期刊
JOURNAL OF DISPLAY TECHNOLOGY
卷 12, 期 3, 页码 -出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/JDT.2015.2479457
关键词
Biomarkers; flexible display; flexible electronics; fluorescent biorecognition; microarray; OLED; organic light emitting diodes (OLEDs); point-of-care; thin-film transistors (TFTs)
资金
- Army Research Laboratory (ARL) [W911NG-04-2-005]
- Div Of Information & Intelligent Systems
- Direct For Computer & Info Scie & Enginr [1521904] Funding Source: National Science Foundation
This paper presents a new concept combining flexible organic light-emitting diode (OLED) display technology with fluorescent biorecognition microarray technology to fabricate point-of-care immunobiosensors. Our approach is designed to leverage commercial OLED display technology to reduce pre-functionalized biosensor substrate costs to pennies per cm combined with leveraging the display industries ability to manufacture an immense number of low-cost consumer electronic products annually. For this work, we demonstrate that our new approach using high brightness flexible OLED display technology combined with a charge integrating readout circuit and optical filters can offer point-of-care diagnostic sensitivity at or below 10 pg/mL, which approaches the lower limit of detection (LLOD) of typical clinical laboratory instrumentation.
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