Regulation of Laboratory-Developed Tests in Preventive Oncology: Emerging Needs and Opportunities

Specificity of the Multi-Target Stool DNA Test for Colorectal Cancer Screening in Average-Risk 45–49 Year-Olds: A Cross-Sectional Study

(2021) Thomas F. Imperiale et al.   Cancer Prevention Research

Liquid biopsy enters the clinic — implementation issues and future challenges

(2021) Michail Ignatiadis et al.   Nature Reviews Clinical Oncology

Minimal Residual Disease Detection using a Plasma-Only Circulating Tumor DNA Assay in Colorectal Cancer Patients

(2021) Aparna R. Parikh et al.   CLINICAL CANCER RESEARCH

Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set

(2021) E.A. Klein et al.   ANNALS OF ONCOLOGY

The PATHFINDER Study: Assessment of the Implementation of an Investigational Multi-Cancer Early Detection Test into Clinical Practice

(2021) Lincoln D. Nadauld et al.   Cancers

The Impact of Direct-to-Consumer Genetic Testing on Patient and Provider

(2020) Mary Beth Palko Dinulos et al.   CLINICS IN LABORATORY MEDICINE

Comment on ‘Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA’ by M. C. Liu et al.

(2020) W.C. Taylor   ANNALS OF ONCOLOGY

Consumer Genomic Testing in 2020

(2020) W. Gregory Feero et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Early assessment of molecular progression and response by whole-genome circulating tumor DNA in advanced solid tumors

(2020) Andrew A. Davis et al.   MOLECULAR CANCER THERAPEUTICS

Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention

(2020) Anne Marie Lennon et al.   SCIENCE

Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA

(2020) M.C. Liu et al.   ANNALS OF ONCOLOGY

A multi-cancer detection test: focus on the positive predictive value

(2020) C. Fiala et al.   ANNALS OF ONCOLOGY

Response to W.C. Taylor, and C. Fiala and E.P. Diamandis

(2020) M.C. Liu et al.   ANNALS OF ONCOLOGY

Benefits and Risks of Direct-to-Consumer Testing

(2020) Nadia Ayala-Lopez et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Clinical and analytical validation of FoundationOne Liquid CDx, a novel 324-Gene cfDNA-based comprehensive genomic profiling assay for cancers of solid tumor origin

(2020) Ryan Woodhouse et al.   PLoS One

The promise of direct-to-consumer COVID-19 testing: ethical and regulatory issues

(2020) Louiza Kalokairinou et al.   Journal of Law and the Biosciences

Clinical Utility of Comprehensive Cell-free DNA Analysis to Identify Genomic Biomarkers in Patients with Newly Diagnosed Metastatic Non–small Cell Lung Cancer

(2019) Natasha B. Leighl et al.   CLINICAL CANCER RESEARCH

Genome-wide cell-free DNA fragmentation in patients with cancer

(2019) Stephen Cristiano et al.   NATURE

Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA

(2019) Nathan Wan et al.   BMC CANCER

Who’s on third? Regulation of third-party genetic interpretation services

(2019) Christi J. Guerrini et al.   GENETICS IN MEDICINE

Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection

(2019) Peter Ulz et al.   Nature Communications

Direct-to-consumer genetic testing

(2019) Rachel Horton et al.   BMJ-British Medical Journal

Direct-to-consumer raw genetic data and third-party interpretation services: more burden than bargain?

(2018) Tia Moscarello et al.   GENETICS IN MEDICINE

False-positive results released by direct-to-consumer genetic tests highlight the importance of clinical confirmation testing for appropriate patient care

(2018) Stephany Tandy-Connor et al.   GENETICS IN MEDICINE

Direct-to-Consumer Testing 2.0: Emerging Models of Direct-to-Consumer Genetic Testing

(2018) Megan A. Allyse et al.   MAYO CLINIC PROCEEDINGS

BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2

(2018) Melissa S. Cline et al.   PLoS Genetics

CAP/ACMG proficiency testing for biochemical genetics laboratories: a summary of performance

(2017) Devin Oglesbee et al.   GENETICS IN MEDICINE

Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing

(2017) Diana Mandelker et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Personal Genomic Testing for Cancer Risk: Results From the Impact of Personal Genomics Study

(2017) Stacy W. Gray et al.   JOURNAL OF CLINICAL ONCOLOGY

Development and Clinical Utility of a Blood-Based Test Service for the Rapid Identification of Actionable Mutations in Non–Small Cell Lung Carcinoma

(2017) Hestia Mellert et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Clinical Variant Classification: A Comparison of Public Databases and a Commercial Testing Laboratory

(2017) William Gradishar et al.   ONCOLOGIST

Current ethical and legal issues in health-related direct-to-consumer genetic testing

(2017) Emilia Niemiec et al.   Personalized Medicine

Direct-to-Consumer Genetic Testing: User Motivations, Decision Making, and Perceived Utility of Results

(2017) J. Scott Roberts et al.   Public Health Genomics

Direct-to-Consumer Genetic Testing

(2017) Brendan Seward   Therapeutic Innovation & Regulatory Science

Consumer use and response to online third-party raw DNA interpretation services

(2017) Catharine Wang et al.   Molecular Genetics & Genomic Medicine

Consumer Perceptions of Interactions With Primary Care Providers After Direct-to-Consumer Personal Genomic Testing

(2016) Cathelijne H. van der Wouden et al.   ANNALS OF INTERNAL MEDICINE

The future of clinical cancer genomics

(2016) Kenneth Offit   SEMINARS IN ONCOLOGY

ClinGen — The Clinical Genome Resource

(2015) Heidi L. Rehm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anchored multiplex PCR for targeted next-generation sequencing

(2014) Zongli Zheng et al.   NATURE MEDICINE

Multitarget Stool DNA Testing for Colorectal-Cancer Screening

(2014) Thomas F. Imperiale et al.   NEW ENGLAND JOURNAL OF MEDICINE