Article
Neurosciences
Sashrika Pillay, Adhil Bhagwandin, Mads F. Bertelsen, Nina Patzke, Gerhard Engler, Andreas K. Engel, Paul R. Manger
Summary: This study provides an analysis of the cytoarchitecture, myeloarchitecture, and chemoarchitecture of the diencephalon in the banded mongoose and domestic ferret, showing strong similarities in nuclear organization and minor variations in the density of certain structures expressing calcium-binding proteins. Despite shared ancestry, phylogenetic constraints limit adaptive evolutionary plasticity within carnivores, with the most notable difference being the physical inversion of certain nuclei in the domestic ferret compared to other carnivores.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Neurosciences
Jordan Swiegers, Adhil Bhagwandin, Busisiwe C. Maseko, Chet C. Sherwood, Therese Hard, Mads F. Bertelsen, Muhammad A. Spocter, Zoltan Molnar, Paul R. Manger
Summary: In this study, the number, distribution, and neurochemical identities of infracortical white matter neurons were examined in three primate species. The density of WMICs varies across brain regions, with some WMICs containing specific markers like nNOS and calretinin. Squirrel monkeys and crested macaques may serve as valuable animal models for studying WMICs in neurodegenerative and psychiatric disorders in humans.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Neurosciences
Sashrika Pillay, Adhil Bhagwandin, Mads F. Bertelsen, Nina Patzke, Gerhard Engler, Andreas K. Engel, Paul R. Manger
Summary: This study compared the cytoarchitecture, myeloarchitecture, and chemoarchitecture of the amygdaloid body in banded mongooses and domestic ferrets. The results showed that while there were many similarities between the two species, there were also differences, such as the presence of a cortex-amygdala transition zone in the domestic ferret and variances in neuron densities expressing calcium-binding proteins. Despite these differences, certain aspects of chemoarchitecture, such as cholinergic innervation and specific neuron markers, appear to be consistent features of the mammalian amygdala.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Neurosciences
Jordan Swiegers, Adhil Bhagwandin, Victoria M. Williams, Busisiwe C. Maseko, Chet C. Sherwood, Therese Hard, Mads F. Bertelsen, Kathleen S. Rockland, Zoltan Molnar, Paul R. Manger
Summary: In this study, the number, distribution, and immunoreactivity of infracortical white matter neuronal population in the brain of an adult female chimpanzee were investigated. Different subpopulations of WMICs were identified, with approximately 22.6% of them containing nNOS, CR, and PV immunopositivity. Insights from these findings are crucial for understanding cognitive conditions and the evolution of these cell types in the human brain.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Review
Biology
Ivaylo Borislavov Iotchev, Eniko Kubinyi
Summary: Sleep spindles are rhythmic events observed in non-REM sleep and play a crucial role in memory consolidation, sleep quality, mental health, and aging. Advancements in understanding their mechanisms have not diminished the importance of animal models which can still provide valuable insights, especially in researching cognitive aging and exploring the evolutionary history of sleep spindles. Emphasizing the cognitive aging aspect may shape future comparative studies on sleep spindles, and stricter validation criteria can help confirm shared features of sleep spindles across species.
BIOLOGICAL REVIEWS
(2021)
Review
Biology
Ruben Rial, Francesca Canellas, Mourad Akaarir, Jose A. Rubino, Pere Barcelo, Aida Martin, Antoni Gamundi, M. Cristina Nicolau
Summary: Mammals evolved from reptiles due to an evolutionary bottleneck, and the origin of mammalian sleep can be traced back to the need to protect against diurnal light by resting in lightproof burrows. The extinction of dinosaurs allowed some early mammals to return to diurnal activity and led to the high variability in sleep patterns observed today.
Article
Biochemistry & Molecular Biology
Kaya von Eugen, Heike Endepols, Alexander Drzezga, Bernd Neumaier, Onur Gunturkun, Heiko Backes, Felix Strockens
Summary: Birds are able to efficiently utilize glucose, allowing them to have a higher number of neurons without incurring additional metabolic costs. This advantage may have emerged during the evolution of avian brains.
Article
Neurosciences
Paul R. Manger, Oxana Eschenko
Summary: The nuclear parcellation of the locus coeruleus complex has been described in approximately 80 mammal species, revealing significant variations in noradrenergic neuron organization across species. Understanding these differences is crucial for translating findings from laboratory rodents to humans.
Review
Behavioral Sciences
Andrew C. Halley
Summary: This study investigates the variation in embryonic development pace in mammals and finds differences among different species. The pace of development is strongly associated with phenotypic characteristics in adults.
BRAIN BEHAVIOR AND EVOLUTION
(2022)
Article
Neurosciences
Samson Chengetanai, Adhil Bhagwandin, Mads F. Bertelsen, Therese Hard, Patrick R. Hof, Muhammad A. Spocter, Paul R. Manger
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Samson Chengetanai, Adhil Bhagwandin, Mads F. Bertelsen, Therese Hard, Patrick R. Hof, Muhammad A. Spocter, Paul R. Manger
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Jagmeet S. Grewal, Tyler Gloe, Joseph Hegedus, Kathleen Bitterman, Brendon K. Billings, Samson Chengetanai, Sarah Bentil, Victoria X. Wang, Johnny C. Ng, Cheuk Y. Tang, Simon Geletta, Bridget Wicinski, Mads Bertelson, Benjamin C. Tendler, Rogier B. Mars, Geoffrey K. Aguirre, Clare Rusbridge, Patrick R. Hof, Chet C. Sherwood, Paul R. Manger, Muhammad A. Spocter
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Samson Chengetanai, Jonathan D. Tenley, Mads F. Bertelsen, Therese Hard, Adhil Bhagwandin, Mark Haagensen, Cheuk Y. Tang, Victoria X. Wang, Bridget Wicinski, Patrick R. Hof, Paul R. Manger, Muhammad A. Spocter
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Samson Chengetanai, Adhil Bhagwandin, Mads F. Bertelsen, Therese Hard, Patrick R. Hof, Muhammad A. Spocter, Paul R. Manger
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Sashrika Pillay, Adhil Bhagwandin, Mads F. Bertelsen, Nina Patzke, Gerhard Engler, Andreas K. Engel, Paul R. Manger
Summary: This study provides an analysis of the cytoarchitecture, myeloarchitecture, and chemoarchitecture of the diencephalon in the banded mongoose and domestic ferret, showing strong similarities in nuclear organization and minor variations in the density of certain structures expressing calcium-binding proteins. Despite shared ancestry, phylogenetic constraints limit adaptive evolutionary plasticity within carnivores, with the most notable difference being the physical inversion of certain nuclei in the domestic ferret compared to other carnivores.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Neurosciences
Sashrika Pillay, Adhil Bhagwandin, Mads F. Bertelsen, Nina Patzke, Gerhard Engler, Andreas K. Engel, Paul R. Manger
Summary: The study compared the hippocampal formation of two carnivoran species, the banded mongoose and domestic ferret, using staining techniques. Despite differences, both species showed similarities in major hippocampal structures and similar rates of adult hippocampal neurogenesis. However, subtle variations in chemoarchitecture were also observed between the two species.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Neurosciences
Sashrika Pillay, Adhil Bhagwandin, Mads F. Bertelsen, Nina Patzke, Gerhard Engler, Andreas K. Engel, Paul R. Manger
Summary: This study compared the cytoarchitecture, myeloarchitecture, and chemoarchitecture of the amygdaloid body in banded mongooses and domestic ferrets. The results showed that while there were many similarities between the two species, there were also differences, such as the presence of a cortex-amygdala transition zone in the domestic ferret and variances in neuron densities expressing calcium-binding proteins. Despite these differences, certain aspects of chemoarchitecture, such as cholinergic innervation and specific neuron markers, appear to be consistent features of the mammalian amygdala.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Multidisciplinary Sciences
Paul R. Manger, Nina Patzke, Muhammad A. Spocter, Adhil Bhagwandin, Karl A. E. Karlsson, Mads F. Bertelsen, Abdulaziz N. Alagaili, Nigel C. Bennett, Osama B. Mohammed, Suzana Herculano-Houzel, Patrick R. Hof, Kjell Fuxe
Summary: By comparing cetacean brains with artiodactyl brains, it was found that cetacean brains show enhanced thermogenetic functionality, possibly related to their aquatic niche.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Jordan Swiegers, Adhil Bhagwandin, Busisiwe C. Maseko, Chet C. Sherwood, Therese Hard, Mads F. Bertelsen, Muhammad A. Spocter, Zoltan Molnar, Paul R. Manger
Summary: In this study, the number, distribution, and neurochemical identities of infracortical white matter neurons were examined in three primate species. The density of WMICs varies across brain regions, with some WMICs containing specific markers like nNOS and calretinin. Squirrel monkeys and crested macaques may serve as valuable animal models for studying WMICs in neurodegenerative and psychiatric disorders in humans.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Anthropology
Manisha R. Dayal, Brendon K. Billings, Desire Brits, Abdallah Abdallah, Muhammad A. Spocter, Mubarak A. Bidmos
Summary: This study investigates the use of the foramen magnum region in the cranial base for sex estimation in Black South Africans during forensic analyses. The average accuracies obtained through discriminant function analyses ranged from 60-71%, indicating a lower accuracy compared to other skeletal elements. Therefore, caution should be exercised when using the equations provided in this study, and only in the absence of more accurate elements.
ANTHROPOLOGISCHER ANZEIGER
(2022)
Article
Behavioral Sciences
[Anonymous]
Summary: The 2022 meetings of the J.B. Johnston Club for Evolutionary Neuroscience and Karger Workshop in Evolutionary Neuroscience will be held in San Diego, California, USA, focusing on the concept and forces behind the evolution of the nervous system. The meetings consist of the Karger Workshop and the JBJC meeting, organized by different parties.
BRAIN BEHAVIOR AND EVOLUTION
(2022)
Article
Neurosciences
Demi Oddes, Ayanda Ngwenya, Illke B. Malungo, Anita Burkevica, Therese Hard, Mads F. Bertelsen, Muhammad A. Spocter, D. Michael Scantlebury, Paul R. Manger
Summary: Using orexin-A immunohistochemistry, the distribution, morphology, and nuclear parcellation of orexinergic neurons in the hypothalami of Asiatic lions, African lions, and Southeast African cheetahs were studied. The clustering and distribution of orexinergic neurons in these felids appear to be more complex than in other mammals.
JOURNAL OF COMPARATIVE NEUROLOGY
(2023)
Review
Medicine, General & Internal
Olivia C. Matz, Muhammad Spocter
Summary: Huntington's disease is an autosomal dominant genetic disorder characterized by the degeneration of basal nuclei, causing symptoms such as impaired voluntary movement, cognitive decline, and psychiatric disorders. The accumulation of Huntingtin protein in the striatum leads to the destruction of medium spiny neurons. Currently, there is no cure for Huntington's disease, but there are symptomatic treatments available for chorea and psychiatric conditions.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)