Solvatochromic Cellular Stress Sensors Reveal the Compactness Heterogeneity and Dynamics of Aggregated Proteome

A Solvatochromic Fluorescent Probe Reveals Polarity Heterogeneity upon Protein Aggregation in Cells

(2021) Wang Wan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redesigning Solvatochromic Probe Laurdan for Imaging Lipid Order Selectively in Cell Plasma Membranes

(2020) Dmytro I. Danylchuk et al.   ANALYTICAL CHEMISTRY

Monitoring the Dynamics of Proteome Aggregation in Live Cells Using a Solubilized and Noncovalent Analogue of Fluorescent Protein Chromophores

(2020) Wang Wan et al.   ANALYTICAL CHEMISTRY

The proteostasis network and its decline in ageing

(2019) Mark S. Hipp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane-Permeant, Environment-Sensitive Dyes Generate Biosensors within Living Cells

(2019) Christopher J. MacNevin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment

(2019) Tze Cin Owyong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modulation of Fluorescent Protein Chromophores To Detect Protein Aggregation with Turn-On Fluorescence

(2018) Yu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A biosensor-based framework to measure latent proteostasis capacity

(2018) Rebecca J. Wood et al.   Nature Communications

Visualising the membrane viscosity of porcine eye lens cells using molecular rotors

(2017) Peter S. Sherin et al.   Chemical Science

A thiol probe for measuring unfolded protein load and proteostasis in cells

(2017) Moore Z. Chen et al.   Nature Communications

Rational Design of Push-Pull Fluorene Dyes: Synthesis and Structure-Photophysics Relationship

(2016) Janah Shaya et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fluorescence Lifetime Imaging of Membrane Lipid Order with a Ratiometric Fluorescent Probe

(2015) Vasyl Kilin et al.   BIOPHYSICAL JOURNAL

Fluorescence Turn-On Folding Sensor To Monitor Proteome Stress in Live Cells

(2015) Yu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorogenic Squaraine Dimers with Polarity-Sensitive Folding As Bright Far-Red Probes for Background-Free Bioimaging

(2014) Iuliia A. Karpenko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Environment-Sensing Merocyanine Dyes for Live Cell Imaging Applications

(2013) Christopher J. MacNevin et al.   BIOCONJUGATE CHEMISTRY

Dipolar 3-methoxychromones as bright and highly solvatochromic fluorescent dyes

(2012) Oleksandr A. Kucherak et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Fluorescence Ratiometry and Fluorescence Lifetime Imaging: Using a Single Molecular Sensor for Dual Mode Imaging of Cellular Viscosity

(2011) Xiaojun Peng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

(2011) Silvestre Alavez et al.   NATURE

Firefly luciferase mutants as sensors of proteome stress

(2011) Rajat Gupta et al.   NATURE METHODS

Fluorene Analogues of Prodan with Superior Fluorescence Brightness and Solvatochromism

(2010) Oleksandr A. Kucherak et al.   Journal of Physical Chemistry Letters

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE