House dust mite‐induced Akt‐ERK1 / 2‐C / EBP beta pathway triggers CCL20 ‐mediated inflammation and epithelial–mesenchymal transition for airway remodeling

Pirfenidone ameliorated AGE-induced EMT and attenuated peritoneal fibrosis in peritoneal mesothelial cells

(2021) Xiao Fenglin et al.   Molecular & Cellular Toxicology

Klotho antagonizes pulmonary fibrosis through suppressing pulmonary fibroblasts activation, migration, and extracellular matrix production: a therapeutic implication for idiopathic pulmonary fibrosis

(2020) Qiqing Huang et al.   Aging-US

NLRP3 Activation Induced by Neutrophil Extracellular Traps Sustains Inflammatory Response in the Diabetic Wound

(2019) Dan Liu et al.   CLINICAL SCIENCE

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation

(2019) Hiroaki Shimizu et al.   Scientific Reports

Pharmacological Inhibitors of the NLRP3 Inflammasome

(2019) Ayesha Zahid et al.   Frontiers in Immunology

Profiling of healthy and asthmatic airway smooth muscle cells following IL-1β treatment: a novel role for CCL20 in chronic mucus hyper-secretion

(2018) Alen Faiz et al.   EUROPEAN RESPIRATORY JOURNAL

House dust mite allergy: Its innate immune response and immunotherapy

(2018) Fang-Liang Huang et al.   IMMUNOBIOLOGY

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

IL-4 Modulates CCL11 and CCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells

(2016) Yoshitaka Hosokawa et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

IL-33 is related to innate immune activation and sensitization to HDM in mild steroid-free asthma

(2016) C. Porsbjerg et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Fluorofenidone attenuates pulmonary inflammation and fibrosisviainhibiting the activation of NALP3 inflammasome and IL-1β/IL-1R1/MyD88/NF-κB pathway

(2016) Cheng Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hyperactivation of the NLRP3 Inflammasome in Myeloid Cells Leads to Severe Organ Damage in Experimental Lupus

(2016) Ailing Lu et al.   JOURNAL OF IMMUNOLOGY

Clusterin Modulates Allergic Airway Inflammation by Attenuating CCL20-Mediated Dendritic Cell Recruitment

(2016) Gyong Hwa Hong et al.   JOURNAL OF IMMUNOLOGY

CCL20 mediates RANK/RANKL-induced epithelial-mesenchymal transition in endometrial cancer cells

(2016) Yao Liu et al.   Oncotarget

Molecular Activation of the NLRP3 Inflammasome in Fibrosis: Common Threads Linking Divergent Fibrogenic Diseases

(2015) Carol M. Artlett et al.   ANTIOXIDANTS & REDOX SIGNALING

Paracrine CCL20 loop induces epithelial-mesenchymal transition in breast epithelial cells

(2015) S. Marsigliante et al.   MOLECULAR CARCINOGENESIS

CCR6 and CCL20: emerging players in the pathogenesis of rheumatoid arthritis

(2014) Adrian YS Lee et al.   IMMUNOLOGY AND CELL BIOLOGY

Transforming growth factor β and severe asthma: A perfect storm

(2014) Mazen Al-Alawi et al.   RESPIRATORY MEDICINE

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

(2012) Jeremy A. Hirota et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Distinct TLR-mediated pathways regulate house dust mite–induced allergic disease in the upper and lower airways

(2012) Ji-Hwan Ryu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

(2012) Christine Juliana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Human Papillomavirus Type 8 Interferes with a Novel C/EBPβ-Mediated Mechanism of Keratinocyte CCL20 Chemokine Expression and Langerhans Cell Migration

(2012) Tanya Sperling et al.   PLoS Pathogens

NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant

(2011) A.-G. Besnard et al.   ALLERGY

Epithelial cells and airway diseases

(2011) David Proud et al.   IMMUNOLOGICAL REVIEWS

Role of Transforming Growth Factor–β in Airway Remodeling in Asthma

(2010) Rabih Halwani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Recruitment of CCR6-Expressing Th17 Cells by CCL 20 Secreted from IL-1β-, TNF-α-, and IL-17A-Stimulated Endometriotic Stromal Cells

(2010) Tetsuya Hirata et al.   ENDOCRINOLOGY

CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC

(2010) Lara E. Kallal et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

House Dust Mite–Promoted Epithelial-to-Mesenchymal Transition in Human Bronchial Epithelium

(2009) Irene H. Heijink et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Innate immune responses of airway epithelium to house dust mite are mediated through β-glucan–dependent pathways

(2009) Amy T. Nathan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dectin-1 is Inducible and Plays an Essential Role for Mycobacteria-Induced Innate Immune Responses in Airway Epithelial Cells

(2009) Hye-Mi Lee et al.   JOURNAL OF CLINICAL IMMUNOLOGY

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE