Review
Infectious Diseases
Kasem Kulkeaw
Summary: Drug-resistant Plasmodium poses a frequent global threat in malaria eradication programs; the use of nucleic acid-binding fluorescent dyes and flow cytometry for parasite counting and discrimination faces challenges; evaluating the utility of fluorochromes in drug susceptibility tests is crucial for improving drug discovery and supporting resistance surveillance systems.
Article
Materials Science, Multidisciplinary
Xuan Zhang, Huazhang Guo, Changhan Chen, Biao Quan, Zhiming Zeng, Jing Xu, Zeyu Chen, Liang Wang
Summary: Photoacoustic-fluorescence imaging is a promising medical imaging technology that offers real-time, fast, and highly sensitive imaging capabilities for specialties such as ophthalmology, otorhinolaryngology, and dermatology. A series of nitrogen-doped carbon quantum dots (N-CQDs) with narrow size distribution and tunable optical capability were synthesized through a molecular fusion strategy. The N-CQDs demonstrated fast imaging velocity, rapid metabolism, and enhanced permeability and retention effect, enabling better accumulation in the tumor region. The molecular fusion strategy provides a guideline to design advanced N-CQDs for comprehensive and accurate tumor imaging.
APPLIED MATERIALS TODAY
(2023)
Article
Materials Science, Multidisciplinary
Anumol Mathew, Arun Varghese, K. R. Sunaja Devi, Dephan Pinheiro
Summary: Carbon dots have gained significant attention in the biomedical realm due to their exceptional characteristics. The introduction of heteroatoms via doping further enhances their unique attributes. Researchers have developed various techniques for doping carbon dots with metallic and non-metallic elements. This review compiles the methodologies and elements employed in recent times and discusses the biomedical applications of doped carbon dots.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Jiahao Huang, Chen Dong, Jiahui Xu, Jun Xuan, Qin Cheng, Hong Bi
Summary: N,Cl-CDs carbon dots have the potential to be used in plant lighting due to their blue-white emission, and their blue and red emission ranges meet the optimal requirement of plant lighting without the need for other luminescent materials.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Environmental Sciences
Sathishkumar Munusamy, Triveni Rajashekhar Mandlimath, Puchakayala Swetha, Abdullah G. Al-Sehemi, Mehboobali Pannipara, Sivasankar Koppala, Paramasivam Shanmugam, Supakorn Boonyuen, Ramyakrishna Pothu, Rajender Boddula
Summary: Doped carbon dots with nitrogen have attracted great attention due to their unique characteristics and have been widely explored in various applications. This article reviews the recent breakthroughs in nitrogen-doped carbon dots for fluorescent sensor applications, including synthetic methods, fluorescent features, sensing mechanisms, and sensor applications for various targets. The potential future directions of nitrogen-doped carbon dots in primary research are also discussed.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Xiaoman Huang, Junjie Lin, Jiarong Liang, Erfeng Kou, Wenxiao Cai, Yinjian Zheng, Haoran Zhang, Xuejie Zhang, Yingliang Liu, Wei Li, Bingfu Lei
Summary: Carbon dots doped with pyridinic nitrogen (Lev-CDs) were synthesized by the one-pot hydrothermal method, and the structure-function relationship between functional groups on Lev-CDs and photosynthesis of Chlorella pyrenoidosa was proposed. Pyridinic nitrogen plays a key role in the positive effect on photosynthesis caused by Lev-CDs. Lev-CDs act as electron donors and supply photo-induced electrons to the photosynthetic electron transport chain, enhancing the electron transfer rate, the activity of photosystem II, and the Calvin cycle.
Article
Spectroscopy
Guo-Qi Zhang, Xu-Yan Zhang, Ya-Xiong Luo, Yong-Sheng Li, Yang Zhao, Xiu-Feng Gao
Summary: A novel ultrasensitive and rapid turn-on fluorescence sensor was developed for the determination of metformin hydrochloride (MET) in biological fluids. The sensor effectively reduces the consumption of expensive reagents and shows a linear correlation under optimal conditions with a low detection limit.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Physical
Chenyang Shu, Chaozhong Guo, Xinru Xu, Lingtao Sun, Yao Liu, Hongdian Chen, Chuanlan Xu, Rong Jin, Yujun Si, Haifeng Chen
Summary: This study presents a new strategy for synthesizing nitrogen-doped carbon sheets and carbon quantum dots with large specific surface area and micro-porosity. The synthesized material exhibits comparable activity and superior stability to the precious metal catalyst Pt/C in the carbon-based oxygen reduction reaction. In zinc-air batteries, the material delivers higher peak power density and gravimetric energy density, as well as outstanding catalytic durability.
APPLIED SURFACE SCIENCE
(2024)
Article
Biochemistry & Molecular Biology
Pingping Liu, Lu Ga, Yong Wang, Jun Ai
Summary: Water-soluble nitrogen-doped carbon dots (N-CDs) with excellent optical and fluorescence thermal properties were prepared by the hydrothermal method using 4-dimethylaminopyridine and N,N'-methylenebisacrylamide as precursors. Co2+ selectively burst the fluorescence of N-CDs, showing high sensitivity and detection limit. In addition, the N-CDs' temperature response and optical properties make them potential candidates in the field of fluorescent inks and temperature sensing.
Article
Chemistry, Multidisciplinary
Cheng Ma, Min-Xuan Wang, Hui-Fang Wei, Shaojun Wu, Jian-Rong Zhang, Jun-Jie Zhu, Zixuan Chen
Summary: Catalytic route electrochemiluminescence (ECL) microscopy allows imaging of upper cell membranes, providing vertical resolution for studying ECL profiles at different heights and enabling imaging of externalized phosphatidylserine.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Fengzhou Xu, Huaying Tang, Jianhua Yu, Jia Ge
Summary: A Cu2+-assisted fluorescence switch biosensor utilizing nitrogen-doped carbon dots (N-CDs) was developed for the detection of coenzyme A (CoA), showing a sensitive and selective detection with a good linear relationship and a low detection limit. The sensor could successfully detect CoA in human serum samples, demonstrating great potential for CoA-dependent bioresearch applications.
Article
Chemistry, Multidisciplinary
Wenli Li, Ju Tang, Yuzhao Li, Han Bai, Weizuo Zhang, Jin Zhang, Yiming Xiao, Wen Xu
Summary: This study synthesized multi-color fluorescent materials with nitrogen-doped CNDs using a fast and effective microwave method, and investigated the influence of different raw material ratios on the structure and optical properties of N-CNDs. Results showed that the PL emission wavelength of N-CNDs can be tuned by controlling the N concentration, and the PL intensity is positively correlated with the content of C-O groups on the surface/edges of N-CNDs.
Article
Chemistry, Physical
Tzu-Yang Cheng, Feng-Pai Chou, Sheng-Cih Huang, Chin-Yuan Chang, Tung-Kung Wu
Summary: This article describes the synthesis of stable S,N co-doped graphene oxide quantum dots (S,N-GOQDs) and their optoelectrical applications. The S,N-GOQDs exhibit high yield and excitation-independent emission, making them suitable for use as emitters in light-emitting diode devices and as photocatalysts for energy conversion.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Chemistry, Analytical
Aikun Liu, Haojie Cai, Yutian Zeng, Yu Chen, Xiantong Yu, Jun Song, Pengju Zeng, Junle Qu, Jiaqing Guo, Hao Li
Summary: In this study, nitrogen-doped carbon dots were synthesized using a one-step hydrothermal method, and it was demonstrated that they can serve as a fluorescence indicator for monitoring HS-. Moreover, the carbon dots can also be used as a probe for fluorescence imaging in living cells.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Hari Krishna Sadhanala, Saurav Aryal, Kusha Sharma, Ziv Orpaz, Shulamit Michaeli, Aharon Gedanken
Summary: In this study, photoluminescent N-doped carbon dots were synthesized and used for the selective detection and imaging of intracellular magnesium ions. This is the first report of using carbon dots for sensing and imaging of magnesium ions in cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
