Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis

Integrin α11β1 in tumor fibrosis: more than just another cancer-associated fibroblast biomarker?

(2022) Cédric Zeltz et al.   Journal of Cell Communication and Signaling

Matrix Effectors in the Pathogenesis of Keratinocyte-Derived Carcinomas

(2022) Rafaela-Maria Kavasi et al.   Frontiers in Medicine

Verteporfin inhibits the persistent fibrotic phenotype of lesional scleroderma dermal fibroblasts

(2021) Xu Shi-wen et al.   Journal of Cell Communication and Signaling

Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer

(2021) Yang Chen et al.   CANCER CELL

Implication of cancer associated fibroblast subtypes on cancer pathogenesis, prognosis, and immunotherapy resistance

(2021) Phillip M Galbo et al.   CLINICAL CANCER RESEARCH

Deletion of Col15a1 Modulates the Tumour Extracellular Matrix and Leads to Increased Tumour Growth in the MMTV-PyMT Mouse Mammary Carcinoma Model

(2021) Guillermo Martínez-Nieto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clinical and therapeutic relevance of cancer-associated fibroblasts

(2021) Yang Chen et al.   Nature Reviews Clinical Oncology

Myofibroblast transcriptome indicates SFRP2hi fibroblast progenitors in systemic sclerosis skin

(2021) Tracy Tabib et al.   Nature Communications

Single-cell analysis reveals the pan-cancer invasiveness-associated transition of adipose-derived stromal cells into COL11A1-expressing cancer-associated fibroblasts

(2021) Kaiyi Zhu et al.   PLoS Computational Biology

Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion

(2021) Xiujie Sun et al.   NATURE

Immune Modulatory Properties of Collagen in Cancer

(2021) Anne Mette Askehøj Rømer et al.   Frontiers in Immunology

Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma

(2020) Andrew L. Ji et al.   CELL

Integrin α11 in pancreatic stellate cells regulates tumor stroma interaction in pancreatic cancer

(2019) Jonas Schnittert et al.   FASEB JOURNAL

LOXL1 Is Regulated by Integrin α11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity

(2019) Cédric Zeltz et al.   Cancers

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

(2019) Ela Elyada et al.   Cancer Discovery

Stromal integrin α11 regulates PDGFRβ signaling and promotes breast cancer progression

(2019) Irina Primac et al.   JOURNAL OF CLINICAL INVESTIGATION

Single-cell RNA sequencing reveals stromal evolution into LRRC15+ myofibroblasts as a determinant of patient response to cancer immunotherapy

(2019) Claudia X Dominguez et al.   Cancer Discovery

The extracellular matrix as a key regulator of intracellular signalling networks

(2018) Jordan F Hastings et al.   BRITISH JOURNAL OF PHARMACOLOGY

Analysis of cancer-associated fibroblasts and the epithelial-mesenchymal transition in cutaneous basal cell carcinoma, squamous cell carcinoma, and malignant melanoma

(2018) Kousuke Sasaki et al.   HUMAN PATHOLOGY

Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

(2018) Michael Bartoschek et al.   Nature Communications

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

(2017) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

New perspectives on role of tumor microenvironment in progression of cutaneous squamous cell carcinoma

(2016) Liisa Nissinen et al.   CELL AND TISSUE RESEARCH

The integrin–collagen connection – a glue for tissue repair?

(2016) Cédric Zeltz et al.   JOURNAL OF CELL SCIENCE

Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression

(2016) Himalaya Parajuli et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice

(2015) Yong Ryoul Yang et al.   DIABETOLOGIA

Reduced Granulation Tissue and Wound Strength in the Absence of α11β1 Integrin

(2015) Jan-Niklas Schulz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer

(2015) R Navab et al.   ONCOGENE

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

(2014) Berna C. Özdemir et al.   CANCER CELL

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Fibroblast heterogeneity in the cancer wound

(2014) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The potential for targeting extracellular LOX proteins in human malignancy

(2013) Janine Erler et al.   OncoTargets and Therapy

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma

(2012) Vladimir Ratushny et al.   JOURNAL OF CLINICAL INVESTIGATION

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Cell-Extracellular Matrix Interactions in Normal and Diseased Skin

(2011) F. M. Watt et al.   Cold Spring Harbor Perspectives in Biology

Collagen XV Is Necessary for Modeling of the Extracellular Matrix and Its Deficiency Predisposes to Cardiomyopathy

(2010) Karolina Rasi et al.   CIRCULATION RESEARCH

Non-melanoma skin cancer

(2010) Vishal Madan et al.   LANCET

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications

(2009) Erika L Abel et al.   Nature Protocols

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma

(2008) Mert Erkan et al.   Clinical Gastroenterology and Hepatology