The reversal of multidrug resistance in ovarian carcinoma cells by co-application of tariquidar and paclitaxel in transferrin-targeted polymeric micelles

Revisiting the role of nanoparticles as modulators of drug resistance and metabolism in cancer

(2016) Pranav Gupta et al.   Expert Opinion on Drug Metabolism & Toxicology

Pharmacokinetic strategies to improve drug penetration and entrapment within solid tumors

(2015) Ahmed M. Al-Abd et al.   JOURNAL OF CONTROLLED RELEASE

Whole–genome characterization of chemoresistant ovarian cancer

(2015) Ann-Marie Patch et al.   NATURE

The effect of co-delivery of paclitaxel and curcumin by transferrin-targeted PEG-PE-based mixed micelles on resistant ovarian cancer in 3-D spheroids and in vivo tumors

(2014) Can Sarisozen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Three Decades of P-gp Inhibitors: Skimming Through Several Generations and Scaffolds

(2012) A. Palmeira et al.   CURRENT MEDICINAL CHEMISTRY

PEG-PE-based micelles co-loaded with paclitaxel and cyclosporine A or loaded with paclitaxel and targeted by anticancer antibody overcome drug resistance in cancer cells

(2012) Can Sarisozen et al.   DRUG DELIVERY

Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG–PE micelles in ovarian cancer cell spheroid model

(2012) Federico Perche et al.   JOURNAL OF CONTROLLED RELEASE

Reversal of multidrug resistance by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes

(2011) Niravkumar R. Patel et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Transferrin Adsorption onto PLGA Nanoparticles Governs Their Interaction with Biological Systems from Blood Circulation to Brain Cancer Cells

(2011) Jiang Chang et al.   PHARMACEUTICAL RESEARCH

Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells

(2010) Daniela Loessner et al.   BIOMATERIALS

Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance

(2009) Yogesh Patil et al.   JOURNAL OF CONTROLLED RELEASE

Paclitaxel-loaded PLGA nanoparticles surface modified with transferrin and Pluronic®P85, anin vitrocell line andin vivobiodistribution studies on rat model

(2009) Neha Shah et al.   JOURNAL OF DRUG TARGETING

The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls

(2009) Dries Vercauteren et al.   MOLECULAR THERAPY

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype

(2008) Katharine L. Sodek et al.   INTERNATIONAL JOURNAL OF CANCER

Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors

(2007) K DOUGLAS   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS