Silibinin Ameliorates Formaldehyde-Induced Cognitive Impairment by Inhibiting Oxidative Stress

Box-Behnken design optimized silibinin loaded glycerylmonooleate nanoliquid crystal for brain targeting

(2022) Ajit Singh et al.   CHEMISTRY AND PHYSICS OF LIPIDS

DHCR24 Knock-Down Induced Tau Hyperphosphorylation at Thr181, Ser199, Thr231, Ser262, Ser396 Epitopes and Inhibition of Autophagy by Overactivation of GSK3β/mTOR Signaling

(2021) Xiaojing Bai et al.   Frontiers in Aging Neuroscience

Silibinin-Albumin Nanoparticles: Characterization and Biological Evaluation Against Oxidative Stress-Stimulated Neurotoxicity Associated with Alzheimer’s Disease

(2021) Qichen Pan et al.   Journal of Biomedical Nanotechnology

Biomimetic silibinin-loaded macrophage-derived exosomes induce dual inhibition of Aβ aggregation and astrocyte activation to alleviate cognitive impairment in a model of Alzheimer's disease

(2021) Qinghao Huo et al.   Materials Science & Engineering C-Materials for Biological Applications

Tackling of Renal Carcinogenesis in Wistar Rats by Silybum marianum Total Extract, Silymarin, and Silibinin via Modulation of Oxidative Stress, Apoptosis, Nrf2, PPARγ, NF-κB, and PI3K/Akt Signaling Pathways

(2021) Nour Y. S. Yassin et al.   Oxidative Medicine and Cellular Longevity

Vitamin D Protects Against Alcohol-Induced Liver Cell Injury Within an NRF2-ALDH2 Feedback Loop

(2019) Hong Zhang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Natural silibinin modulates amyloid precursor protein processing and amyloid-β protein clearance in APP/PS1 mice

(2019) Dafeng Bai et al.   Journal of Physiological Sciences

Xanthoceraside attenuates amyloid β peptide 1-42 -induced memory impairments by reducing neuroinflammatory responses in mice

(2018) Yue Qi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

13 reasons why the brain is susceptible to oxidative stress

(2018) James Nathan Cobley et al.   Redox Biology

Milk thistle (Silybum marianum ): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases

(2018) Ludovico Abenavoli et al.   PHYTOTHERAPY RESEARCH

Aldehyde toxicity and metabolism: The role of aldehyde dehydrogenases in detoxification, drug resistance and carcinogenesis

(2018) Amaj Ahmed Laskar et al.   DRUG METABOLISM REVIEWS

ALDH2 attenuates early-stage STZ-induced aged diabetic rats retinas damage via Sirt1/Nrf2 pathway

(2018) Mengshan He et al.   LIFE SCIENCES

Antioxidative and Anti-Apoptotic Roles of Silibinin in Reversing Learning and Memory Deficits in APP/PS1 Mice

(2017) Dafeng Bai et al.   NEUROCHEMICAL RESEARCH

Nrf2, cellular redox regulation, and neurologic implications

(2017) Eduardo E. Benarroch   NEUROLOGY

Increased Total TAU But Not Amyloid-β42; in Cerebrospinal Fluid Correlates with Short-Term Memory Impairment in Alzheimer's Disease

(2017) Yuh-Te Lin et al.   JOURNAL OF ALZHEIMERS DISEASE

Chromogenic Detection of Aqueous Formaldehyde Using Functionalized Silica Nanoparticles

(2016) Sameh El Sayed et al.   ACS Applied Materials & Interfaces

Activation of apoptosis signalling pathways by reactive oxygen species

(2016) Maureen Redza-Dutordoir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Determination of formaldehyde in food and feed by an in-house validated HPLC method

(2016) P. Wahed et al.   FOOD CHEMISTRY

The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic

(2015) Maria A. O’Connell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Brain Glutathione Levels – A Novel Biomarker for Mild Cognitive Impairment and Alzheimer’s Disease

(2015) Pravat K. Mandal et al.   BIOLOGICAL PSYCHIATRY

Icariin protects SH-SY5Y cells from formaldehyde-induced injury through suppression of Tau phosphorylation

(2015) Yi-xiang Song et al.   Chinese Journal of Integrative Medicine

Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis

(2015) Maki Goto et al.   GENES TO CELLS

Silibinin inhibits acetylcholinesterase activity and amyloid β peptide aggregation: a dual-target drug for the treatment of Alzheimer’s disease

(2015) Songwei Duan et al.   NEUROBIOLOGY OF AGING

Free radicals, reactive oxygen species, oxidative stress and its classification

(2014) Volodymyr I. Lushchak   CHEMICO-BIOLOGICAL INTERACTIONS

Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo

(2013) Jing Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Oxaliplatin-Induced Neuropathy: Oxidative Stress as Pathological Mechanism. Protective Effect of Silibinin

(2012) Lorenzo Di Cesare Mannelli et al.   JOURNAL OF PAIN

Formaldehyde-mediated Hyperphosphorylation Disturbs The Interaction Between Tau Protein and DNA*

(2012) Jing LU et al.   PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS

Tau phosphorylation in hippocampus results in toxic gain-of-function

(2010) Jesús Avila et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Formaldehyde stress

(2010) RongQiao He et al.   Science China-Life Sciences

Silibinin prevents amyloid β peptide-induced memory impairment and oxidative stress in mice

(2009) P Lu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Formaldehyde in China: Production, consumption, exposure levels, and health effects

(2009) Xiaojiang Tang et al.   ENVIRONMENT INTERNATIONAL

Silymarin Ascending Multiple Oral Dosing Phase I Study in Noncirrhotic Patients With Chronic Hepatitis C

(2009) Roy L. Hawke et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Widespread Changes in Dendritic Spines in a Model of Alzheimer's Disease

(2008) S. Knafo et al.   CEREBRAL CORTEX

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

(2008) Konstanze F Winklhofer et al.   EMBO JOURNAL

The association of mitochondrial aldehyde dehydrogenase gene (ALDH2) polymorphism with susceptibility to late-onset Alzheimer's disease in Chinese

(2008) Binbin Wang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES