Article
Oncology
Janghee Lee, Jee-Ye Kim, Soong-June Bae, Yeona Cho, Jung-Hwan Ji, Dooreh Kim, Sung-Gwe Ahn, Hyung-Seok Park, Seho Park, Seung-Il Kim, Byeong-Woo Park, Joon Jeong
Summary: The study showed that post-mastectomy radiotherapy (PMRT) can improve locoregional recurrence-free survival and overall survival rates for breast cancer patients who underwent neoadjuvant chemotherapy. However, PMRT may not have an impact on the prognosis of patients who achieved pathologic complete response (pCR) or had minimal residual disease.
Article
Oncology
Anita Mamtani, Varadan Sevilimedu, Tiana Le, Monica Morrow, Andrea Barrio
Summary: The study found that even among patients initially ineligible for breast-conserving surgery, those who became eligible after neoadjuvant chemotherapy had low rates of local recurrence, suggesting that mastectomy may be safely avoided in these patients.
Article
Medicine, General & Internal
Gang Liu, Xiangyi Kong, Qichen Dai, Han Cheng, Jing Wang, Jidong Gao, Yipeng Wang
Summary: This article reports on the clinical characteristics and prognosis of Chinese breast cancer patients, evaluating their overall survival and disease-free survival. The study highlights the importance of personalized treatment strategies and emphasizes the advantages of breast-conserving surgery.
Article
Oncology
Zhanpeng Tang, Xirui Zhu, Yanzhi Li, Chenghao Qu, Lin Li, Shuhai Li, Lei Qi, Ming Lu, Chuanle Cheng, Hui Tian
Summary: This study evaluated the feasibility of implementing ERAS protocols in patients who underwent neoadjuvant chemotherapy before minimally invasive esophagectomy. The results showed no significant difference in postoperative complications, hospital length of stay, and readmission rate between the NACT and non-NACT groups. This indicates that ERAS protocols are safe and feasible for patients who receive neoadjuvant chemotherapy before esophagectomy.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Surgery
Sakiko Yabe, Tsuyoshi Nakagawa, Goshi Oda, Toshiyuki Ishiba, Tomoyuki Aruga, Tomoyuki Fujioka, Mio Mori, Kazunori Kubota, Hiroyuki Uetake
Summary: This study investigated the impact of preoperative sarcopenia on postoperative complications in breast cancer patients who underwent total mastectomy. The results showed that the psoas muscle index is an effective method for diagnosing sarcopenia.
ASIAN JOURNAL OF SURGERY
(2021)
Article
Oncology
Nalee Kim, Won Park, Won Kyung Cho, Hae Young Kim, Doo Ho Choi, Seok Jin Nam, Seok Won Kim, Jeong Eon Lee, Jonghan Yu, Byung Joo Chae, Se Kyung Lee, Jai Min Ryu, Goo-Hyun Mun, Jai-Kyong Pyon, Byung-Joon Jeon
Summary: This study identifies risk factors for ipsilateral breast tumor recurrence (IBTR) following skin-sparing mastectomy (SSM) and nipple-sparing mastectomy (NSM), and suggests that omitting postmastectomy radiation therapy (PMRT) may help improve reconstruction-related complications.
Article
Oncology
So Heun Lee, Dae Wook Hwang, Changhoon Yoo, Kyu-pyo Kim, Sora Kang, Jae Ho Jeong, Dongwook Oh, Tae Jun Song, Sang Soo Lee, Do Hyun Park, Dong Wan Seo, Jin-hong Park, Ki Byung Song, Jae Hoon Lee, Woohyung Lee, Yejong Park, Bong Jun Kwak, Heung-Moon Chang, Baek-Yeol Ryoo, Song Cheol Kim
Summary: This study aimed to evaluate the survival benefit of adjuvant chemotherapy in pancreatic ductal adenocarcinoma (PDAC) patients who underwent surgery following neoadjuvant FOLFIRINOX. The results showed that adjuvant chemotherapy was associated with improved disease-free survival (DFS) and overall survival (OS) compared to observation, which was also confirmed in the propensity score matched (PSM) cohort. However, randomized studies are needed to validate these findings.
CANCER RESEARCH AND TREATMENT
(2023)
Article
Surgery
Dexiang Zhu, Jianguo Xia, Yan Gu, Jianjiang Lin, Kefeng Ding, Bo Zhou, Fei Liang, Tianshu Liu, Chunzhi Qin, Ye Wei, Li Ren, Yunshi Zhong, Jianhua Wang, Zhiping Yan, Jiemin Cheng, Jingwen Chen, Wenju Chang, Shaokang Zhan, Yongbin Ding, Haizhong Huo, Fanlong Liu, Junhui Sun, Xinyu Qin, Jianmin Xu
Summary: The study demonstrated that the addition of preoperative hepatic and regional arterial chemotherapy (PHRAC) could improve disease-free survival (DFS), reduce the incidence of liver metastasis (LM), and enhance overall survival (OS) in patients with stage II and III colorectal cancer (CRC). Furthermore, it did not increase treatment-related morbidity or mortality, indicating that PHRAC is a safe and effective treatment option for these patients.
Article
Oncology
Hiroshi Kurahara, Yuko Mataki, Tetsuya Idichi, Satoshi Iino, Yota Kawasaki, Takaaki Arigami, Shinichiro Mori, Ken Sasaki, Hiroyuki Shinchi, Takao Ohtsuka
Summary: The study suggests that postoperative adjuvant chemotherapy can prolong survival in pancreatic cancer patients who do not respond sufficiently to neoadjuvant therapy.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Haidi Abd El Zaher, Hamada Fathy, Mohamed Abozeid, Mohammed Faisal
Summary: This study reflects on the use of neoadjuvant systemic chemotherapy for women with operable breast cancer. The results show that neoadjuvant chemotherapy can increase the rate of eligibility for breast-conserving surgery, and age and estrogen receptor negativity are associated with this outcome.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Sae Byul Lee, Hakyoung Kim, Jisun Kim, Il Yong Chung, Hee Jeong Kim, Beom Seok Ko, Jong Won Lee, Sei Hyun Ahn, Byung Ho Son
Summary: This study found that performing only SLNB in breast cancer patients with cN positive pathology before neoadjuvant therapy but cN negative pathology after SLNB was associated with lower locoregional recurrence rates. There were significant differences in axillary recurrence and survival rates based on clinical and pathological lymph node status.
Article
Oncology
Yushi Liu, Ye Kang, Jianyi Li, Yang Zhang, Shi Jia, Qiang Sun, Yan Ma, Jing Zhang, Zhenrong Wang, Yanan Cao, Yang Shen
Summary: The study found that NAC may induce cycling intracanceral hypoxia, which is related to NAC response. The changes in ER and claudin-6 before and after NAC will determine the long-term prognosis of patients, with those with stable or increased expression having a better prognosis and those with decreased claudin-6 potentially having a poorer prognosis.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Long Huang, Kang Jia, Kai Yao, Dongliang Liu, Yan Xu, Quanda Liu
Summary: The impact of neoadjuvant chemotherapy (NAC) on survival outcomes in non-muscle-invasive bladder cancer (NMIBC) patients undergoing radical cystectomy (RC) remains unclear. This study found that NAC did not significantly improve overall survival (OS) in NMIBC patients undergoing RC, but showed potential survival advantage in patients with lymph node metastasis.
Article
Oncology
Anna Koralewska, Malgorzata Domagalska-Szopa, Robert Lukowski, Andrzej Szopa
Summary: The use of external breast prosthesis does not significantly affect the postural stability of women after mastectomy. However, excluding visual control during posturographic tests increases postural instability in these women.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Ming-Huei Cheng, Satomi Koide, Courtney Chen, Yi-ling Lin
Summary: The study found that patients with a normal BMI require a smaller flap-used weight but a higher flap-used/flap-harvested percentage for unilateral microsurgical breast reconstructions. The success rate was high with comparable complication and revision rates between normal BMI and overweight groups.
ANNALS OF SURGICAL ONCOLOGY
(2021)