Proteomic analysis of MSC‐derived apoptotic vesicles identifies Fas inheritance to ameliorate haemophilia a via activating platelet functions

Circulating extracellular vesicles are endowed with enhanced procoagulant activity in SARS-CoV-2 infection

(2021) Carolina Balbi et al.   EBioMedicine

Apoptotic Extracellular Vesicles Ameliorate Multiple Myeloma by Restoring Fas-Mediated Apoptosis

(2021) Juan Wang et al.   ACS Nano

Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker

(2021) Fernanda G. Kugeratski et al.   NATURE CELL BIOLOGY

Clinical burden of hemophilia in older adults: Beyond bleeding risk

(2021) Mohammad Hassan Hodroj et al.   BLOOD REVIEWS

Hemophilia as a blueprint for gene therapy

(2021) Margaret V. Ragni   SCIENCE

Influence of nanoparticles on the haemostatic balance: between thrombosis and haemorrhage

(2021) Huong D. N. Tran et al.   Biomaterials Science

Apoptotic cell-derived exosomes: messages from dying cells

(2020) Ramesh Kakarla et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Hemophilia therapy: the future has begun

(2020) Pier Mannuccio Mannucci   HAEMATOLOGICA

LAMA2 regulates the fate commitment of mesenchymal stem cells via hedgehog signaling

(2020) Yuan Zhu et al.   Stem Cell Research & Therapy

Chimeric apoptotic bodies functionalized with natural membrane and modular delivery system for inflammation modulation

(2020) Geng Dou et al.   Science Advances

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

(2020) Eugenio D. Hottz et al.   BLOOD

Treatment of Hemophilia — More Amazing Progress

(2020) Pier M. Mannucci   NEW ENGLAND JOURNAL OF MEDICINE

Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p

(2020) Mingyi Qu et al.   Nature Communications

Extracellular Vesicles Derived From Apoptotic Cells: An Essential Link Between Death and Regeneration

(2020) Maojiao Li et al.   Frontiers in Cell and Developmental Biology

Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models

(2019) Anne-Laure Papa et al.   Science Translational Medicine

Proteomic profiling and integrated analysis with transcriptomic data bring new insights in the stress responses of Kluyveromyces marxianus after an arrest during high-temperature ethanol fermentation

(2019) Pengsong Li et al.   Biotechnology for Biofuels

Manufacturing of primed mesenchymal stromal cells for therapy

(2019) James Q. Yin et al.   Nature Biomedical Engineering

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

The Necrobiology of Mesenchymal Stromal Cells Affects Therapeutic Efficacy

(2019) Daniel J. Weiss et al.   Frontiers in Immunology

Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles in vitro

(2019) Ivan K. H. Poon et al.   Journal of Extracellular Vesicles

Platelets and platelet extracellular vesicles in hemostasis and sepsis

(2019) Elizabeth W J Kerris et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Tissue-Engineered Bone Immobilized with Human Adipose Stem Cells-Derived Exosomes Promotes Bone Regeneration

(2018) Wenyue Li et al.   ACS Applied Materials & Interfaces

Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry

(2018) Ye Tian et al.   ACS Nano

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Targeting anticoagulant protein S to improve hemostasis in hemophilia

(2018) Raja Prince et al.   BLOOD

Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factors

(2018) Dawei Liu et al.   CELL RESEARCH

Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities

(2018) Jacques Galipeau et al.   Cell Stem Cell

NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis

(2018) Jianlin Qiao et al.   HAEMATOLOGICA

Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases

(2018) Yufang Shi et al.   Nature Reviews Nephrology

The Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to accelerate wound healing

(2018) Xiaoxing Kou et al.   Science Translational Medicine

NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis

(2018) Jianlin Qiao et al.   HAEMATOLOGICA

Platelet-RBC interaction mediated by FasL/FasR induces procoagulant activity important for thrombosis

(2018) Christoph Klatt et al.   JOURNAL OF CLINICAL INVESTIGATION

New Therapies for hemophilia

(2018) Angela C. Weyand et al.   BLOOD

Platelet activity and hypercoagulation in type 2 diabetes

(2018) Lesha Pretorius et al.   Cardiovascular Diabetology

Molecular mechanisms of biogenesis of apoptotic exosome-like vesicles and their roles as damage-associated molecular patterns

(2018) Soo Jeong Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Do methodological differences account for the current controversy on tissue factor expression in platelets?

(2017) Marta Brambilla et al.   PLATELETS

Platelets and hemophilia: A review of the literature

(2017) Julia Riedl et al.   THROMBOSIS RESEARCH

Disassembly of the Dying: Mechanisms and Functions

(2017) Georgia K. Atkin-Smith et al.   TRENDS IN CELL BIOLOGY

Heparin improves BMSC cell therapy: Anticoagulant treatment by heparin improves the safety and therapeutic effect of bone marrow-derived mesenchymal stem cell cytotherapy

(2017) Li Liao et al.   Theranostics

High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention

(2016) Jun-Jie Zhang et al.   BMC Cardiovascular Disorders

Discovery of potential colorectal cancer serum biomarkers through quantitative proteomics on the colonic tissue interstitial fluids from the AOM–DSS mouse model

(2016) Yang Wang et al.   Journal of Proteomics

Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor

(2016) Qingshan Fu et al.   MOLECULAR CELL

Platelet Activation: The Mechanisms and Potential Biomarkers

(2016) Seong-Hoon Yun et al.   Biomed Research International

Extracellular Vesicles: Evolving Factors in Stem Cell Biology

(2016) Muhammad Nawaz et al.   Stem Cells International

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets

(2015) Toshihiro Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Tissue Factor in Atherothrombosis and Coronary Artery Disease: Insights into Platelet Tissue Factor

(2015) Vincenzo Toschi et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

(2015) Georgia K. Atkin-Smith et al.   Nature Communications

Mesenchymal Stem Cells Prevent Hypertrophic Scar Formation via Inflammatory Regulation when Undergoing Apoptosis

(2014) Shiyu Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Proteogenomic characterization of human colon and rectal cancer

(2014) Bing Zhang et al.   NATURE

Unexpected link between an antibiotic, pannexin channels and apoptosis

(2014) Ivan K. H. Poon et al.   NATURE

The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine

(2013) Paolo Bianco et al.   NATURE MEDICINE

Human platelets do not express tissue factor

(2013) Bjarne Østerud et al.   THROMBOSIS RESEARCH

Platelet tissue factor is not expressed transiently after platelet activation

(2012) B. A. Bouchard et al.   BLOOD

Activation state of platelets in experimental severe hemophilia A

(2012) M. Teyssandier et al.   HAEMATOLOGICA

Strategy for SRM-based Verification of Biomarker Candidates Discovered by iTRAQ Method in Limited Breast Cancer Tissue Samples

(2012) Satoshi Muraoka et al.   JOURNAL OF PROTEOME RESEARCH

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease

(2011) Terri A Addona et al.   NATURE BIOTECHNOLOGY

Tissue factor expression on platelets is a dynamic event

(2010) M. Camera et al.   BLOOD

No evidence for tissue factor on platelets

(2010) B. A. Bouchard et al.   BLOOD

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY