HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling

STAT1 and STAT3 Exhibit a Crosstalk and Are Associated with Increased Inflammation in Hepatocellular Carcinoma

(2022) Carolin Ploeger et al.   Cancers

The Effects and Underlying Mechanisms of Hepatitis B Virus X Gene Mutants on the Development of Hepatocellular Carcinoma

(2022) Rui Pu et al.   Frontiers in Oncology

Epidemiological Characteristics of Primary Liver Cancer in Mainland China From 2003 to 2020: A Representative Multicenter Study

(2022) Jiansheng Lin et al.   Frontiers in Oncology

Increased infiltration of regulatory T cells in hepatocellular carcinoma of patients with hepatitis B virus pre-S2 mutant

(2021) Chiao-Fang Teng et al.   Scientific Reports

IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation

(2021) Roberta Gonnella et al.   Biomedicines

Prognostic significance of phosphoglycerate dehydrogenase in breast cancer

(2021) Muthukrishnan Chandrika et al.   BREAST CANCER RESEARCH AND TREATMENT

Clinical implications on HBV preS/S mutations and the effects of preS2 deletion on mitochondria, liver fibrosis, and cancer development

(2021) Yuh‐Jin Liang et al.   HEPATOLOGY

Nucleotide variants in hepatitis B virus preS region predict the recurrence of hepatocellular carcinoma

(2021) Xi Chen et al.   Aging-US

The ever‐increasing importance of cancer as a leading cause of premature death worldwide

(2021) Freddie Bray et al.   CANCER

Trends in cancer mortality in China from 2004 to 2018: A nationwide longitudinal study

(2021) Dongming Jiang et al.   Cancer Communications

Global, regional and national burden of primary liver cancer by subtype

(2021) Harriet Rumgay et al.   EUROPEAN JOURNAL OF CANCER

LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity

(2020) Hui Wang et al.   EXPERIMENTAL CELL RESEARCH

ERO1L promotes IL6/sIL6R signaling and regulates MUC16 expression to promote CA125 secretion and the metastasis of lung cancer cells

(2020) Yuanyuan lei et al.   Cell Death & Disease

Association of the Hepatitis B Virus Large Surface Protein with Viral Infectivity and Endoplasmic Reticulum Stress-mediated Liver Carcinogenesis

(2020) Wei-Ling Lin et al.   Cells

Compartmentalized evolution of hepatitis B virus contributes differently to the prognosis of hepatocellular carcinoma

(2020) Jianhua Yin et al.   CARCINOGENESIS

WNT4 secreted by tumor tissues promotes tumor progression in colorectal cancer by activation of the Wnt/β-catenin signalling pathway

(2020) Dongmei Yang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Hepatitis B virus pre‐S region: Clinical implications and applications

(2020) Huizhen Sun et al.   REVIEWS IN MEDICAL VIROLOGY

Blockage of ETS homologous factor inhibits the proliferation and invasion of gastric cancer cells through the c-Met pathway

(2020) Meng-Li Gu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Increased Expression of Programmed Death Ligand 1 in Hepatocellular Carcinoma of Patients with Hepatitis B Virus Pre-S2 Mutant

(2020) Chiao-Fang Teng et al.   Journal of Hepatocellular Carcinoma

Genetic polymorphisms predisposing the interleukin-6-induced APOBEC3B-UNG imbalance increase HCC risk via promoting the generation of APOBEC-signature HBV mutations

(2019) Wenbin Liu et al.   CLINICAL CANCER RESEARCH

Hepatic Stress Response in HCV Infection Promotes STAT3-Mediated Inhibition of HNF4A-miR-122 Feedback Loop in Liver Fibrosis and Cancer Progression

(2019) Aydin et al.   Cancers

Prevalence of hepatocarcinoma-related hepatitis B virus mutants in patients in grey zone of treatment

(2019) Ana Isabel Gil-García et al.   WORLD JOURNAL OF GASTROENTEROLOGY

MUC13 promotes intrahepatic cholangiocarcinoma progression via EGFR/PI3K/AKT pathways

(2019) Pei Tiemin et al.   JOURNAL OF HEPATOLOGY

IRE1α‑XBP1 signaling pathway regulates IL‑6 expression and promotes progression of hepatocellular carcinoma

(2018) Peipei Fang et al.   Oncology Letters

Molecular analysis of Hepatitis B virus sub-genotypes and incidence of preS1/preS2 region mutations in HBV-infected Egyptian patients from Mansoura

(2017) Mohammed El-Mowafy et al.   JOURNAL OF MEDICAL VIROLOGY

Expression of a hepatitis B virus pre-S2 deletion mutant in the liver results in hepatomegaly and hepatocellular carcinoma in mice

(2017) Yuan-Chi Teng et al.   JOURNAL OF PATHOLOGY

Mutations in hepatitis B virus polymerase are associated with the postoperative survival of hepatocellular carcinoma patients

(2017) Fei Yin et al.   PLoS One

Hepatitis B Virus Combo Mutations Improve the Prediction and Active Prophylaxis of Hepatocellular Carcinoma: A Clinic-Based Cohort Study

(2015) J. Yin et al.   Cancer Prevention Research

VERSE: a novel approach to detect virus integration in host genomes through reference genome customization

(2015) Qingguo Wang et al.   Genome Medicine

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

(2014) Xi Chen et al.   NATURE

Epithelial-to-Mesenchymal Transition Activates PERK-eIF2  and Sensitizes Cells to Endoplasmic Reticulum Stress

(2014) Y.-x. Feng et al.   Cancer Discovery

Hypoxic Activation of the PERK/eIF2  Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3

(2013) H. Mujcic et al.   CLINICAL CANCER RESEARCH

Gene expression profiling-derived immunohistochemistry signature with high prognostic value in colorectal carcinoma

(2013) Wenjun Chang et al.   GUT

Effect of Antiviral Treatment With Nucleotide/Nucleoside Analogs on Postoperative Prognosis of Hepatitis B Virus–Related Hepatocellular Carcinoma: A Two-Stage Longitudinal Clinical Study

(2013) Jianhua Yin et al.   JOURNAL OF CLINICAL ONCOLOGY

Uracil DNA Glycosylase Counteracts APOBEC3G-Induced Hypermutation of Hepatitis B Viral Genomes: Excision Repair of Covalently Closed Circular DNA

(2013) Kouichi Kitamura et al.   PLoS Pathogens

Impact of hepatitis B virus (HBV) preS/S genomic variability on HBV surface antigen and HBV DNA serum levels

(2012) Teresa Pollicino et al.   HEPATOLOGY

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

A mutation in the interferon regulatory element of HBV may influence the response of interferon treatment in chronic hepatitis B patients

(2012) Jia-Jie Lu et al.   Virology Journal

D9S168 microsatellite alteration predicts a poor prognosis in patients with clear cell renal cell carcinoma and correlates with the down-regulation of protein tyrosine phosphatase receptor delta

(2011) Xiaopan Li et al.   CANCER

Hepatitis B Virus Large Surface Antigen Promotes Liver Carcinogenesis by Activating the Src/PI3K/Akt Pathway

(2011) H. Liu et al.   CANCER RESEARCH

Association Between the Various Mutations in Viral Core Promoter Region to Different Stages of Hepatitis B, Ranging of Asymptomatic Carrier State to Hepatocellular Carcinoma

(2010) Jianhua Yin et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Distribution and Hepatocellular Carcinoma-Related Viral Properties of Hepatitis B Virus Genotypes in Mainland China: A Community-Based Study

(2010) J. Yin et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma

(2010) Jianhua Yin et al.   JOURNAL OF GASTROENTEROLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma

(2009) Q. Gao et al.   CLINICAL CANCER RESEARCH

Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis

(2009) Jui-Chu Yang et al.   HEPATOLOGY