Article
Geriatrics & Gerontology
Krystal M. Kirby, Sreekrishna Pillai, Robert M. Brouillette, Jeffrey N. Keller, Alyssa N. De Vito, John P. Bernstein, Arend W. A. Van Gemmert, Owen T. Carmichael
Summary: This study found that brain functioning, motor task, and cognitive task performance in challenging dual-task conditions all contribute to the risk of falling among older adults. Multiple factors are involved in determining fall characteristics.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Public, Environmental & Occupational Health
Mariana Wingood, Elizabeth Peterson, Christopher Neville, Jennifer L. Vincenzo
Summary: This study developed a screening tool for identifying feet- and footwear-related influences on fall risk among community-dwelling older adults. The tool was evaluated and refined in two phases, resulting in a 20-item screening tool with high face and content validity.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Medicine, General & Internal
Larissa Donatoni da Silva, Agnes Shiel, Caroline McIntosh
Summary: Pilates may be effective in decreasing the risk of falls in older adults. Pilates intervention was found to improve functional mobility, mobility, gait, fear of falling and postural stability and therefore there is some evidence to suggest that Pilates reduces certain risk factors for falls in healthy older adults. However, there is an absence of high-quality evidence in regards to the impact of Pilates on reducing falls and further robust RCTs are needed.
FRONTIERS IN MEDICINE
(2021)
Article
Biophysics
Arian Vistamehr, Richard R. Neptune
Summary: Older adults exhibit poorer mediolateral balance control compared to younger adults during walking, as indicated by a significantly higher range of frontal-plane angular momentum. This difference is attributed to wider foot placement and higher hip abduction moment in older adults, emphasizing the importance of proper weight transfer mechanisms and hip abductor force production for maintaining mediolateral balance.
JOURNAL OF BIOMECHANICS
(2021)
Article
Geriatrics & Gerontology
Christina Wapp, Emmanuel Biver, Serge Ferrari, Philippe Zysset, Marcel Zwahlen
Summary: The aim of this study was to develop a statistical model to predict future fall rates in older adults using personalized risk predictors. The results showed that the number of prior falls was a strong risk factor, with individuals who have experienced three or more falls being more likely to fall multiple times again.
Article
Geriatrics & Gerontology
Kevin A. Kerber, Ran Bi, Lesli E. Skolarus, James F. Burke
Summary: This study aimed to characterize trajectories in physical performance over time and determine if these trajectories could improve fall prediction. The results showed that the trajectory of physical performance did not meaningfully improve fall prediction from a baseline physical performance assessment.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Review
Orthopedics
Humberto Omana, Kari Bezaire, Kyla Brady, Jayme Davies, Nancy Louwagie, Sean Power, Sydney Santin, Susan W. Hunter
Summary: The systematic review on the falls-related diagnostic test properties of the Functional Reach Test, single-leg stance test, and Tinetti Performance-Oriented Mobility Assessment in older adults found that these clinical tests of balance demonstrated an overall low diagnostic accuracy and were unable to correctly identify fallers. Future research should focus on understanding the role of these clinical tests in the comprehensive assessment of falls risk in older adults.
Article
Geriatrics & Gerontology
Claire E. E. Adam, Annette L. L. Fitzpatrick, Cindy S. S. Leary, Anjum Hajat, Sindana D. D. Ilango, Christina Park, Elizabeth A. A. Phelan, Erin O. O. Semmens
Summary: This study aimed to evaluate the association between change in gait speed and falls among older adults, taking into account cognitive status. The results showed that a decline in gait speed was associated with an increased risk of falls, while an increase in gait speed was not. This highlights the importance of regularly checking gait speed to prevent falls, regardless of cognitive status.
Article
Health Care Sciences & Services
Byung-Kun Lee, Wi-Young So, Hyun-Joo Kang
Summary: This study investigated the associations between fall risk and previous fall events, physical fitness, and gait speeds in older adult women in Korea. The results showed that participants with higher Berg Balance Scale (BBS) scores had a lower incidence of falls and exhibited better physical fitness and gait speeds compared to those with lower scores.
Article
Chemistry, Multidisciplinary
Sofia Lampropoulou, Anthi Kellari, Vasiliki Sakellari
Summary: This study aimed to evaluate the effects of guidance delivery time on balance, gait, falls, and cognitive functions in older adults. The results showed that significant improvements were observed in all assessed variables regardless of the guidance delivery time. However, giving guidance in advance may have better effects on mental function and exercise adherence.
APPLIED SCIENCES-BASEL
(2023)
Review
Chemistry, Multidisciplinary
Hanatsu Nagano
Summary: Fall prevention is crucial in an ageing society for better health and sustainable healthcare systems. Minimum foot clearance and coefficient of friction are important factors in preventing trips and slips. Restoring balance and controlling dynamic balance are vital for preventing falls. Practical intervention strategies include footwear modification, exercise, and technological rehabilitation.
APPLIED SCIENCES-BASEL
(2022)
Article
Neurosciences
Jonathan S. Lee-Confer, Kornelia Kulig, Christopher M. Powers
Summary: The study found that arm motions play a role in the recovery of balance during a slip event, with the arm contralateral to the slipping foot being most important.
HUMAN MOVEMENT SCIENCE
(2022)
Article
Gerontology
N. J. Spokely, K. J. Weitzel, K. A. Miller, M. Novaes Oliveira, S. D. Ball, B. S. Baker
Summary: This study assessed the impact of the Stay Strong, Stay Healthy level two resistance training program on 406 older adults. The results showed improvement in physical function, including the 30-second sit-to-stand, timed-up-and-go, flexibility, and balance scores, after 8 weeks of training. The benefits were similar across different age groups and geographic locations.
JOURNAL OF APPLIED GERONTOLOGY
(2023)
Review
Geriatrics & Gerontology
Jens Eg Norgaard, Martin Gronbech Jorgensen, Jesper Ryg, Jane Andreasen, Mathias Brix Danielsen, Daniel Kjaergaard Steiner, Stig Andersen
Summary: This study found that gait adaptability training (GAT) significantly reduces the number of falls and prevents fall-related fractures in older community dwellers. GAT is a promising and feasible exercise modality, but high-quality studies are needed to support a robust conclusion.
Article
Geriatrics & Gerontology
Lloyd Chan, Carmen Herrera Arbona, Matthew Brodie, Stephen Lord
Summary: Digital gait biomarkers captured by a wrist-worn device can predict injurious falls in older people. These biomarkers can be integrated into fall prevention strategies and screening programs.
Article
Gerontology
Giulia Ogliari, Jesper Ryg, Karen Andersen-Ranberg, Lasse Lybecker Scheel-Hincke, Tahir Masud
Summary: The study found a significant association between neighbourhood characteristics and falls, with vandalism or crime being linked to increased fall risk. Other neighbourhood features such as cleanliness, sense of belonging, neighbor helpfulness, and service accessibility had no significant impact on fall risk.
EUROPEAN JOURNAL OF AGEING
(2022)
Review
Geriatrics & Gerontology
Lotta J. Seppala, Nellie Kamkar, Eveline P. van Poelgeest, Katja Thomsen, Joost G. Daams, Jesper Ryg, Tahir Masud, Manuel Montero-Odasso, Sirpa Hartikainen, Mirko Petrovic, Nathalie van der Velde
Summary: The effectiveness of medication review and deprescribing interventions as a single intervention in falls prevention is assessed in this study. The heterogeneity of the interventions prevents an accurate estimation of the exact effect. These interventions should be included in multimodal strategies rather than implemented as stand-alone strategies in falls prevention.
Editorial Material
Geriatrics & Gerontology
Jemima T. Collins, Rowan H. Harwood, Alison Cowley, Claudio Di Lorito, Eamonn Ferguson, Marcos F. Minicucci, Louise Howe, Tahir Masud, Giulia Ogliari, Rebecca O'Brien, Paula S. Azevedo, David A. Walsh, John R. F. Gladman
Summary: Pain is common in people with dementia and effective pain management is challenging due to cognitive and communication impairments. It is unclear which interventions are effective for pain management and behavioral symptoms in people with dementia. Personalized evaluation and mechanistic phenotyping could help identify underlying mechanisms and guide personalized intervention strategies. Central pain processing mechanisms may be particularly important in people with pain and dementia, and accommodating these mechanisms could alleviate both pain and dementia symptoms.
Article
Oncology
Gabor Liposits, Jesper Ryg, Halla Skuladottir, Stine B. Winther, Soren Moller, Eva Hofsli, Carl-Henrik Shah, Laurids ostergaard Poulsen, Ake Berglund, Camilla Qvortrup, Pia Osterlund, Bengt Glimelius, Halfdan Sorbye, Per Pfeiffer
Summary: This study explores the prognostic value of four functional status measures in vulnerable older patients with metastatic colorectal cancer (mCRC) receiving first-line palliative chemotherapy. The results show that ECOG performance status, frailty phenotype, G8, and VES-13 are all effective tools for assessing overall survival in these patients.
JOURNAL OF GERIATRIC ONCOLOGY
(2023)
Article
Pharmacology & Pharmacy
Camilla Lynnerup, Charlotte Rossing, Morten Sodemann, Jesper Ryg, Anton Pottegard, Dorthe Nielsen
Summary: Little is known about the combined effect of risk factors in patients with language barriers or dementia. This study aimed to investigate medication safety among older migrants with cognitive disorders. Eight interviews were conducted with patients and relatives, and three main themes were identified: potential threats to medication safety, communication challenges and lack of medication information, and everyday life with medication.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2023)
Article
Critical Care Medicine
Stine Hanson, Annmarie Lassen, Dorthe Nielsen, Jesper Ryg, Roberto Forero, Mikkel Brabrand
Summary: This study assessed the stability and recall of CPR preferences of older patients in the emergency department. The results showed that one-third of patients changed their preferences at one month follow-up, and only a minority were able to recall their preferences.
Article
Oncology
Laerke Kjaer Tolstrup, Helena Mogelbjerg Ditzel, Ann-Kristine Weber Giger, Trine Lembrecht Jorgensen, Jesper Ryg, Karin Brochstedt Dieperink
Summary: This study aimed to determine whether HRQoL findings truly reflect cancer disease and treatment. It found that for patients with severe comorbidity, HRQoL results often reflect the steady state of their disabling comorbidity.
JOURNAL OF GERIATRIC ONCOLOGY
(2023)
Article
Medicine, General & Internal
Jens Eg Norgaard, Stig Andersen, Jesper Ryg, Andrew James Thomas Stevenson, Jane Andreasen, Anderson Souza Oliveira, Mathias Brix Danielsen, Martin Gronbech Jorgensen
Summary: This study evaluated the effects of a 4-session treadmill perturbation-based balance training (PBT) intervention on daily-life fall rates among older adults. The results showed that the PBT intervention did not have a significant effect on daily-life fall rates, but there was a significant decrease in falls in the laboratory setting.
Article
Geriatrics & Gerontology
Thorbjorn Hougaard Mikkelsen, Jens Sondergaard, Niels Kristian Kjaer, Jesper Bo Nielsen, Jesper Ryg, Lene Juel Kjeldsen, Christian Backer Mogensen
Summary: Older patients using multiple medications daily face challenges such as non-adherence, confusion about medication information, and the need for medication reviews. Healthcare professionals need to prioritize communication about medication concerns.
Article
Geriatrics & Gerontology
Giulia Ogliari, Jesper Ryg, Karen Andersen-Ranberg, Lasse Lybecker Scheel-Hincke, Jemima T. Collins, Alison Cowley, Claudio Di Lorito, Vicky Booth, Roelof A. J. Smit, Ralph K. Akyea, Nadeem Qureshi, David A. Walsh, Rowan H. Harwood, Tahir Masud
Summary: This study investigates the longitudinal associations between pain and depressive symptoms in adults. The findings suggest that higher baseline pain intensity is associated with a greater risk of developing significant depressive symptoms in community-dwelling adults, at 2-year follow-up.
EUROPEAN GERIATRIC MEDICINE
(2023)
Article
Geriatrics & Gerontology
Nathalie J. van der Velde, Lotta J. Seppala, Sirpa Hartikainen, Nellie Kamkar, Louise Mallet, Tahir Masud, Manuel P. Montero-Odasso, Eveline P. van Poelgeest, Katja Thomsen, Jesper Ryg, Mirko Petrovic, EuGMS Task, Finish Grp Fall risk increasing drugs
Summary: Preventing and managing falls in older adults is a global challenge, and medication use is a key risk factor. The recent World Guidelines for Falls Prevention and Management recommend assessing fall history and risk before prescribing fall-risk-increasing drugs, using a screening tool for medication review, including deprescribing as part of falls prevention, and prioritizing deprescribing in long-term care. This paper outlines how to implement these recommendations in clinical practice and emphasizes the importance of personalized and patient-centered assessment.
EUROPEAN GERIATRIC MEDICINE
(2023)
Review
Geriatrics & Gerontology
Ditte Beck Jepsen, Emilie Sofie Bergen, Jeffrey Pan, Eveline van Poelgeest, Abdiaziz Osman, Alaa Burghle, Jesper Ryg, Wade Thompson, Carina Lundby
Summary: The lack of guidance on deprescribing is a major barrier for prescribers to consider deprescribing in daily practice. This study aims to evaluate the inclusion of bisphosphonate deprescribing recommendations in osteoporosis guidelines.
EUROPEAN GERIATRIC MEDICINE
(2023)
Article
Geriatrics & Gerontology
Eveline van Poelgeest, Lotta Seppala, Guelistan Bahat, Birkan Ilhan, Alpana Mair, Rob van Marum, Graziano Onder, Jesper Ryg, Marilia Andreia Fernandes, Antonio Cherubini, Michael Denkinger, Annette Eidam, Angelique Egberts, Aoalsteinn Gudmundsson, Fatma Ozge Kayhan Kocak, George Soulis, Jos Tournoy, Tahir Masud, Martin Wehling, Nathalie van der Velde
Summary: The current evidence supports the need for comprehensive and widespread changes in education, guidelines, research, advocacy, and policy to improve the management of polypharmacy in older adults. Recognizing this, the European Geriatric Medicine Society has formulated recommendations to enhance appropriate prescribing practices and make deprescribing part of routine care for older individuals.
EUROPEAN GERIATRIC MEDICINE
(2023)
Article
Geriatrics & Gerontology
Nathalie van der Velde, Lotta Seppala, Mirko Petrovic, Jesper Ryg, Maw Pin Tan, Manuel Montero-Odasso, Finbarr C. Martin, Tahir Masud
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)