Article
Multidisciplinary Sciences
Ravi Retnakaran, Jiajie Pu, Alexandra Emery, Stewart B. Harris, Sonja M. Reichert, Hertzel C. Gerstein, Natalia McInnes, Caroline K. Kramer, Bernard Zinman
Summary: Induction with short-term insulin therapy followed by maintenance with metformin can stabilize beta-cell function in early type 2 diabetes. The study found that initial reversibility of beta-cell dysfunction and preserved hepatic insulin sensitivity are associated with sustained stabilization of beta-cell function.
NATURE COMMUNICATIONS
(2023)
Article
Endocrinology & Metabolism
Ross Fitzpatrick, Gareth Davison, Jason J. Wilson, Gerard McMahon, Conor McClean
Summary: Exercise has numerous benefits for individuals with type 1 diabetes, but barriers such as post-exercise hypoglycaemia or hyperglycaemia exist. The timing of exercise may be crucial in preventing these blood glucose fluctuations.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Geriatrics & Gerontology
Shangjie Che, Min Meng, Ya Jiang, Xiang Ye, Cuihua Xie
Summary: This study explores the perceptions of exercise and exercise instruction from the perspective of patients with type 2 diabetes mellitus and sarcopenia. The results provide insights into the knowledge-attitudes-practices surrounding exercise, motivators and barriers regarding exercise, and attitudes towards professional exercise instruction. The findings can guide healthcare professionals, patients' families, and policymakers in promoting physical activity among these patients.
Review
Nutrition & Dietetics
Wanbao Yang, Wen Jiang, Shaodong Guo
Summary: This article reviews the effects of different components of macronutrients on insulin sensitivity and their underlying mechanisms, highlighting the importance of adjusting the intake of beneficial food compounds for the prevention of insulin resistance and type 2 diabetes.
Review
Immunology
Zheng Zhou, Bao Sun, Dongsheng Yu, Chunsheng Zhu
Summary: Type 2 diabetes mellitus, a common metabolic disease, is associated with gut microbiota dysbiosis. Remodeling the gut microbiota may be a potential strategy for treating T2DM and its complications.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Medicine, General & Internal
Surapaneni Lakshmi Sravya, Jayshree Swain, Abhay Kumar Sahoo, Swayamsidha Mangaraj, Jayabhanu Kanwar, Pooja Jadhao, Srijit Das
Summary: This study aims to determine the prevalence and predictors of sarcopenia among individuals with type 2 diabetes mellitus (T2DM). The study found that the prevalence of sarcopenia was significantly higher among T2DM individuals compared to non-diabetics. Body mass index, physical activity, serum calcium levels, hypertension, and neuropathy were identified as significant predictors of sarcopenia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Ping Ling, Daizhi Yang, Nan Gu, Xinhua Xiao, Jing Lu, Fang Liu, Zhiguang Zhou, Qin Huang, Jiajun Zhao, Mei Zhang, Ji Hu, Sihui Luo, Jianping Weng, Jinhua Yan, Xueying Zheng
Summary: This study investigated the relationship between CGM metrics and laboratory HbA(1c) in pregnant women with type 1 diabetes. It found a moderate correlation between HbA(1c) and TIR3.5-7.8 during pregnancy. To achieve an HbA(1c) target of less than 6.0%, pregnant women with type 1 diabetes should strive for a TIR3.5-7.8 of greater than 78% during pregnancy.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Multidisciplinary Sciences
Rugang Li, Min He, Qilin Yang, Zezhi Liang, Ying li, Ling Huang, Rong Wu, Jieping Huang
Summary: This study explores the association between baseline serum creatinine level and new-onset type 2 diabetes in the Chinese population. The findings reveal that low serum creatinine is independently associated with an increased risk of type 2 diabetes among Chinese adults, and this association is consistent across different subgroups.
SCIENTIFIC REPORTS
(2023)
Review
Endocrinology & Metabolism
Ruben Fernandez-Rodriguez, Sonia Monedero-Carrasco, Bruno Bizzozero-Peroni, Miriam Garrido-Miguel, Arthur Eumann Mesas, Vicente Martinez-Vizcaino
Summary: This study aimed to determine the effectiveness of resistance exercise on inflammatory biomarkers in patients with type 2 diabetes mellitus (T2DM). Thirteen randomized clinical trials were included, and it was found that resistance exercise can decrease C-reactive protein (CRP) levels and manage systemic inflammation in patients with T2DM. However, the evidence for other inflammatory biomarkers is still inconclusive.
DIABETES & METABOLISM JOURNAL
(2023)
Review
Endocrinology & Metabolism
Baodi Xing, Jie Yu, Huabing Zhang, Yuxiu Li
Summary: Some scholars suggest that RANKL signaling can protect islet beta-cell function and prevent diabetes, while there are also different views that RANKL can improve insulin resistance through inducing beige adipocyte differentiation and increasing energy expenditure. Currently, the results of the regulatory effect on glucose metabolism of RANKL remain conflicting.
THERAPEUTIC ADVANCES IN ENDOCRINOLOGY AND METABOLISM
(2023)
Review
Multidisciplinary Sciences
Banshi Saboo, Jothydev Kesavadev, Arun Shankar, Meera B. Krishna, Shruti Sheth, Vidisha Patel, Gopika Krishnan
Summary: Time-in-range has emerged as a valuable metric for assessing glycemic control in patients with type 2 diabetes, showing potential to identify high-risk individuals and improve diabetes management outcomes.
Review
Nutrition & Dietetics
Anna Izzo, Elena Massimino, Gabriele Riccardi, Giuseppe Della Pepa
Summary: Type 2 diabetes mellitus is a major health burden for the elderly, affecting approximately 25% of those over 65 years old. Sarcopenia, characterized by loss of skeletal muscle mass and function, has been identified as a new complication in elderly individuals with T2DM. It is important for researchers and clinicians to understand the risk factors and associations of sarcopenia in T2DM patients in order to provide appropriate therapeutic interventions.
Article
Public, Environmental & Occupational Health
Azra Ramezankhani, Ali Siamak Habibi-Moeini, Seyed Saeed Tamehri Zadeh, Fereidoun Azizi, Farzad Hadaegh
Summary: This study examined the lifetime risk of type 2 diabetes in Iranian adults, specifically looking at the influence of family history of diabetes and body mass index (BMI). It found that both factors independently increased the risk of diabetes and that the risk was even higher when both factors were present. Additionally, the study found that individuals with a positive family history of diabetes and obesity had a significantly higher risk compared to those with a normal weight and no family history of diabetes.
JOURNAL OF GLOBAL HEALTH
(2022)
Article
Nutrition & Dietetics
Nicholas A. Hulett, Rebecca L. Scalzo, Jane E. B. Reusch
Summary: This review examines the physiological mechanisms of glucose uptake in healthy individuals and individuals with type 2 diabetes, highlighting insulin resistance as a key factor. The review also emphasizes the importance of exercise in enhancing glucose uptake.
Review
Endocrinology & Metabolism
Sha Zhang, Zhan Qi, Yidong Wang, Danfei Song, Deqiu Zhu
Summary: SGLT2 inhibitors have positive effects on weight loss and fat reduction in patients with type 2 diabetes, but they may also cause muscle mass loss and increase the risk of sarcopenia.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Xin Zheng, Yanyan Qi, Lina Bi, Wenli Shi, Yan Zhang, Dan Zhao, Su Hu, Meixin Li, Qin Li
BIOMED RESEARCH INTERNATIONAL
(2020)