Pluripotency factors regulate the onset of Hox cluster activation in the early embryo

OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms

(2021) Giuliano G. Stirparo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactivation of the pluripotency program precedes formation of the cranial neural crest

(2021) Antoine Zalc et al.   SCIENCE

A single-cell molecular map of mouse gastrulation and early organogenesis

(2019) Blanca Pijuan-Sala et al.   NATURE

The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1

(2019) Julio Sainz de Aja et al.   EMBO JOURNAL

Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo

(2018) Carla Mulas et al.   DEVELOPMENT

Reassessing the Role of Hox Genes during Vertebrate Development and Evolution

(2018) Moisés Mallo   TRENDS IN GENETICS

Esrrb Complementation Rescues Development of Nanog -Null Germ Cells

(2018) Man Zhang et al.   Cell Reports

Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock

(2017) Jacqueline Deschamps et al.   GENES & DEVELOPMENT

Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation

(2017) Sharmistha Kundu et al.   MOLECULAR CELL

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells

(2017) Mariano Barbieri et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamic regulation of Nanog and stem cell-signaling pathways by Hoxa1 during early neuro-ectodermal differentiation of ES cells

(2017) Bony De Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells

(2017) Mariano Barbieri et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells

(2017) Hamish W King et al.   eLife

Oct4 Is a Key Regulator of Vertebrate Trunk Length Diversity

(2016) Rita Aires et al.   DEVELOPMENTAL CELL

Polarized regulatory landscape and Wnt responsiveness underlie Hox activation in embryos

(2016) Roel Neijts et al.   GENES & DEVELOPMENT

OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation

(2016) Zoltan Simandi et al.   MOLECULAR CELL

Resolving early mesoderm diversification through single-cell expression profiling

(2016) Antonio Scialdone et al.   NATURE

FourCSeq: analysis of 4C sequencing data

(2015) Felix A. Klein et al.   BIOINFORMATICS

Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells

(2015) E. Buitrago-Delgado et al.   SCIENCE

Reorganization of Enhancer Patterns in Transition from Naive to Primed Pluripotency

(2014) Christa Buecker et al.   Cell Stem Cell

Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst

(2014) G. C. Le Bin et al.   DEVELOPMENT

Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia

(2014) Daniela Piazzolla et al.   Nature Communications

Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci

(2014) Daan Noordermeer et al.   eLife

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Shadow enhancers flanking the HoxB cluster direct dynamic Hox expression in early heart and endoderm development

(2013) Christof Nolte et al.   DEVELOPMENTAL BIOLOGY

Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst

(2013) Tristan Frum et al.   DEVELOPMENTAL CELL

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages

(2013) Aliaksandra Radzisheuskaya et al.   NATURE CELL BIOLOGY

Oct4 Is Required ∼E7.5 for Proliferation in the Primitive Streak

(2013) Brian DeVeale et al.   PLoS Genetics

Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome

(2012) Abdenour Soufi et al.   CELL

The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression

(2012) R. Osorno et al.   DEVELOPMENT

A map of the cis-regulatory sequences in the mouse genome

(2012) Yin Shen et al.   NATURE

Robust 4C-seq data analysis to screen for regulatory DNA interactions

(2012) Harmen J G van de Werken et al.   NATURE METHODS

Pluripotency in the Embryo and in Culture

(2012) J. Nichols et al.   Cold Spring Harbor Perspectives in Biology

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Pluripotency Factors in Embryonic Stem Cells Regulate Differentiation into Germ Layers

(2011) Matt Thomson et al.   CELL

CTCF-mediated functional chromatin interactome in pluripotent cells

(2011) Lusy Handoko et al.   NATURE GENETICS

An Expanded Oct4 Interaction Network: Implications for Stem Cell Biology, Development, and Disease

(2010) Mercedes Pardo et al.   Cell Stem Cell

Hox Genes and Segmentation of the Hindbrain and Axial Skeleton

(2009) Tara Alexander et al.   Annual Review of Cell and Developmental Biology

Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells

(2009) P. Yuan et al.   GENES & DEVELOPMENT

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage

(2009) Leng-Siew Yeap et al.   Epigenetics & Chromatin

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

Systematic localization of oct-3/4 to the gastrulating mouse conceptus suggests manifold roles in mammalian development

(2008) Karen M. Downs   DEVELOPMENTAL DYNAMICS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols