标题
POLE/POLD1 mutation and tumor immunotherapy
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 41, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-07-02
DOI
10.1186/s13046-022-02422-1
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Non-Exonuclease Domain POLE Mutations Associated with Immunotherapy Benefit
- (2022) Sharlene Dong et al. ONCOLOGIST
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Assessment of POLE and POLD1 mutations as prognosis and immunotherapy biomarkers for stomach adenocarcinoma
- (2021) Mingyu Zhu et al. Translational Cancer Research
- Distinct mutational profile and immune microenvironment in microsatellite-unstable and POLE-mutated tumors
- (2021) Hee Sang Hwang et al. Journal for ImmunoTherapy of Cancer
- Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Neuroendocrine Tumors: Results From the Phase 2 KEYNOTE-158 Study
- (2020) Jonathan R Strosberg et al. CLINICAL CANCER RESEARCH
- Pedigree analysis of a POLD1 germline mutation in urothelial carcinoma shows a close association between different mutation burdens and overall survival
- (2020) Yejinpeng Wang et al. Cellular & Molecular Immunology
- Tumour mutational burden as a biomarker for immunotherapy: Current data and emerging concepts
- (2020) Jean-David Fumet et al. EUROPEAN JOURNAL OF CANCER
- High polymerase ε expression associated with increased CD8+T cells improves survival in patients with non-small cell lung cancer
- (2020) Kyueng-Whan Min et al. PLoS One
- POLE2 knockdown reduce tumorigenesis in esophageal squamous cells
- (2020) Yongjun Zhu et al. Cancer Cell International
- Somatic POLE exonuclease domain mutations elicit enhanced intratumoral immune responses in stage II colorectal cancer
- (2020) Shaobo Mo et al. Journal for ImmunoTherapy of Cancer
- DNA polymerase and mismatch repair exert distinct microsatellite instability signatures in normal and malignant human cells
- (2020) Jiil Chung et al. Cancer Discovery
- Genomic Comparison of Endometrioid Endometrial Carcinoma and Its Precancerous Lesions in Chinese Patients by High-Depth Next Generation Sequencing
- (2019) Yao Wang et al. Frontiers in Oncology
- FDA Approval Summary: Pembrolizumab for the treatment of microsatellite instability-high solid tumors
- (2019) Leigh Marcus et al. CLINICAL CANCER RESEARCH
- Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities
- (2019) Suhas Vasaikar et al. CELL
- Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study
- (2019) Hyun Cheol Chung et al. JOURNAL OF CLINICAL ONCOLOGY
- Evaluation of POLE and POLD1 Mutations as Biomarkers for Immunotherapy Outcomes Across Multiple Cancer Types
- (2019) Feng Wang et al. JAMA Oncology
- Classification of Endometrial Carcinoma
- (2019) Mohammed Akhtar et al. ADVANCES IN ANATOMIC PATHOLOGY
- Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population
- (2019) Jianfei Yao et al. Scientific Reports
- Alteration in TET1 as potential biomarker for immune checkpoint blockade in multiple cancers
- (2019) Hao-Xiang Wu et al. Journal for ImmunoTherapy of Cancer
- Interpretation of somatic POLE mutations in endometrial carcinoma
- (2019) Alicia León‐Castillo et al. JOURNAL OF PATHOLOGY
- Exceptional Response of Cryoablation Followed by Pembrolizumab in a Patient with Metastatic Cervical Carcinosarcoma with High Tumor Mutational Burden: A Case Report
- (2019) Baorang Zhu et al. ONCOLOGIST
- Five-Year Follow-Up of Nivolumab in Previously Treated Advanced Non–Small-Cell Lung Cancer: Results From the CA209-003 Study
- (2018) Scott Gettinger et al. JOURNAL OF CLINICAL ONCOLOGY
- Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response
- (2018) Daniel Temko et al. JOURNAL OF PATHOLOGY
- Clinicopathological characteristics of POLE mutation in patients with non-small-cell lung cancer
- (2018) Zhengbo Song et al. LUNG CANCER
- Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1
- (2018) Liang Liu et al. Molecular Cancer
- Tumor Mutational Burden Guides Therapy in a Treatment RefractoryPOLE‐Mutant Uterine Carcinosarcoma
- (2018) Munveer S. Bhangoo et al. ONCOLOGIST
- DNA mismatch repair in cancer
- (2018) Marina Baretti et al. PHARMACOLOGY & THERAPEUTICS
- Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair
- (2018) N. J. Haradhvala et al. Nature Communications
- Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load
- (2018) Hao-Dong Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Novel POLE pathogenic germline variant in a family with multiple primary tumors results in distinct mutational signatures
- (2018) Ester Castellsagué et al. HUMAN MUTATION
- Safety and Antitumor Activity of Pembrolizumab in Advanced Programmed Death Ligand 1–Positive Endometrial Cancer: Results From the KEYNOTE-028 Study
- (2017) Patrick A. Ott et al. JOURNAL OF CLINICAL ONCOLOGY
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Predictive biomarkers for checkpoint inhibitor-based immunotherapy
- (2016) Geoffrey T Gibney et al. LANCET ONCOLOGY
- POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer
- (2015) I. C. van Gool et al. CLINICAL CANCER RESEARCH
- Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer
- (2015) John M. Carethers et al. GASTROENTEROLOGY
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- POLE proofreading mutation, immune response and prognosis in endometrial cancer
- (2015) Inge C. van Gool et al. OncoImmunology
- Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1
- (2015) Brooke E. Howitt et al. JAMA Oncology
- Polymerase ɛ (POLE) mutations in endometrial cancer: Clinical outcomes and implications for Lynch syndrome testing
- (2014) Caroline C. Billingsley et al. CANCER
- A Common Cancer-Associated DNA Polymerase Mutation Causes an Exceptionally Strong Mutator Phenotype, Indicating Fidelity Defects Distinct from Loss of Proofreading
- (2014) D. P. Kane et al. CANCER RESEARCH
- Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer
- (2014) Fadwa A Elsayed et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium
- (2014) Bo Meng et al. GYNECOLOGIC ONCOLOGY
- New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis
- (2014) Laura Valle et al. HUMAN MOLECULAR GENETICS
- A mutation in POLE predisposing to a multi-tumour phenotype
- (2014) ANNA ROHLIN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Frequent POLE1 p.S297F mutation in Chinese patients with ovarian endometrioid carcinoma
- (2014) Yang Zou et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Mutations in POLE and survival of colorectal cancer patients - link to disease stage and treatment
- (2014) Albrecht Stenzinger et al. Cancer Medicine
- DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer
- (2013) David N. Church et al. HUMAN MOLECULAR GENETICS
- Germline and somatic polymerase ϵ and δ mutations define a new class of hypermutated colorectal and endometrial cancers
- (2013) Sarah Briggs et al. JOURNAL OF PATHOLOGY
- Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
- (2012) Claire Palles et al. NATURE GENETICS
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- DNA polymerases and repair synthesis in NER in human cells
- (2011) Alan R. Lehmann DNA REPAIR
- Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer
- (2010) Rintaro Yoshida et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- The high fidelity and unique error signature of human DNA polymerase
- (2010) D. A. Korona et al. NUCLEIC ACIDS RESEARCH
- DNA replication fidelity and cancer
- (2010) Bradley D. Preston et al. SEMINARS IN CANCER BIOLOGY
- DNA polymerase and proofreading suppress discrete mutator and cancer phenotypes in mice
- (2009) T. M. Albertson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA polymerases and human disease
- (2008) Lawrence A. Loeb et al. NATURE REVIEWS GENETICS
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