Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis

(2021) Jung-Hwan Kim et al.   Nature Communications

Lipid nanoparticles for mRNA delivery

(2021) Xucheng Hou et al.   Nature Reviews Materials

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

(2020) Yi-Hsien Cheng et al.   ACS Nano

Tuning Nanoparticle Interactions with Ovarian Cancer through Layer-by-Layer Modification of Surface Chemistry

(2020) Santiago Correa et al.   ACS Nano

How cancer genomics is transforming diagnosis and treatment

(2020) Bianca Nogrady   NATURE

Lipid nanoparticles for nucleic acid delivery: Current perspectives

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Electrostatic Conjugation of Nanoparticle Surfaces with Functional Peptide Motifs

(2020) Natalie Boehnke et al.   BIOCONJUGATE CHEMISTRY

A framework for designing delivery systems

(2020) Wilson Poon et al.   Nature Nanotechnology

MFSD12 mediates the import of cysteine into melanosomes and lysosomes

(2020) Charles H. Adelmann et al.   NATURE

A metastasis map of human cancer cell lines

(2020) Xin Jin et al.   NATURE

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

The Gene Ontology resource: enriching a GOld mine

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Elimination Pathways of Nanoparticles

(2019) Wilson Poon et al.   ACS Nano

Solution Conditions Tune and Optimize Loading of Therapeutic Polyelectrolytes into Layer-by-Layer Functionalized Liposomes

(2019) Santiago Correa et al.   ACS Nano

Next-generation characterization of the Cancer Cell Line Encyclopedia

(2019) Mahmoud Ghandi et al.   NATURE

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

(2019) Kimberly J. Hassett et al.   Molecular Therapy-Nucleic Acids

Increased expression of SLC46A3 to oppose the progression of hepatocellular carcinoma and its effect on sorafenib therapy

(2019) Qing Zhao et al.   BIOMEDICINE & PHARMACOTHERAPY

The origin of heterogeneous nanoparticle uptake by cells

(2019) Paul Rees et al.   Nature Communications

CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity

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Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing

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Perspectives on the past, present, and future of cancer nanomedicine

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Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells

(2018) Guangmin Li et al.   MOLECULAR CANCER THERAPEUTICS

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

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Reply to 'The interface of nanoparticles with proliferating mammalian cells'

(2017) Christoffer Åberg et al.   Nature Nanotechnology

The interface of nanoparticles with proliferating mammalian cells

(2017) Einat Panet et al.   Nature Nanotechnology

Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

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Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation

(2016) Oommen P. Oommen et al.   ACS Applied Materials & Interfaces

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Highly Scalable, Closed-Loop Synthesis of Drug-Loaded, Layer-by-Layer Nanoparticles

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High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines

(2016) Channing Yu et al.   NATURE BIOTECHNOLOGY

Antibody-drug conjugates: recent advances in conjugation and linker chemistries

(2016) Kyoji Tsuchikama et al.   Protein & Cell

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm

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Tumor-Targeted Synergistic Blockade of MAPK and PI3K from a Layer-by-Layer Nanoparticle

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Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs

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SLC transporters as therapeutic targets: emerging opportunities

(2015) Lawrence Lin et al.   NATURE REVIEWS DRUG DISCOVERY

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Bimodal Tumor-Targeting from Microenvironment Responsive Hyaluronan Layer-by-Layer (LbL) Nanoparticles

(2014) Erik C. Dreaden et al.   ACS Nano

Differential uptake of nanoparticles by endothelial cells through polyelectrolytes with affinity for caveolae

(2014) J. Voigt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity

(2014) Kathryn A. Whitehead et al.   Nature Communications

Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment

(2013) Zhou J. Deng et al.   ACS Nano

The architecture and biological performance of drug-loaded LbL nanoparticles

(2013) Stephen W. Morton et al.   BIOMATERIALS

An Extended Proteome Map of the Lysosomal Membrane Reveals Novel Potential Transporters

(2013) Agnès Chapel et al.   MOLECULAR & CELLULAR PROTEOMICS

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

(2012) Muthusamy Jayaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polysaccharide-Based Nanoparticles: A Versatile Platform for Drug Delivery and Biomedical Imaging

(2012) G. Saravanakumar et al.   CURRENT MEDICINAL CHEMISTRY

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

(2012) Eleonore Fröhlich   International Journal of Nanomedicine

Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

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(2011) A. Liberzon et al.   BIOINFORMATICS

Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population

(2011) Jong Ah Kim et al.   Nature Nanotechnology