Uremic mouse model to study vascular calcification and “inflamm-aging”

Medial Arterial Calcification

(2021) Peter Lanzer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Vascular Calcification in Rodent Models—Keeping Track with an Extented Method Assortment

(2021) Jaqueline Herrmann et al.   Biology-Basel

Stressor-Induced “Inflammaging” of Vascular Smooth Muscle Cells via Nlrp3-Mediated Pro-inflammatory Auto-Loop

(2021) Jaqueline Herrmann et al.   Frontiers in Cardiovascular Medicine

Research Models for Studying Vascular Calcification

(2020) Jaqueline Herrmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lack of Endothelial Nitric Oxide Synthase Accelerates Ectopic Calcification in Uremic Mice Fed an Adenine and High Phosphorus Diet

(2020) Yuji Oe et al.   AMERICAN JOURNAL OF PATHOLOGY

Peroxisome proliferator-activated receptor-γ coactivator-1α inhibits vascular calcification through sirtuin 3‒mediated reduction of mitochondrial oxidative stress

(2019) Han Feng et al.   ANTIOXIDANTS & REDOX SIGNALING

Arterial “inflammaging” drives vascular calcification in children on dialysis

(2019) Pilar Sanchis et al.   KIDNEY INTERNATIONAL

Inhibition of tissue‐nonspecific alkaline phosphatase protects against medial arterial calcification and improved survival probability in the CKD‐MBD mouse model

(2019) Takashi Tani et al.   JOURNAL OF PATHOLOGY

Targeting proinflammatory cytokines ameliorates calcifying phenotype conversion of vascular progenitors under uremic conditions in vitro

(2018) Björn Hegner et al.   Scientific Reports

Development of a novel chronic kidney disease mouse model to evaluate the progression of hyperphosphatemia and associated mineral bone disease

(2017) Takashi Tani et al.   Scientific Reports

Smooth Muscle–Selective Nuclear Factor‐κB Inhibition Reduces Phosphate‐Induced Arterial Medial Calcification in Mice With Chronic Kidney Disease

(2017) Tadashi Yoshida et al.   Journal of the American Heart Association

From C-Reactive Protein to Interleukin-6 to Interleukin-1

(2016) Paul M Ridker   CIRCULATION RESEARCH

Arteriosclerosis and vascular calcification: causes, clinical assessment and therapy

(2015) Markus Tölle et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Vascular calcification: Mechanisms of vascular smooth muscle cell calcification

(2015) Jane A. Leopold   TRENDS IN CARDIOVASCULAR MEDICINE

Harmful Effects of the Azathioprine Metabolite 6-Mercaptopurine in Vascular Cells: Induction of Mineralization

(2014) Jasmin Prüfer et al.   PLoS One

Nalp3 inflammasome is activated and required for vascular smooth muscle cell calcification

(2013) Chaoyang Wen et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Effect of a magnesium-based phosphate binder on medial calcification in a rat model of uremia

(2013) Tineke M. De Schutter et al.   KIDNEY INTERNATIONAL

Early chronic kidney disease–mineral bone disorder stimulates vascular calcification

(2013) Yifu Fang et al.   KIDNEY INTERNATIONAL

Thalidomide suppresses inflammation in adenine-induced CKD with uraemia in mice

(2013) Alexandre C. Santana et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

High-density lipoprotein loses its anti-inflammatory capacity by accumulation of pro-inflammatory-serum amyloid A

(2012) Markus Tölle et al.   CARDIOVASCULAR RESEARCH

Cardiovascular disease in an adenine-induced model of chronic kidney disease

(2012) Navid Shobeiri et al.   JOURNAL OF HYPERTENSION

DNA damage checkpoints in stem cells, ageing and cancer

(2012) Tobias Sperka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High phosphate feeding promotes mineral and bone abnormalities in mice with chronic kidney disease

(2012) Wei Ling Lau et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Elastin Degradation and Vascular Smooth Muscle Cell Phenotype Change Precede Cell Loss and Arterial Medial Calcification in a Uremic Mouse Model of Chronic Kidney Disease

(2011) Ashwini Pai et al.   AMERICAN JOURNAL OF PATHOLOGY

Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification

(2011) Mirjam Schuchardt et al.   KIDNEY INTERNATIONAL

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition

(2009) Ritsuko Nakano-Kurimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Microarray analysis of senescent vascular smooth muscle cells: A link to atherosclerosis and vascular calcification

(2009) Dominick G.A. Burton et al.   EXPERIMENTAL GERONTOLOGY

Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin

(2009) Mohga M. El-Abbadi et al.   KIDNEY INTERNATIONAL

Plasma interleukin-6 is independently associated with mortality in both hemodialysis and pre-dialysis patients with chronic kidney disease

(2009) Daniela V. Barreto et al.   KIDNEY INTERNATIONAL

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Cell surface-bound IL-1  is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

(2009) A. V. Orjalo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum Amyloid-A Rather Than C-Reactive Protein Is a Better Predictor of Mortality in Hemodialysis Patients

(2009) Sanja Simic-Ogrizovic et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Age-Related Reference Intervals of the Main Biochemical and Hematological Parameters in C57BL/6J, 129SV/EV and C3H/HeJ Mouse Strains

(2008) Cristina Mazzaccara et al.   PLoS One