Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases

Structure and function of carbonic anhydrases

(2016) C. T. Supuran   BIOCHEMICAL JOURNAL

The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes

(2016) Cem Yamali et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol

(2016) Halise Inci Gul et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

A novel curcumin-like dienone induces apoptosis in triple-negative breast cancer cells

(2016) Elisa Robles-Escajeda et al.   CELLULAR ONCOLOGY

Mannich bases in medicinal chemistry and drug design

(2015) Gheorghe Roman   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anti-cancer chalcones: Structural and molecular target perspectives

(2015) Debarshi Kar Mahapatra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2,3-dihydroinden-1-one and evaluation of their cytotoxicities

(2015) Mehtap Tugrak et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

How many carbonic anhydrase inhibition mechanisms exist?

(2015) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Recent developments in biological activities of chalcones: A mini review

(2014) Parvesh Singh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one and its aminomethyl derivatives

(2014) Kadir Ozden Yerdelen et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Phenols incorporating 2- or 3-pyridyl-ethenylcarbonyl and tertiary amine moieties strongly inhibitSaccharomyces cerevisiaeβ-carbonic anhydrase

(2013) Sinan Bilginer et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

1-(3-Aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones: A novel group of tumour-selective cytotoxins

(2012) Sinan Bilginer et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Development of Potent Carbonic Anhydrase Inhibitors Incorporating Both Sulfonamide and Sulfamide Groups

(2012) Katia D'Ambrosio et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I–XIV with a series of natural product polyphenols and phenolic acids

(2010) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of simple methoxylated chalcones as anticancer, anti-inflammatory and antioxidant agents

(2009) Babasaheb P. Bandgar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins

(2009) Alfonso Maresca et al.   JOURNAL OF MEDICINAL CHEMISTRY

Microwave-Assisted Mannich Reaction of 2-Hydroxy-chalcones

(2009) Xiaowu Dong et al.   SYNTHETIC COMMUNICATIONS

In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II

(2008) Esra Bayram et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cytotoxic activity of 4′-hydroxychalcone derivatives against Jurkat cells and their effects on mammalian DNA topoisomerase I

(2008) Halise Inci Gul et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY