Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics

标题
Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics
作者
关键词
Cysteine-engineered antibodies, Site-specific conjugation, Antibody-drug conjugates, In vivo efficacy, Tubulysin, Fc-gamma receptors
出版物
JOURNAL OF CONTROLLED RELEASE
Volume 236, Issue -, Pages 100-116
出版商
Elsevier BV
发表日期
2016-06-21
DOI
10.1016/j.jconrel.2016.06.025

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