VARS2 Depletion Leads to Activation of the Integrated Stress Response and Disruptions in Mitochondrial Fatty Acid Oxidation

Mitochondrial Aminoacyl-tRNA Synthetase and Disease: The Yeast Contribution for Functional Analysis of Novel Variants

(2021) Sonia Figuccia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Case Report and Review of the Literature: A New and a Recurrent Variant in the VARS2 Gene Are Associated With Isolated Lethal Hypertrophic Cardiomyopathy, Hyperlactatemia, and Pulmonary Hypertension in Early Infancy

(2021) Katarína Kušíková et al.   Frontiers in Pediatrics

Mitochondrial OXPHOS Biogenesis: Co-Regulation of Protein Synthesis, Import, and Assembly Pathways

(2020) Jia Xin Tang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Predicting sustained ventricular arrhythmias in dilated cardiomyopathy: a meta-analysis and systematic review

(2020) Arjan Sammani et al.   ESC Heart Failure

Mitochondrial proteins: from biogenesis to functional networks

(2019) Nikolaus Pfanner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

VARS2-linked mitochondrial encephalopathy: two case reports enlarging the clinical phenotype

(2019) Chiara Begliuomini et al.   BMC Medical Genetics

A combination of two novel VARS2 variants causes a mitochondrial disorder associated with failure to thrive and pulmonary hypertension

(2019) Hui-Lin Chin et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A novel VARS2 gene variant in a patient with epileptic encephalopathy

(2019) Lucija Ruzman et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Clinical, biochemical, and genetic features associated with VARS2 -related mitochondrial disease

(2018) Francesco Bruni et al.   HUMAN MUTATION

The integrated stress response regulates cell health of cardiac progenitors

(2018) George H Searfoss et al.   TOXICOLOGICAL SCIENCES

A novel compound heterozygous mutation in VARS2 in a newborn with mitochondrial cardiomyopathy: a case report of a Chinese family

(2018) Keze Ma et al.   BMC Medical Genetics

A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways

(2018) Thomas Agnew et al.   Cell Reports

Recent Advances in Mitochondrial Aminoacyl-tRNA Synthetases and Disease

(2017) Marie Sissler et al.   TRENDS IN MOLECULAR MEDICINE

New perspective in diagnostics of mitochondrial disorders: two years’ experience with whole-exome sequencing at a national paediatric centre

(2016) Ewa Pronicka et al.   Journal of Translational Medicine

Neonatal encephalocardiomyopathy caused by mutations in VARS2

(2016) Fabian Baertling et al.   METABOLIC BRAIN DISEASE

Association ofVARS2-SFTA2polymorphisms with the risk of chronic hepatitis B in a Korean population

(2015) Hyun Sub Cheong et al.   LIVER INTERNATIONAL

VARS2andTARS2Mutations in Patients with Mitochondrial Encephalomyopathies

(2014) Daria Diodato et al.   HUMAN MUTATION

Use of Whole-Exome Sequencing to Determine the Genetic Basis of Multiple Mitochondrial Respiratory Chain Complex Deficiencies

(2014) Robert W. Taylor et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy

(2013) Benjamin Meder et al.   EUROPEAN HEART JOURNAL

PINCH Proteins Regulate Cardiac Contractility by Modulating Integrin-Linked Kinase-Protein Kinase B Signaling

(2011) B. Meder et al.   MOLECULAR AND CELLULAR BIOLOGY

VARS2 V552V variant as prognostic marker in patients with early breast cancer

(2010) Yee Soo Chae et al.   MEDICAL ONCOLOGY

Aminoacyl-tRNA Synthesis and Translational Quality Control

(2009) Jiqiang Ling et al.   Annual Review of Microbiology

Structure and Organization of Mitochondrial Respiratory Complexes: A New Understanding of an Old Subject

(2009) Giorgio Lenaz et al.   ANTIOXIDANTS & REDOX SIGNALING

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols