Retinoic Acid Promotes the In Vitro Growth, Patterning and Improves the Cellular Composition of Human Pluripotent Stem-Cell-Derived Intestinal Organoids

Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity

(2021) Samaneh K. Sarvestani et al.   Nature Communications

Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient

(2020) Neil McCarthy et al.   Cell Stem Cell

Retinoic Acid and Lymphotoxin Signaling Promote Differentiation of Human Intestinal M Cells

(2020) Siyuan Ding et al.   GASTROENTEROLOGY

Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells

(2020) Emily M. Holloway et al.   DEVELOPMENTAL CELL

Phenotypic landscape of intestinal organoid regeneration

(2020) Ilya Lukonin et al.   NATURE

Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis

(2018) Scott A. Rankin et al.   DEVELOPMENTAL BIOLOGY

Deriving functional human enteroendocrine cells from pluripotent stem cells

(2018) Katie L. Sinagoga et al.   DEVELOPMENT

Subepithelial telocytes are an important source of Wnts that supports intestinal crypts

(2018) Michal Shoshkes-Carmel et al.   NATURE

Modeling Human Digestive Diseases With CRISPR-Cas9–Modified Organoids

(2018) Masayuki Fujii et al.   GASTROENTEROLOGY

Synthetic hydrogels for human intestinal organoid generation and colonic wound repair

(2017) Ricardo Cruz-Acuña et al.   NATURE CELL BIOLOGY

Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

(2017) Miguel Crespo et al.   NATURE MEDICINE

In vitropatterning of pluripotent stem cell-derived intestine recapitulatesin vivohuman development

(2016) Yu-Hwai Tsai et al.   DEVELOPMENT

Mini-Gut Organoids: Reconstitution of the Stem Cell Niche

(2015) Shoichi Date et al.   Annual Review of Cell and Developmental Biology

Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids

(2015) Mami Matano et al.   NATURE MEDICINE

Mechanisms of retinoic acid signalling and its roles in organ and limb development

(2015) Thomas J. Cunningham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1

(2015) Kaisa Tamminen et al.   PLoS One

A regulatory network controls nephrocan expression and midgut patterning

(2014) J. Hou et al.   DEVELOPMENT

Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon

(2014) Masayoshi Fukuda et al.   GENES & DEVELOPMENT

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids

(2014) Kyle W. McCracken et al.   NATURE

An in vivo model of human small intestine using pluripotent stem cells

(2014) Carey L Watson et al.   NATURE MEDICINE

Transplantation of Expanded Fetal Intestinal Progenitors Contributes to Colon Regeneration after Injury

(2013) Robert P. Fordham et al.   Cell Stem Cell

Brief report: CD24 and CD44 mark human intestinal epithelial cell populations with characteristics of active and facultative stem cells

(2013) Adam D. Gracz et al.   STEM CELLS

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Intestinal Subepithelial Myofibroblasts Support in vitro and in vivo Growth of Human Small Intestinal Epithelium

(2011) Nicholas Lahar et al.   PLoS One

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

(2010) Jason R. Spence et al.   NATURE

The Role of the Visceral Mesoderm in the Development of the Gastrointestinal Tract

(2009) Valérie A. McLin et al.   GASTROENTEROLOGY

Retinoic Acid Signaling Organizes Endodermal Organ Specification along the Entire Antero-Posterior Axis

(2009) Elke Bayha et al.   PLoS One

GATA4 Is Essential for Jejunal Function in Mice

(2008) Michele A. Battle et al.   GASTROENTEROLOGY