Article
Spectroscopy
Mingxin Li, Yu Gao, Yan Zhang, Shuai Gong, Xuechun Tian, Yiqin Yang, Xu Xu, Zhonglong Wang, Shifa Wang
Summary: A highly sensitive fluorescent probe NQBS was designed and synthesized to detect malononitrile, which exhibited selective recognition towards malononitrile among 26 competitive compounds. The sensing mechanism of NQBS towards malononitrile was verified through mass spectrometer, nuclear magnetic resonance, and density functional theory analysis, showing a Knoevenagel condensation process and intramolecular cyclization reaction. The application of NQBS in on-site real-time recognition of malononitrile was successful with the assistance of smartphone and color recognition software.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Applied
Xiuxiu Dai, Zengqiang Liang, Yang Li, Jian Tao, Lingbo Qu, Linping Zhao, Ran Yang
Summary: A self-calibrating fluorescence sensing system was developed for the rapid detection of copper (II) ions in wine. Only yellow fluorescence is selectively quenched by the copper (II) ions, resulting in a change of fluorescence image from yellow to blue. The system showed good linearity with a detection limit of 46.5 nmol/L.
Article
Chemistry, Inorganic & Nuclear
Leyana K. Shaji, Jiya Jose, R. Bhaskar, R. Selva Kumar, V. Vetriarasu, Sarita G. Bhat, S. K. Ashok Kumar
Summary: A new dual fluorescent-colorimetric probe (L) was synthesized for the recognition of bismuth ions (Bi3+). The probe showed visual color change and turn-on emission upon interaction with Bi3+ and demonstrated a promising potential for the detection of Bi3+ ions. The probe's selective color change with Bi3+ was integrated with a smartphone and used for fluorescence imaging in live Human Bone Osteosarcoma cell line (HOS) cells.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Ting Liu, Lixing Fu, Chenhui Yin, Meng Wu, Ligang Chen, Na Niu
Summary: A smartphone platform utilizing ratiometric fluorescence signals was developed for fast, sensitive, and on-site visual detection of silver ions. By constructing a ratiometric fluorescent probe with FITC and CdTe QDs, the color changes of the system were captured on a portable smartphone platform, enabling the visual analysis of Ag+ in environmental water samples at low detection limits.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Haibo Liang, Yongying Li, Bixia Lin, Ying Yu, Yumin Wang, Li Zhang, Yujuan Cao, Manli Guo
Summary: The fabrication of a multicolor fluorescent probe using carbon dots has been achieved in this study, allowing for visual detection of water content through color changes. The probe showed good linear relationship with the water content and low detection limit. The method demonstrated practicality in point-of-care detection of water using naked eye or smartphone.
MICROCHEMICAL JOURNAL
(2022)
Review
Chemistry, Applied
Yao Lu, Guotong Ruan, Wei Du, Jie Li, Naidi Yang, Qiong Wu, Li Lu, Chengwu Zhang, Lin Li
Summary: Iron is the most abundant transition metal ion in the human body, but excessive iron can produce harmful reactive oxygen species that damage cells. Fe2+ plays a crucial role in cellular function and its metabolic abnormalities are associated with various diseases, highlighting the demand for its detection.
Article
Chemistry, Analytical
Yue Wu, Yunshan Zhang, Zhongyuan Xu, Xinyu Guo, Wenjian Yang, Xiaoyu Zhang, Yuheng Liao, Minzhi Fan, Diming Zhang
Summary: In this study, a smartphone-based ratiometric fluorescence probe platform was developed for rapid detection and quantification of calcium ions in blood serum. The low-cost and portable device, coupled with customized software, showed highly reliable measurements of calcium ion concentration in bovine serum. The detection system had a limit of detection of 1.8μM and demonstrated good recoveries and relative standard deviations in real samples.
Article
Chemistry, Applied
Dan Zhang, Sifan Wang, Fangxi Yang, Zicheng Li, Wencai Huang
Summary: In this paper, a hemicyanine-based colorimetric and fluorescent probe Hcy-Py was designed and synthesized for the selective detection of bisulfite. The probe-loaded paper strips showed distinct color changes under both natural light and UV lamp in solutions with different pH values and concentrations of bisulfite. The visual detection of acidic pH and bisulfite in white wine without involving any sophisticated instrument or professional skill was successfully demonstrated.
Article
Chemistry, Analytical
Akshay Silswal, Paersis Weslie, Apurba Lal Koner
Summary: To detect labile iron in lysosomes, we designed and synthesized a multi-component naphthalimide-based fluorescent probe that selectively detects labile iron in the lysosomes. The probe showed high selectivity and sensitivity for Fe(III), with a limit of detection of 0.44 μM, and was able to detect Fenton-type reactions. Additionally, the probe successfully applied for lysosomal imaging and detection of labile Fe(III) in the lysosomal lumen of live cells.
Article
Chemistry, Analytical
Xue Yu, Yunong Huang, Ning Zhang, Qi Zan, Xiaodong Wang, Zhuping Jin, Li Fan, Chuan Dong, Yuewei Zhang
Summary: A LD-targeting and H2S-activated probe with excellent specificity and low toxicity was designed and developed. The probe showed excellent imaging performance in living cells, cancer tissues, and Arabidopsis seedlings, demonstrating potential for cancer diagnosis. Additionally, a smartphone-integrated platform for H2S analysis was successfully established.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Applied
Hui Sun, Qingyu Xu, Chen Xu, Yukun Zhang, Jindong Ai, Mingguang Ren, Keyin Liu, Fangong Kong
Summary: In this study, a rhodamine polymer fluorescent probe (PEG-R) was designed and synthesized, with improved water solubility by the introduction of polyethylene glycol, enhancing its performance and broadening its application in the food field. The PEG-R exhibited high sensitivity, selectivity, and fast response to Cu2+, with a approximately 29-fold fluorescence enhancement and a limit of detection (LOD) of 1.295 x 10-6 M. This probe can be used for determining Cu2+ in living cells, zebrafish, white wine, and food products, and can be made into practical gels and test strips.
Article
Chemistry, Multidisciplinary
Bing Deng, Feng Guo, Ning Duan, Shaoxiang Yang, Hongyu Tian, Baoguo Sun
Summary: A solvatochromic fluorescent probe with D-pi-A molecular configuration was developed, showing excellent polarity sensitivity and different colors based on solvent types. It provided strong support for the rapid determination of solvent polarity and could also be used for alcohol level determination in Baijiu using a smartphone.
Article
Chemistry, Applied
Jie Fang, Xiang Li, Dandan Pi, Chao Gao, Sihao Gao, Wei Li, Wu Yan, Hantao Zou
Summary: A novel conjugated polymer-based ratiometric fluorescent probe PFTQ has been synthesized for the quantitative detection of bisulfite in food samples. The probe can change emission color upon reaction with bisulfite and convert the signal into digital values for accurate measurement. This sensing platform enables fast and accurate detection of bisulfite in various food samples.
Article
Chemistry, Analytical
Xiaoxia Chen, Xingxing Ren, Yuhan Zhu, Ziyan Fan, Lele Zhang, Zhengjie Liu, Ling Dong, Zijuan Hai
Summary: The study focused on the development of two CTB-activated FL/PA probes, demonstrating high sensitivity and spatial resolution in monitoring CTB activity in vivo. HCy-Cit-Val showed superior performance and is envisioned to be suitable for clinical early diagnosis of CTB-related cancer in the near future.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Javier Cisneros-Sureda, Diego Rey-Varela, Jaime Rodriguez, Miguel Balado, Manuel L. Lemos, Carlos Jimenez
Summary: This study reports the design and synthesis of a new fluorescent probe based on amonabactins, which can label Aeromonas bacteria through their specific transport proteins. The probe also has the potential for selective labeling of other Aeromonas species and can be used for detection of Aeromonas in water and fish farming samples.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
