标题
Germline CHEK2 and ATM Variants in Myeloid and Other Hematopoietic Malignancies
作者
关键词
-
出版物
Current Hematologic Malignancy Reports
Volume 17, Issue 4, Pages 94-104
出版商
Springer Science and Business Media LLC
发表日期
2022-06-08
DOI
10.1007/s11899-022-00663-7
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- ATM: Functions of ATM Kinase and Its Relevance to Hereditary Tumors
- (2022) Sayaka Ueno et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Feasibility and limitations of cultured skin fibroblasts for germline genetic testing in hematologic disorders
- (2022) Lia DeRoin et al. HUMAN MUTATION
- Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer
- (2021) Deepak Singhal et al. LEUKEMIA
- Germline risk of clonal haematopoiesis
- (2021) Alexander J. Silver et al. NATURE REVIEWS GENETICS
- Spectrum of hematological malignancies, clonal evolution and outcomes in 144 Mayo Clinic patients with germline predisposition syndromes
- (2021) Emma St Martin et al. AMERICAN JOURNAL OF HEMATOLOGY
- Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult AML patients
- (2021) Fei Yang et al. BLOOD
- Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis
- (2021) Ryunosuke Saiki et al. NATURE MEDICINE
- Re-evaluating cancer risks associated with the CHEK2 p.Ser428Phe Ashkenazi Jewish founder pathogenic variant
- (2021) Yael Laitman et al. Familial Cancer
- PARP Inhibitors and Myeloid Neoplasms: A Double-Edged Sword
- (2021) Clifford M. Csizmar et al. Cancers
- Abnormal expression of p-ATM/CHK2 in nasal extranodal NK/T cell lymphoma, nasal type, is correlated with poor prognosis
- (2020) Qiurong Ye et al. JOURNAL OF CLINICAL PATHOLOGY
- Role of DNA Damage Response in Suppressing Malignant Progression of Chronic Myeloid Leukemia and Polycythemia Vera: Impact of Different Oncogenes
- (2020) Jan Stetka et al. Cancers
- Germline variants discovered in lymphoma patients undergoing tumor profiling: a case series
- (2020) Anthony J. Scott et al. Familial Cancer
- Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
- (2020) Erik L. Bao et al. NATURE
- Inherited causes of clonal haematopoiesis in 97,691 whole genomes
- (2020) Alexander G. Bick et al. NATURE
- BRCA Mutations in Prostate Cancer: Prognostic and Predictive Implications
- (2020) Carlo Messina et al. Journal of Oncology
- Germline variants of DNA repair genes in early onset mantle cell lymphoma
- (2020) Xiaogan Wang et al. ONCOGENE
- CHEK2 Germline Variants in Cancer Predisposition: Stalemate Rather than Checkmate
- (2020) Lenka Stolarova et al. Cells
- Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasia
- (2020) Abrey J. Yeo et al. iScience
- ATM is activated by ATP depletion and modulates mitochondrial function through NRF1
- (2019) Hei-Man Chow et al. JOURNAL OF CELL BIOLOGY
- Effect of germline ATM mutations on clonal hematopoiesis.
- (2019) Thomas Paul Slavin et al. JOURNAL OF CLINICAL ONCOLOGY
- One in three highly selected Greek patients with breast cancer carries a loss-of-function variant in a cancer susceptibility gene
- (2019) Florentia Fostira et al. JOURNAL OF MEDICAL GENETICS
- Incidence of Germline ATM Variants in a Consecutive Clinical Cohort of CLL Patients
- (2019) Benjamin L. Lampson et al. BLOOD
- Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium
- (2019) Michael Goggins et al. GUT
- Germ line tissues for optimal detection of somatic variants in myelodysplastic syndromes
- (2018) Eric Padron et al. BLOOD
- Fanconi anaemia presenting as acute myeloid leukaemia and myelodysplastic syndrome in adulthood: a family report on co-occurring FANCC and CHEK2 mutations
- (2018) Gerbrig Berger et al. BRITISH JOURNAL OF HAEMATOLOGY
- Pathogenic Germline Variants in 10,389 Adult Cancers
- (2018) Kuan-lin Huang et al. CELL
- Histone deacetylase inhibitor chidamide induces growth inhibition and apoptosis in NK/T lymphoma cells through ATM-Chk2-p53-p21 signalling pathway
- (2018) Jianan Zhou et al. INVESTIGATIONAL NEW DRUGS
- Constitutional mutations of the CHEK2 gene are a risk factor for MDS, but not for de novo AML
- (2018) Hanna Janiszewska et al. LEUKEMIA RESEARCH
- Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL
- (2018) A. Schrader et al. Nature Communications
- Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma
- (2018) Maria I. Carlo et al. JAMA Oncology
- Colorectal cancer risk associated with the CHEK2 1100delC variant
- (2017) Bryson W. Katona et al. EUROPEAN JOURNAL OF CANCER
- Rare germline variants in ATM are associated with chronic lymphocytic leukemia
- (2017) G Tiao et al. LEUKEMIA
- Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN
- (2017) Nausica Arnoult et al. NATURE
- Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility
- (2017) Daniel J Wright et al. NATURE GENETICS
- Germline mutations predisposing to diffuse large B-cell lymphoma
- (2017) O C Leeksma et al. Blood Cancer Journal
- Significance of ATM Gene Polymorphisms in Chronic Myeloid Leukemia - a Case Control Study from India
- (2016) Manjula Gorre et al. Asian Pacific Journal of Cancer Prevention
- Mechanisms of non-canonical activation of ataxia telangiectasia mutated
- (2016) S. V. Khoronenkova BIOCHEMISTRY-MOSCOW
- Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms
- (2016) D. A. Hinds et al. BLOOD
- Aging of hematopoietic stem cells: DNA damage and mutations?
- (2016) Bettina M. Moehrle et al. EXPERIMENTAL HEMATOLOGY
- Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer
- (2016) Colin C. Pritchard et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ataxia telangiectasia: a review
- (2016) Cynthia Rothblum-Oviatt et al. Orphanet Journal of Rare Diseases
- ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia
- (2016) Mark A. Gregory et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PML nuclear body disruption impairs DNA double-strand break sensing and repair in APL
- (2016) A di Masi et al. Cell Death & Disease
- Breast cancer risk is similar for CHEK2 founder and non-founder mutation carriers
- (2016) Tracey P. Leedom et al. Cancer Genetics
- The ATM- and ATR-related SCD domain is over-represented in proteins involved in nervous system development
- (2016) Lukas Cara et al. Scientific Reports
- Mechanisms of ATM Activation
- (2015) Tanya T. Paull Annual Review of Biochemistry
- Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
- (2015) D. P. Steensma et al. BLOOD
- The germline mutations of theCHEK2gene are associated with an increased risk of polycythaemia vera
- (2015) Hanna Janiszewska et al. BRITISH JOURNAL OF HAEMATOLOGY
- Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia
- (2015) Jane E. Churpek et al. CANCER
- miR-181a promotes G1/S transition and cell proliferation in pediatric acute myeloid leukemia by targeting ATM
- (2015) Xiaodan Liu et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Incidence, Presentation, and Prognosis of Malignancies in Ataxia-Telangiectasia: A Report From the French National Registry of Primary Immune Deficiencies
- (2015) Felipe Suarez et al. JOURNAL OF CLINICAL ONCOLOGY
- DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer
- (2015) Joaquin Mateo et al. NEW ENGLAND JOURNAL OF MEDICINE
- ATM prevents DSB formation by coordinating SSB repair and cell cycle progression
- (2015) Svetlana V. Khoronenkova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Patterns and functional implications of rare germline variants across 12 cancer types
- (2015) Charles Lu et al. Nature Communications
- Replication Stress in Mammalian Cells and Its Consequences for Mitosis
- (2015) Camille Gelot et al. Genes
- Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma
- (2015) Ondrej Havranek et al. PLoS One
- Frequency of mutations in individuals with breast cancer referred forBRCA1andBRCA2testing using next-generation sequencing with a 25-gene panel
- (2014) Nadine Tung et al. CANCER
- Successful treatment of acute myeloid leukaemia in a patient with ataxia telangiectasia
- (2013) Tadashi Onoda et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Acute Lymphoblastic Leukemia in Early Childhood as the Presenting Sign of Ataxia-Telangiectasia Variant
- (2013) Bella Bielorai et al. PEDIATRIC HEMATOLOGY AND ONCOLOGY
- ATM polymorphism is associated with low risk myelodysplastic syndrome
- (2012) Howard Lopes Ribeiro et al. DNA REPAIR
- Lymphoid tumours and breast cancer in ataxia telangiectasia; substantial protective effect of residual ATM kinase activity against childhood tumours
- (2011) A Reiman et al. BRITISH JOURNAL OF CANCER
- Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia
- (2011) Sylvain Thépot et al. CELL CYCLE
- A risk of essential thrombocythemia in carriers of constitutional CHEK2 gene mutations
- (2011) H. Janiszewska et al. HAEMATOLOGICA
- Patient with ataxia telangiectasia who developed acute myeloid leukemia
- (2011) Annamaria Brioli et al. LEUKEMIA & LYMPHOMA
- Alterations of CHEK2 forkhead-associated domain increase the risk of Hodgkin lymphoma
- (2011) O. HAVRANEK et al. NEOPLASMA
- Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphoma
- (2011) Bojie Dai et al. Nature Communications
- Child With Ataxia Telangiectasia Developing Acute Myeloid Leukemia
- (2010) Chien-Heng Lin et al. JOURNAL OF CLINICAL ONCOLOGY
- Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome
- (2009) S Boehrer et al. ONCOGENE
- Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias
- (2009) E. M. Bahassi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Arsenic Trioxide Augments Chk2/p53-mediated Apoptosis by Inhibiting Oncogenic Wip1 Phosphatase
- (2008) Akinori Yoda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ATM mediates constitutive NF-κB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia
- (2008) J Grosjean-Raillard et al. ONCOGENE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now