Responses of regulatory and effector T-cells to low-dose interleukin-2 differ depending on the immune environment after allogeneic stem cell transplantation

Alternative donor transplantation for myelodysplastic syndromes: haploidentical relative and matched unrelated donors

(2021) Michael R. Grunwald et al.   Blood Advances

Harnessing Treg Homeostasis to Optimize Posttransplant Immunity: Current Concepts and Future Perspectives

(2021) Shuntaro Ikegawa et al.   Frontiers in Immunology

Composite GRFS and CRFS Outcomes After Adult Alternative Donor HCT

(2020) Rohtesh S. Mehta et al.   JOURNAL OF CLINICAL ONCOLOGY

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

(2020) Shogo Kumagai et al.   NATURE IMMUNOLOGY

Low-dose interleukin-2 as a modulator of Treg homeostasis after HSCT: current understanding and future perspectives

(2017) Ken-ichi Matsuoka   INTERNATIONAL JOURNAL OF HEMATOLOGY

Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets

(2017) Robert Zeiser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease

(2016) John Koreth et al.   BLOOD

Low-Dose Interleukin-2 Therapy Restores Regulatory T Cell Homeostasis in Patients with Chronic Graft-Versus-Host Disease

(2013) K.-i. Matsuoka et al.   Science Translational Medicine

High frequencies of CD62L+ naive regulatory T cells in allografts are associated with a low risk of acute graft-versus-host disease following unmanipulated allogeneic haematopoietic stem cell transplantation

(2011) S-Y. Lu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

(2011) John Koreth et al.   NEW ENGLAND JOURNAL OF MEDICINE

2-Gy whole-body irradiation significantly alters the balance of CD4+CD25−T effector cells and CD4+CD25+Foxp3+T regulatory cells in mice

(2010) Yanyan Qu et al.   Cellular & Molecular Immunology

Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice

(2010) Michio Tomura et al.   JOURNAL OF CLINICAL INVESTIGATION

Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment after experimental HCT

(2008) A. L. Bayer et al.   BLOOD

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

(2008) B. E. Anderson et al.   BLOOD