Generation of a homozygous mutant drug transporter (ABCB1) knockout line in the sea urchin Lytechinus pictus

Early patterning of ABCB, ABCC, and ABCG transporters establishes unique territories of small molecule transport in the embryonic mesoderm and endoderm.

(2021) Catherine S. Schrankel et al.   DEVELOPMENTAL BIOLOGY

CRISPR/Cas9 mutagenesis reveals a role for ABCB1 in gut immune responses to Vibrio diazotrophicus in sea urchin larvae

(2021) Travis J. Fleming et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Chromosomal-Level Genome Assembly of the Painted Sea Urchin Lytechinus pictus: A Genetically Enabled Model System for Cell Biology and Embryonic Development

(2021) Jacob F Warner et al.   Genome Biology and Evolution

Engineering large-scale chromosomal deletions by CRISPR-Cas9

(2021) Thomas F Eleveld et al.   NUCLEIC ACIDS RESEARCH

The nanoscale organization of the Wnt signaling integrator Dishevelled in the vegetal cortex domain of an egg and early embryo

(2021) John H. Henson et al.   PLoS One

Bindin is essential for fertilization in the sea urchin

(2021) Gary M. Wessel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How to turn an organism into a model organism in 10 ‘easy’ steps

(2020) Benjamin J. Matthews et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Establishment of homozygous knock-out sea urchins

(2020) Shunsuke Yaguchi et al.   CURRENT BIOLOGY

Embryo, larval, and juvenile staging of Lytechinus pictus from fertilization through sexual maturation.

(2020) Katherine T. Nesbit et al.   DEVELOPMENTAL DYNAMICS

Establishment of knockout adult sea urchins by using a CRISPR‐Cas9 system

(2019) Daming Liu et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Sea urchin reproductive performance in a changing ocean: poor males improve while good males worsen in response to ocean acidification

(2019) Kathryn E. Smith et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

An update on expression and function of p-gp/abcb1 and bcrp/abcg2 in the placenta and fetus

(2018) Lyrialle W. Han et al.   Expert Opinion on Drug Metabolism & Toxicology

ABC Transporters in Cancer Stem Cells: Beyond Chemoresistance

(2017) Romana-Rea Begicevic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clustal Omega for making accurate alignments of many protein sequences

(2017) Fabian Sievers et al.   PROTEIN SCIENCE

P-glycoprotein multidrug transporter in inflammatory bowel diseases: More questions than answers

(2017) Elke Cario   WORLD JOURNAL OF GASTROENTEROLOGY

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome

(2017) Ha Youn Shin et al.   Nature Communications

Functional diversification of sea urchin ABCC1 (MRP1) by alternative splicing

(2016) Tufan Gökirmak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Genome editing in sea urchin embryos by using a CRISPR/Cas9 system

(2016) Che-Yi Lin et al.   DEVELOPMENTAL BIOLOGY

CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering

(2016) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

ABCC5 is required for cAMP-mediated hindgut invagination in sea urchin embryos

(2015) Lauren E. Shipp et al.   DEVELOPMENT

Copper Oxide and Zinc Oxide Nanomaterials Act as Inhibitors of Multidrug Resistance Transport in Sea Urchin Embryos: Their Role as Chemosensitizers

(2015) Bing Wu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A RESTful API for Access to Phylogenetic Tools via the CIPRES Science Gateway

(2015) Mark A. Miller et al.   Evolutionary Bioinformatics

The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides

(2015) Konstantinos D. Tsirigos et al.   NUCLEIC ACIDS RESEARCH

Dual sgRNAs facilitate CRISPR/Cas9-mediated mouse genome targeting

(2014) Jiankui Zhou et al.   FEBS Journal

Transport in technicolor: Mapping ATP-binding cassette transporters in sea urchin embryos

(2014) Tufan Gökirmak et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

ATP-binding cassette (ABC) transporter expression and localization in sea urchin development

(2012) Lauren E. Shipp et al.   DEVELOPMENTAL DYNAMICS

Localization and Substrate Selectivity of Sea Urchin Multidrug (MDR) Efflux Transporters

(2012) Tufan Gökirmak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology