Kidney omics in hypertension: from statistical associations to biological mechanisms and clinical applications
出版年份 2022 全文链接
标题
Kidney omics in hypertension: from statistical associations to biological mechanisms and clinical applications
作者
关键词
-
出版物
KIDNEY INTERNATIONAL
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2022-06-10
DOI
10.1016/j.kint.2022.04.045
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Linking Genetics and Proteomics: Gene-Protein Associations Built on Diversity
- (2022) Heribert Schunkert et al. CIRCULATION
- A genome-wide association study of serum proteins reveals shared loci with common diseases
- (2022) Alexander Gudjonsson et al. Nature Communications
- Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney
- (2021) Amin Abedini et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- A call to action for new global approaches to cardiovascular disease drug solutions
- (2021) Gemma A Figtree et al. EUROPEAN HEART JOURNAL
- Advances in Genomics Research of Blood Pressure Responses to Dietary Sodium and Potassium Intakes
- (2021) Michael A. Razavi et al. HYPERTENSION
- Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney
- (2021) James M. Eales et al. NATURE GENETICS
- Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci
- (2021) Charles E. Breeze et al. Genome Medicine
- Causal associations of obesity with chronic kidney disease and arterial stiffness: a Mendelian randomization study
- (2021) Chaojie Ye et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study
- (2021) Pamela R. Matías-García et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
- (2021) Xin Sheng et al. NATURE GENETICS
- Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension
- (2021) Bin Zhou et al. Nature Reviews Cardiology
- Nitric oxide signalling in kidney regulation and cardiometabolic health
- (2021) Mattias Carlström Nature Reviews Nephrology
- Gaining insight into metabolic diseases from human genetic discoveries
- (2021) Melina Claussnitzer et al. TRENDS IN GENETICS
- Contributions of obesity to kidney health and disease: insights from Mendelian randomization and the human kidney transcriptomics
- (2021) Xiaoguang Xu et al. CARDIOVASCULAR RESEARCH
- Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease
- (2021) Jie Zheng et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Exome sequencing and analysis of 454,787 UK Biobank participants
- (2021) Joshua D. Backman et al. NATURE
- Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification
- (2021) Yi Ding et al. NATURE GENETICS
- Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps
- (2021) et al. NATURE MEDICINE
- The assembly, regulation and function of the mitochondrial respiratory chain
- (2021) Irene Vercellino et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Kynurenine pathway in kidney diseases
- (2021) Izabela Zakrocka et al. Pharmacological Reports
- T-cell senescence accelerates Angiotensin II-induced target organ damage
- (2020) Xiao-Xi Pan et al. CARDIOVASCULAR RESEARCH
- A Guide to the Short, Long and Circular RNAs in Hypertension and Cardiovascular Disease
- (2020) Priscilla R. Prestes et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure.
- (2020) Zhi Yu et al. KIDNEY INTERNATIONAL
- Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure
- (2020) Yisong Huang et al. HYPERTENSION
- Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis
- (2020) Tom van der Wel et al. Nature Communications
- Role of Interleukin-23/Interleukin-17 Axis in T-Cell Mediated Actions in Hypertension
- (2020) Akinori Higaki et al. CARDIOVASCULAR RESEARCH
- Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- (2020) Christopher J L Murray et al. LANCET
- Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
- (2020) Praveen Surendran et al. NATURE GENETICS
- Mitochondrial quality control in kidney injury and repair
- (2020) Chengyuan Tang et al. Nature Reviews Nephrology
- Crosstalk between mitochondrial hyperacetylation and oxidative stress in vascular dysfunction and hypertension
- (2019) Sergey I Dikalov et al. ANTIOXIDANTS & REDOX SIGNALING
- Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics
- (2019) Joshua Rowland et al. KIDNEY INTERNATIONAL
- The secret messages between mitochondria and nucleus in muscle cell biology
- (2019) Roman Barbara Soledad et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Genetic analyses of diverse populations improves discovery for complex traits
- (2019) Genevieve L. Wojcik et al. NATURE
- Overview of Monogenic or Mendelian Forms of Hypertension
- (2019) Rupesh Raina et al. Frontiers in Pediatrics
- Heritability of blood pressure traits in diverse populations: a systematic review and meta-analysis
- (2019) Goodarz Kolifarhood et al. JOURNAL OF HUMAN HYPERTENSION
- A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
- (2018) Yun J. Sung et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases
- (2018) Masahiro Kanai et al. NATURE GENETICS
- Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate
- (2018) Ryan B Gil et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Assembling the mitochondrial ATP synthase
- (2018) Jiyao Song et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
- (2018) Christopher R. Martens et al. Nature Communications
- Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci
- (2018) Boxiang Liu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome
- (2018) Christopher E. Gillies et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Enhancing Mitochondrial Health to Treat Hypertension
- (2018) Alfonso Eirin et al. CURRENT HYPERTENSION REPORTS
- Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
- (2018) Evangelos Evangelou et al. NATURE GENETICS
- Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease
- (2018) Chengxiang Qiu et al. NATURE MEDICINE
- De novo NAD+ synthesis enhances mitochondrial function and improves health
- (2018) Elena Katsyuba et al. NATURE
- Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
- (2018) Ayush Giri et al. NATURE GENETICS
- Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies
- (2018) Andrew P. Morris et al. Nature Communications
- Molecular insights into genome-wide association studies of chronic kidney disease-defining traits
- (2018) Xiaoguang Xu et al. Nature Communications
- Therapeutic Targeting of IRFs: Pathway-Dependence or Structure-Based?
- (2018) Cherrie D. Thompson et al. Frontiers in Immunology
- Moving Beyond Office Blood Pressure to Achieve a Personalized and More Precise Hypertension Management
- (2017) Gianfranco Parati et al. HYPERTENSION
- Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the KidneyNovelty and Significance
- (2017) Louise V. Wain et al. HYPERTENSION
- Nicotinamide nucleotide transhydrogenase activity impacts mitochondrial redox balance and the development of hypertension in mice
- (2017) Igor Leskov et al. Journal of the American Society of Hypertension
- Physiology and Pathophysiology of the Intrarenal Renin-Angiotensin System: An Update
- (2017) Tianxin Yang et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
- (2017) Helen R Warren et al. NATURE GENETICS
- NAD Deficiency, Congenital Malformations, and Niacin Supplementation
- (2017) Hongjun Shi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations
- (2017) Jingjing Liang et al. PLoS Genetics
- Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling
- (2017) Connor A. Emdin et al. CIRCULATION
- Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation
- (2016) Catherine Do et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Circulating microRNAs and hypertension—from new insights into blood pressure regulation to biomarkers of cardiovascular risk
- (2016) Simon PR Romaine et al. CURRENT OPINION IN PHARMACOLOGY
- Mendelian Randomization as an Approach to Assess Causality Using Observational Data
- (2016) P. Sekula et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci
- (2016) Chunyu Liu et al. NATURE GENETICS
- Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
- (2016) Praveen Surendran et al. NATURE GENETICS
- Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation
- (2016) Thomas J Hoffmann et al. NATURE GENETICS
- Transcription factors as readers and effectors of DNA methylation
- (2016) Heng Zhu et al. NATURE REVIEWS GENETICS
- Long noncoding RNAs in kidney and cardiovascular diseases
- (2016) Johan M. Lorenzen et al. Nature Reviews Nephrology
- MicroRNAs in cardiovascular disease: an introduction for clinicians
- (2015) Simon P R Romaine et al. HEART
- Renal Mechanisms of Association between Fibroblast Growth Factor 1 and Blood Pressure
- (2015) M. Tomaszewski et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Unknown
- (2015) Francine Marques et al. MOLECULAR MEDICINE
- Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
- (2015) Norihiro Kato et al. NATURE GENETICS
- Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers
- (2015) Sarah Voisin et al. Genome Medicine
- A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins
- (2015) Katja Gotthardt et al. eLife
- Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type
- (2014) Alicia K Smith et al. BMC GENOMICS
- The emerging role of non-coding RNA in essential hypertension and blood pressure regulation
- (2014) F Z Marques et al. JOURNAL OF HUMAN HYPERTENSION
- Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations
- (2013) Nora Franceschini et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Interferon-γ biphasically regulates angiotensinogen expression via a JAK-STAT pathway and suppressor of cytokine signaling 1 (SOCS1) in renal proximal tubular cells
- (2012) Ryousuke Satou et al. FASEB JOURNAL
- Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants
- (2012) E R Gamazon et al. MOLECULAR PSYCHIATRY
- The Epithelial Sodium Channel γ-Subunit Gene and Blood Pressure
- (2011) Cara J. Büsst et al. HYPERTENSION
- mSIN1 Protein Mediates SGK1 Protein Interaction with mTORC2 Protein Complex and Is Required for Selective Activation of the Epithelial Sodium Channel
- (2011) Ming Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pathway Analysis Shows Association between FGFBP1 and Hypertension
- (2011) M. Tomaszewski et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
- (2011) Georg B. Ehret et al. NATURE
- Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
- (2011) Louise V Wain et al. NATURE GENETICS
- Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians
- (2011) Norihiro Kato et al. NATURE GENETICS
- Processing of Pro-B-Type Natriuretic Peptide: Furin and Corin as Candidate Convertases
- (2010) A. G. Semenov et al. CLINICAL CHEMISTRY
- Genetic Architecture of Ambulatory Blood Pressure in the General Population
- (2010) Maciej Tomaszewski et al. HYPERTENSION
- IRAK1BP1 inhibits inflammation by promoting nuclear translocation of NF- B p50
- (2010) J. R. Conner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
- (2009) Yoon Shin Cho et al. NATURE GENETICS
- Genome-wide association study of blood pressure and hypertension
- (2009) Daniel Levy et al. NATURE GENETICS
- Common Variants in Genes Underlying Monogenic Hypertension and Hypotension and Blood Pressure in the General Population
- (2008) Martin D. Tobin et al. HYPERTENSION
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search