Review
Psychiatry
Candice E. Crocker, Alix J. E. Carter, Jason G. Emsley, Kirk Magee, Paul Atkinson, Philip G. Tibbo
Summary: Cannabis use is associated with the development and exacerbation of mental illness, especially the risk of psychotic disorder. In emergency situations, cannabis-related adverse mental health events such as anxiety, suicidal thoughts, and psychotic symptoms are significant, particularly in youth and young adults. The differences in impact between alcohol and cannabis on emergency mental health services highlight the need for tailored interventions based on individual risk factors.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Chemistry, Medicinal
Maria Gallo, Estefania Moreno, Sira Defaus, Antonio Ortega-Alvaro, Angel Gonzalez, Patricia Robledo, Marco Cavaco, Vera Neves, Miguel A. R. B. Castanho, Vicent Casado, Leonardo Pardo, Rafael Maldonado, David Andreu
Summary: Optimizing peptides reproducing CB1R transmembrane helices 5 and 6 has led to the identification of an ideal candidate for cannabis-based pain management, preserving THC-induced analgesia while avoiding cognitive impairment.
JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Review
Otorhinolaryngology
Jobanjit S. Phulka, Joel W. Howlett, Amanda Hu
Summary: Cannabis use in otolaryngology is associated with unintended side effects such as tinnitus, vertigo, hearing loss, infection, malignancy, sinusitis, allergic rhinitis, thyroid dysfunction, and dyspnea. More than half of the studies showed increased side effects or no change in symptoms following cannabis use.
JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2021)
Review
Cardiac & Cardiovascular Systems
Marco Licciardi, Elena Utzeri, Maria Francesca Marchetti, Vincenzo Nissardi, Giovanni Cecchetto, Massimo Montisci, Roberta Montisci
Summary: Cannabis is one of the most commonly consumed drugs worldwide, with a growing number of users, especially among young people. Cannabis can potentially lead to cardiovascular diseases such as arrhythmias, myocardial infarction, and sudden death. Clinicians should pay attention to the relationship between cannabis use and cardiovascular complications.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Anesthesiology
Thomas J. Ebert, Craig E. Cumming, Christopher J. Roberts, Missy F. Anglin, Sweeta Gandhi, Christopher J. Anderson, Thomas A. Stekiel, Ross Gliniecki, Shannon M. Dugan, Mohamed T. Abdelrahim, Victoria B. Klinewski, Katherine Sherman
Summary: Reversal of neuromuscular blockade with sugammadex can cause changes in heart rate, but the relationship between dose and heart rate slowing remains unclear.
ANESTHESIA AND ANALGESIA
(2022)
Article
Multidisciplinary Sciences
Barrett Wallace Montgomery, Meaghan H. Roberts, Claire E. Margerison, James C. Anthony
Summary: This study evaluates the impact of state-level recreational cannabis policies in the US and finds an increase in newly onset cannabis use among older adults, but no significant changes among underage individuals. This research provides important insights into the effects of cannabis policies on different age groups.
Article
Psychology, Developmental
Amanda Stueber, Carrie Cuttler
Summary: The study found that individuals with ADHD are more likely to use cannabis, with frequent use potentially mitigating ADHD-related executive dysfunction. Participants reported acute beneficial effects of cannabis on ADHD symptoms and medication side effects.
JOURNAL OF ATTENTION DISORDERS
(2022)
Article
Public, Environmental & Occupational Health
Jennifer A. Bailey, Stacey S. Tiberio, David C. R. Kerr, Marina Epstein, Kimberly L. Henry, Deborah M. Capaldi
Summary: Canada, Uruguay, and 18 states in the U.S. have legalized nonmedical cannabis for adults, but the impact on adolescent cannabis use remains unclear. This study found that cannabis legalization did not predict changes in adolescent cannabis use among 13-18 year olds in Oregon, New York, and Washington. Findings suggest that legalization did not affect the prevalence or frequency of adolescent cannabis use.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2023)
Article
Psychology, Developmental
Hai Nguyen, Shweta Mital, Stephen Bornstein
Summary: This study examines the impacts of cannabis legalization on youth cannabis use in Canada. Findings show that the initiation rate among youths increased by 2.7 percentage points after legalization, but there was no significant increase in overall cannabis use prevalence. The average age of first cannabis use was also delayed by 4 months. The legalization led to heightened perception of cannabis harm and easier access to cannabis among youth.
JOURNAL OF ADOLESCENT HEALTH
(2023)
Review
Pediatrics
Judith Mercer, Debra Erickson-Owens, Heike Rabe, Ola Andersson
Summary: Births involving shoulder dystocia or tight nuchal cords can lead to rapid deterioration and asystole in newborns. This condition occurs when blood is redirected to the placenta, but prevented from returning to the infant due to cord compression. Immediate cord clamping (ICC) further restricts the newborn's access to this blood and can result in severe hypovolemia. Leaving the cord intact and performing umbilical cord milking allows for the return of this sequestered blood and may improve resuscitation outcomes. The placenta also plays a reparative role during the neonatal-placental circulation.
Article
Environmental Sciences
Hongzhang Xu, Aaron Tang, Jamie Pittock
Summary: China's recent commitments to the Paris Agreement have raised concerns about their feasibility. In order to achieve carbon neutrality, China has implemented extreme emission reduction measures, but the side-effects of its climate ambition have been overlooked. An intersectional and just transitions perspective is needed to examine limitations and trade-offs for broader societal goals.
ENVIRONMENTAL RESEARCH LETTERS
(2021)
Review
Psychiatry
Raffaele Nardone, Luca Sebastianelli, Viviana Versace, Davide Ferrazzoli, Francesco Brigo, Kerstin Schwenker, Leopold Saltuari, Eugen Trinka
Summary: The effects of cannabis on human cortical brain processes can be evaluated through transcranial magnetic stimulation (TMS). Persistent cannabis use is associated with reduced cortical inhibition, indicating neurobiological changes. Individuals vulnerable to long-term use may have pre-existing cortical inhibition abnormalities. Cannabis use is also linked to an increased risk of schizophrenia, possibly due to down-regulation of GABAergic function. Repetitive TMS applied to the dorsolateral prefrontal cortex (DLPFC) can result in less frequent cannabis use and craving. The posterior cingulate cortex and the precuneus show potential as targets for rTMS intervention in cannabis use disorder.
PSYCHIATRY RESEARCH
(2022)
Article
Anesthesiology
Joshua Aviram, Gil M. Lewitus, Yelena Vysotski, Paula Berman, Anna Shapira, Shiri Procaccia, David Meiri
Summary: Studies have shown that women are more susceptible to adverse effects from conventional drugs. This study aimed to investigate the differences of medical cannabis-related adverse effects between women and men in patients with chronic noncancer pain. The results showed that women reported more medical cannabis-related adverse effects, possibly due to both the inherent sex effect and the consumption of specific phytocannabinoid compositions.
Article
Oncology
Taylan Gurgenci, Gregor Kijanka, Ristan Greer, Georgie Huggett, Phillip Good, Md Moniruzzaman, Janet Hardy
Summary: This study aimed to investigate the anti-inflammatory effect of cannabidiol (CBD) in cancer patients by measuring the levels of serial C-reactive protein (CRP) and inflammatory cytokines. However, the results showed no significant difference in the trajectory of CRP or cytokine levels between the CBD and placebo groups.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Biochemistry & Molecular Biology
Morteza Abyadeh, Vivek Gupta, Joao A. Paulo, Veer Gupta, Nitin Chitranshi, Angela Godinez, Danit Saks, Mafruha Hasan, Ardeshir Amirkhani, Matthew McKay, Ghasem H. Salekdeh, Paul A. Haynes, Stuart L. Graham, Mehdi Mirzaei
Summary: This review discusses the therapeutic properties of cannabinoids found in cannabis for various diseases and the need for more research to understand the molecular and biochemical effects of cannabis at a cellular level. Proteomics technology is highlighted as an efficient tool to study the mechanistic effects of cannabis on the human body, drawing conclusions about its toxicity, therapeutic benefits, safety, and efficacy profiles.
Article
Medicine, General & Internal
Daniel Brancheau, Brijesh Patel, Marcel Zughaib
AMERICAN JOURNAL OF CASE REPORTS
(2015)
Article
Critical Care Medicine
DN Reed, A Saxe, M Montanez, R Kotlowski, DA Brancheau, C Coffey, M Pollard, H Fitzgerald, K Barber, B Wolf
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
(2005)
