Targeted Co-Delivery of Gefitinib and Rapamycin by Aptamer-Modified Nanoparticles Overcomes EGFR-TKI Resistance in NSCLC via Promoting Autophagy
出版年份 2022 全文链接
标题
Targeted Co-Delivery of Gefitinib and Rapamycin by Aptamer-Modified Nanoparticles Overcomes EGFR-TKI Resistance in NSCLC via Promoting Autophagy
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 14, Pages 8025
出版商
MDPI AG
发表日期
2022-07-21
DOI
10.3390/ijms23148025
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Acquired resistance to third-generation EGFR tyrosine kinase inhibitors in patients with de novo EGFRT790M-mutant non–small cell lung cancer
- (2021) Ha-Ram Park et al. Journal of Thoracic Oncology
- Targeting MET in EGFR resistance in non-small-cell lung cancer—ready for daily practice?
- (2020) Sabine Schmid et al. LANCET ONCOLOGY
- LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells
- (2020) Suyeon Kim et al. Autophagy
- A review on progression of epidermal growth factor receptor (EGFR) inhibitors as an efficient approach in cancer targeted therapy
- (2020) Adileh Ayati et al. BIOORGANIC CHEMISTRY
- Hypoxia Induces Resistance to EGFR Inhibitors in Lung Cancer Cells via Upregulation of FGFR1 and the MAPK Pathway
- (2020) Yuhong Lu et al. CANCER RESEARCH
- Ligand decorated chitosan as an advanced nanocarrier for targeted delivery: a critical review
- (2019) Maimoona Qindeel et al. Nanomedicine
- EMT-Mediated Acquired EGFR-TKI Resistance in NSCLC: Mechanisms and Strategies
- (2019) Xuan Zhu et al. Frontiers in Oncology
- EGFR-mediated autophagy in tumourigenesis and therapeutic resistance
- (2019) Min Wu et al. CANCER LETTERS
- Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles
- (2019) Xiaodong Xie et al. Nature Communications
- Tyrosine kinase inhibition of EGFR: a successful history of targeted therapy for NSCLC since 20 years
- (2018) J Vansteenkiste et al. ANNALS OF ONCOLOGY
- Comparative Assay of 2D and 3D Cell Culture Models: Proliferation, Gene Expression and Anticancer Drug Response
- (2018) Aline G. Souza et al. CURRENT PHARMACEUTICAL DESIGN
- Management of acquired resistance to EGFR TKI–targeted therapy in advanced non-small cell lung cancer
- (2018) Shang-Gin Wu et al. Molecular Cancer
- Third generation EGFR TKIs: current data and future directions
- (2018) Chee-Seng Tan et al. Molecular Cancer
- Aptamer-guided nanomedicines for anticancer drug delivery
- (2018) Walhan Alshaer et al. ADVANCED DRUG DELIVERY REVIEWS
- Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress
- (2016) ZHONGLIANG WANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Nanomedicine of synergistic drug combinations for cancer therapy – Strategies and perspectives
- (2016) Rui Xue Zhang et al. JOURNAL OF CONTROLLED RELEASE
- Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors
- (2014) Rasheena Edmondson et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Selective turnover of p62/A170/SQSTM1 by autophagy
- (2014) Yoshinobu Ichimura et al. Autophagy
- Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell-like Properties in Cancer Cells
- (2013) K. Shien et al. CANCER RESEARCH
- EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance
- (2013) Yongjie Wei et al. CELL
- FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR
- (2011) Trever G. Bivona et al. NATURE
- mTOR and cancer: many loops in one pathway
- (2009) Alejo Efeyan et al. CURRENT OPINION IN CELL BIOLOGY
- Somatic EGFR mutations and efficacy of tyrosine kinase inhibitors in NSCLC
- (2009) Helena Linardou et al. Nature Reviews Clinical Oncology
- Chitosan/TPP and Chitosan/TPP-hyaluronic Acid Nanoparticles: Systematic Optimisation of the Preparative Process and Preliminary Biological Evaluation
- (2009) Alessandro Nasti et al. PHARMACEUTICAL RESEARCH
- To Die or Not to Die: That is the Autophagic Question
- (2008) Maria Maiuri et al. CURRENT MOLECULAR MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started