Biallelic variants in MOS cause large polar body in oocyte and human female infertility

The Recurrent Mutation in PATL2 Inhibits Its Degradation Thus Causing Female Infertility Characterized by Oocyte Maturation Defect Through Regulation of the Mos-MAPK Pathway

(2021) Qiqi Cao et al.   Frontiers in Cell and Developmental Biology

The comprehensive variant and phenotypic spectrum of TUBB8 in female infertility

(2021) Wei Zheng et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Lysophosphatidic acid improves oocyte quality during IVM by activating the ERK1/2 pathway in cumulus cells and oocytes

(2021) Yerong Ma et al.   MOLECULAR HUMAN REPRODUCTION

Oocyte meiosis-coupled poly(A) polymerase α phosphorylation and activation trigger maternal mRNA translation in mice

(2021) Jun-Chao Jiang et al.   NUCLEIC ACIDS RESEARCH

Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation

(2021) Yin‐Li Zhang et al.   EMBO Molecular Medicine

Bi-allelic mutations in MOS cause female infertility characterized by preimplantation embryonic arrest

(2021) Yang Zeng et al.   HUMAN REPRODUCTION

Bi-allelic Missense Pathogenic Variants in TRIP13Cause Female Infertility Characterized by Oocyte Maturation Arrest

(2020) Zhihua Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Homozygous Mutations in BTG4 Cause Zygotic Cleavage Failure and Female Infertility

(2020) Wei Zheng et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Identification novel mutations in TUBB8 in female infertility and a novel phenotype of large polar body in oocytes with TUBB8 mutations

(2020) Lin Zhao et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans

(2020) Qian-Qian Sha et al.   Nature Communications

A pannexin 1 channelopathy causes human oocyte death

(2019) Qing Sang et al.   Science Translational Medicine

Novel mutations in PATL2: expanding the mutational spectrum and corresponding phenotypic variability associated with female infertility

(2019) Ling Wu et al.   JOURNAL OF HUMAN GENETICS

A story of birth and death: mRNA translation and clearance at the onset of maternal-to-zygotic transition in mammals†

(2019) Qian-Qian Sha et al.   BIOLOGY OF REPRODUCTION

DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development

(2018) Yin‐Li Zhang et al.   EMBO JOURNAL

CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte

(2018) Qian‐Qian Sha et al.   EMBO JOURNAL

Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility

(2017) Wenqiang Liu et al.   HUMAN GENETICS

BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

(2016) Chao Yu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mutations in TUBB8 and Human Oocyte Meiotic Arrest

(2016) Ruizhi Feng et al.   NEW ENGLAND JOURNAL OF MEDICINE

BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

(2016) Chao Yu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tropomodulin-3 is essential in asymmetric division during mouse oocyte maturation

(2016) Yu-Jin Jo et al.   Scientific Reports

Oocyte competency is the key to embryo potential

(2015) David Keefe et al.   FERTILITY AND STERILITY

ERK1/2 Activities Are Dispensable for Oocyte Growth but Are Required for Meiotic Maturation and Pronuclear Formation in Mouse

(2015) Yin-Li Zhang et al.   Journal of Genetics and Genomics

A soft cortex is essential for asymmetric spindle positioning in mouse oocytes

(2013) Agathe Chaigne et al.   NATURE CELL BIOLOGY

Ovarian antral folliculogenesis during the human menstrual cycle: a review

(2011) Angela R. Baerwald et al.   HUMAN REPRODUCTION UPDATE

Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes

(2011) Kexi Yi et al.   NATURE CELL BIOLOGY

Relationship between first polar body morphology before intracytoplasmic sperm injection and fertilization rate, cleavage rate, and embryo quality

(2008) Paula Andrea Navarro et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Across the meiotic divide - CSF activity in the post-Emi2/XErp1 era

(2008) J. Q. Wu et al.   JOURNAL OF CELL SCIENCE