lin, Shao-ping Wang, Jia-yu Zhang, Zhao-yuan Zhuo, Xin-rou Li, Chuan-jia Zhai, Xiao-xue Li, Feng-hua Qi, Xia Ding, Cai-yun Chen, Jie Zhou, Jia Li, Qian Liu, Li-li Qiu, Yong-qing Zhang
Summary: The study aimed to investigate and record the medicinal plant taxa and their associated traditional knowledge in Gaomi City, China. A total of 181 species belonging to 137 genera and 65 families were collected in Gaomi City, with 7 of them not previously reported in China. The main preparation method for medicinal plants was decocting, and the most frequent mode of administration was oral.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Biodiversity Conservation
Mathewos Agize, Zemede Asfaw, Sileshi Nemomissa, Tizazu Gebre
Summary: This study documents the use of traditional medicinal plants for human and livestock health in the Dawuro Zone of Ethiopia. The study found that there is a rich diversity of traditional medicinal plants used in the study area, with the majority being sourced from natural forests. The study also highlights the need for conservation intervention and sustainable utilization of these medicinal plants, as well as the integration of traditional medicine with modern healthcare systems in rural communities.
JOURNAL OF ETHNOBIOLOGY AND ETHNOMEDICINE
(2022)
Article
Pharmacology & Pharmacy
Methee Phumthum, Varangrat Nguanchoo, Henrik Balslev
Summary: The COVID-19 pandemic has caused severe global problems and there is uncertainty about its duration. Traditional medicinal plants used by Hmong and Karen in Thailand for treating mild COVID-19 symptoms were identified. 491 plant species were used to treat various symptoms, with 60 species most commonly mentioned for treatments of mild COVID-19 symptoms.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Plant Sciences
Andreas M. Savvides, Constantina Stavridou, Sotiroula Ioannidou, Christos Zoumides, Andreas Stylianou
Summary: This research aims to document and analyze the traditional uses of medicinal and aromatic plants in the Troodos mountains. Data on 160 plant taxa and their traditional uses were collected through interviews and analyzed quantitatively. The results reveal a deep connection between the people of Troodos and the plants of the area.
Article
Pharmacology & Pharmacy
Zhuo Cheng, Xian Hu, Xiaoping Lu, Qiong Fang, Yuan Meng, Chunlin Long
Summary: The Dulong ethnic group in Southwest China has rich traditional knowledge about medicinal plants, but this knowledge is being threatened in recent decades. They mainly use whole plants for medicine preparation, with decoction being the most common method and oral administration the most frequent route. Their highest focus in plant usage is on the circulatory system, immune system, and nervous system.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Plant Sciences
Chabaco Armijos, Jorge Ramirez, Giovanni Vidari
Summary: This article summarizes the rich flora of Ecuador, which is one of the richest in Latin America and the world. It also emphasizes the importance of conducting extensive research on medicinal plants to preserve traditional knowledge and provide economic and social benefits to the indigenous communities.
Review
Plant Sciences
Gugulethu P. Khumalo, Ben Erik Van Wyk, Yunjiang Feng, Ian E. Cock
Summary: Traditional medicinal plants from southern Africa are commonly used to treat inflammation and pain-related ailments, but there is still a lack of research on their anti-inflammatory properties and further studies are needed.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Antonio Falasca, Claudio Caprari, Vincenzo De Felice, Paola Fortini, Gabriella Saviano, Franco Zollo, Maria Iorizzi
BIOCHEMICAL SYSTEMATICS AND ECOLOGY
(2016)
Article
Forestry
Romeo Di Pietro, Antonio Luca Conte, Piera Di Marzio, Paola Fortini, Emmanuele Farris, Lorenzo Gianguzzi, Markus Mueller, Leonardo Rosati, Giovanni Spampinato, Oliver Gailing
Summary: The study analyzed the molecular diversity of deciduous pubescent oaks from Calabria, Sicily, and Sardinia, revealing high genetic diversity within populations but weak genetic separation between them, with a weak positive correlation between genetic and geographic distance. The genetic assignment analysis did not correspond to the taxonomic classification of the populations, suggesting that the current taxonomic classification may not be accurate based on molecular analyses.
EUROPEAN JOURNAL OF FOREST RESEARCH
(2021)
Article
Plant Sciences
Bruno Paura, Piera Di Marzio, Giovanni Salerno, Elisabetta Brugiapaglia, Annarita Bufano
Summary: Despite the abundance of data on Wild Edible Plants (WEPs) published in Italy, there is a lack of a comprehensive knowledge framework database. AlimurgITA was designed to address this gap, with 1103 WEP taxa already entered in the database, representing 13.09% of Italian flora. The most common family is Asteraceae.
Article
Biochemistry & Molecular Biology
Claudio Caprari, Francesca Fantasma, Fabio Divino, Antonio Bucci, Maria Iorizzi, Gino Naclerio, Giancarlo Ranalli, Gabriella Saviano
Summary: The study compared the chemical composition and antibacterial activity of essential oils from dried and fresh lavender flowers grown in central Italy, finding similar compositions and antimicrobial effects against E. coli and B. subtilis. The oils also exhibited significant antioxidant and antifungal activities, showing potential for controlling post-harvest diseases in fruits and vegetables and biodeterioration in artistic wood paintings from the 19th century.
Article
Biochemistry & Molecular Biology
Anella Saviano, Simona De Vita, Maria Giovanna Chini, Noemi Marigliano, Gianluigi Lauro, Gian Marco Casillo, Federica Raucci, Maria Iorizzi, Robert Klaus Hofstetter, Katrin Fischer, Andreas Koeberle, Oliver Werz, Francesco Maione, Giuseppe Bifulco
Summary: Tanshinone IIA (TIIA) and cryptotanshinone (CRY) were found to inhibit the COX-2/mPGES-1/EP3 pathway, suggesting their potential as anti-inflammatory and anti-thrombotic agents.
Article
Biology
Bruno Paura, Piera Di Marzio
Summary: In 1766, Giovanni Targioni Tozzetti described wild and cultivated plant species that could be used during famine to increase flour or vegetable mass in bread making for the Grand Duchy of Tuscany. By researching and matching vernacular names with current nomenclature, an alimurgic flora repertoire based on his work was created and compared with the AlimurgITA database of wild edible plants used in Italy. Additionally, toxic plants useful for bread making were identified and their toxicity, past and current usage, and geographical distribution in Italy were examined.
Article
Plant Sciences
Paola Fortini, Piera Di Marzio, Antonio Luca Conte, Gaby Antonecchia, Elisa Proietti, Romeo Di Pietro
Summary: This study analyzed seven pubescent oak populations in central Italy from a coenological, morphological, and molecular perspective. The results showed that leaf pubescence was the only discriminating factor among the leaf morphological traits considered. Genetic analyses did not reveal significant differences or any ecological-altitudinal vicariance between Quercus pubescens and Q. virgiliana.
Article
Biochemistry & Molecular Biology
Claudio Caprari, Francesca Fantasma, Pamela Monaco, Fabio Divino, Maria Iorizzi, Giancarlo Ranalli, Fausto Fasano, Gabriella Saviano
Summary: The chemical composition of lavender essential oils from different geographical areas was analyzed, and their antifungal and antioxidant activities were evaluated. The results showed significant variability in the main components of the oils and different toxicity patterns against various fungal species. The potential application of lavender essential oils in the preservation of wooden artworks was also assessed.
Article
Biodiversity Conservation
Amara Noor Hussain, Jeroen Geuens, Ann Vermoesen, Mamoona Munir, Duilio Iamonico, Piera Di Marzio, Paola Fortini
Summary: This study investigated the composition and content of seed oil in six wild Amaranthus species in Italy. The results showed that the oil and squalene content of the Amaranthus species were influenced by the collection site and seed size. The smallest seeds had the highest oil and squalene percentages, while the samples growing at lower altitudes had the highest concentration of fatty acids.
Article
Multidisciplinary Sciences
Elisa Proietti, Leonardo Filesi, Piera Di Marzio, Romeo Di Pietro, Rizzieri Masin, Antonio Luca Conte, Paola Fortini
Summary: The study aimed to verify the presence of Quercus dalechampii in the Euganean Hills and identify diagnostic morphological traits to distinguish it from Quercus petraea and Quercus pubescens. Using phytosociological approach, forest stands were sampled and analyzed for ecological features. Results showed no confirmation of a third oak species in the study area apart from Quercus petraea and Quercus pubescens.
RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI
(2021)
Article
Plant Sciences
Romeo Di Pietro, Antonio Luca Conte, Piera Di Marzio, Lorenzo Gianguzzi, Giovanni Spampinato, Orazio Caldarella, Paola Fortini
Article
Multidisciplinary Sciences
Emanuela Carli, Eleonora Giarrizzo, Sabina Burrascano, Marta Alos, Eva Del Vico, Piera Di Marzio, Laura Facioni, Carmen Giancola, Barbara Mollo, Bruno Paura, Giovanni Salerno, Laura Zavattero, Carlo Blasi
RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI
(2018)
Article
Environmental Studies
Michele Minotti, Carmen Giancola, Piera Di Marzio, Paolo Di Martino
Correction
Plant Sciences
Lingmiao Wen, Tinglan Zhang, Fangfang Chen, Lin Hu, Chongyang Dou, Xian Ding, Alvin Altamirano, Guihua Wei, Zhiyong Yan
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Qing Tang, Mengfei Xu, Shunqin Long, Yaya Yu, Changju Ma, Rui Wang, Jing Li, Xi Wang, Fang Fang, Ling Han, Wanyin Wu, Sumei Wang
Summary: This study demonstrates that Fuzheng Kang-Ai (FZKA) decoction can inhibit the cell growth, proliferation, and invasion of lung adenocarcinoma (LUAD) and reverse the acquired resistance of gefitinib. FZKA exerts its effects by regulating the p-ERK1/2-EZH2-Snail/EGFR signaling pathway.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Xiang Zhao, Xianrun Hu, Qi Xie, Shenglan Qi, Zedong Xiang, Xin Sun, Zhejun Xie, Rui Dang, Limei Zhou, Wei Liu, Xuemei Cheng, Changhong Wang
Summary: This study investigated the effects of Fufangmuniziqi formula (FFMN) on Alzheimer's disease (AD) and the role of alkaloids, flavonoids, and saponins in the process. The results showed that FFMN improved cognitive and memory impairment in the AD mouse model. Alkaloids enhanced the cholinergic system, while flavonoids and saponins attenuated neuroinflammation and oxidative stress. These findings suggest that the combination of alkaloid, flavonoid, and saponin fractions derived from FFMN is a promising anti-AD agent.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Bangjian Dong, Ying Peng, Mengyue Wang, Chongsheng Peng, Xiaobo Li
Summary: This study elucidated the tissue distribution and excretion characteristics of the non-polysaccharide components of Sijunzi decoction in rats with spleen deficiency syndrome. It proposed new insights into the rationality of the compatibility of Sijunzi decoction.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jung-Seop Kim, Man-Gi Kim, Ji Eun Ryu, Ye-Been Lee, Quan Feng Liu, Kwang Ki Kim, Seung-Hun Cho, Sung Joon Shin, Byung-Soo Koo, Hyung-Kyoon Choi
Summary: Co-treatment with WCW and donepezil shows promise in improving cognitive function and serum metabolic profiles in a scopolamine-induced AD model. This combination therapy may reduce tyrosine and methionine levels, enhancing cognitive function by mitigating known risk factors for AD. The study provides a foundation for developing other bioactive compounds in AD treatment.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Kuang-Hsing Chiang, Tain-Junn Cheng, Wei-Chih Kan, Hsien-Yi Wang, Jui-Chen Li, Yan-Ling Cai, Chia-Hui Cheng, Yi-Chien Liu, Chia-Yu Chang, Jiunn-Jye Chuu
Summary: The ethanolic extract of Orthosiphon aristatus (OA) demonstrated an improving effect on memory and could serve as a potential therapeutic target for the treatment of neurodegenerative diseases like Alzheimer's disease (AD).
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Meryem Tourabi, Asmae EL Ghouizi, Ghizlane Nouioura, Khaoula Faiz, Hind Elfatemi, Karima El-yagoubi, Badiaa Lyoussi, Elhoussine Derwich
Summary: Mentha longifolia is a native plant in Morocco, traditionally used to treat various diseases. This study analyzed the phytochemical profile of the aqueous extract of M. longifolia and evaluated its acute and subacute toxicity in mice. The results showed that M. longifolia extract is rich in phenolic compounds and has no observed toxicity up to a certain dosage limit.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yue Zhang, Liang Li, Tao Chai, Han Xu, Hong-yan Du, Yan Jiang
Summary: Mulberry leaf multi-components (MMC) have hypoglycemic effects and can improve insulin resistance by activating the PI-3K/Akt signaling pathway. These findings highlight the multi-component, multi-target, and combined effects of MMC, and suggest it may be further developed as a hypoglycemic drug.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Correction
Plant Sciences
Shan Luo, Yuanchun Chen, Ruoxi Zhao, Donglai Ma, Yanmeng Zhao, Ying Zhang, Jianming Jiang, Wentao Yu
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Nittaya Chansiw, Pattranuch Chusri, Siwaporn Praman, Thaneeya Hawiset, Wannisa Sukhorum, Sorraya Champakam, Rawiwan Charoensup
Summary: This study evaluates the anti-inflammatory activity of Prabchompoothaweep (PCT) extract in an animal model. The results show that PCT significantly reduces inflammation and pro-inflammatory cytokines in acute and sub-acute inflammation. These findings suggest that PCT could be a new option for the treatment of inflammatory diseases.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yanting Wang, Guoqiang Liang, Wei Mu, Shu Sun, Xuanyi Chen, Xiaofeng Xu
Summary: Bushen Tianjing Recipe (BTR) is a tonic-kidney formula of Traditional Chinese Medicine (TCM) with good therapeutic effects in clinical settings. The aim of this study was to investigate the effect of BTR on women's reproductive system by incubating miR-23a-induced KGN cells.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jiayi Zhi, Li Yin, Zhoudong Zhang, Yaozhong Lv, Fan Wu, Yang Yang, Enming Zhang, Huanqiu Li, Ning Lu, Mengze Zhou, Qinghua Hu
Summary: This study verified the pharmacodynamics of JSW in the treatment of AD and explored its potential mechanism using network pharmacology, molecular docking, and experimental validation.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Review
Plant Sciences
Elizabeth Syowai Mutinda, Dong-Juan Zhang, Felix Wambua Muema, Elijah Mbandi Mkala, Emmanuel Nyongesa Waswa, Wyclif Ochieng Odago, Clintone Onyango Ochieng, Moses Kirega Gichua, John Kamau Muchuku, Elizabeth Kamande, Guang-Wan Hu
Summary: This article reviews the traditional uses, pharmacological properties, and phytoconstituents of Balanophora species, revealing that they contain diverse chemical compounds with interesting biological activities. However, research on many species in this genus is still lacking.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Luqi Cai, Yu Chen, Huizhong Xue, Yimeng Yang, Yuqi Wang, Junhe Xu, Chunyan Zhu, Long He, Yonghua Xiao
Summary: Salvia miltiorrhiza Bunge (SM) has been proven to have potential therapeutic effects for diabetic nephropathy (DN) through its multi-component, multi-target, and multi-pathway pharmacological effects.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Chao Wang, Rui-Jia Fu, Ding-Qiao Xu, Qian Zuo, Ji-Ping Liu, Yu-Ping Tang
Summary: This study aimed to explore the hepatoprotective effects of Shicao on CCl4-induced acute liver injury. A rat model of acute liver injury was established and liver function indices were assessed. Untargeted metabolomics was conducted to identify differential metabolites. Network pharmacology was used to construct a network of metabolite-reaction-enzyme-gene constituents, and key components and hub genes were screened. Shicao showed hepatoprotective effects against acute liver injury in rats.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)