EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules

Lysate-based pipeline to characterize microtubule-associated proteins uncovers unique microtubule behaviours

(2022) A. S. Jijumon et al.   NATURE CELL BIOLOGY

Posttranslational modification of microtubules by the MATCAP detyrosinase

(2022) Lisa Landskron et al.   SCIENCE

Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin

(2021) Takashi Hotta et al.   CURRENT BIOLOGY

α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics

(2021) Jiayi Chen et al.   DEVELOPMENTAL CELL

The Tubulin Code in Microtubule Dynamics and Information Encoding

(2020) Antonina Roll-Mecak   DEVELOPMENTAL CELL

Philosopher: a versatile toolkit for shotgun proteomics data analysis

(2020) Felipe da Veiga Leprevost et al.   NATURE METHODS

WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System

(2020) Yeonjoo Kim et al.   Endocrinology and Metabolism

Spastin is a dual-function enzyme that severs microtubules and promotes their regrowth to increase the number and mass of microtubules

(2019) Yin-Wei Kuo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression

(2019) Rozita Adib et al.   Science Signaling

Multivalent electrostatic microtubule interactions of synthetic peptides are sufficient to mimic advanced MAP-like behavior

(2019) Hauke Drechsler et al.   MOLECULAR BIOLOGY OF THE CELL

EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms

(2018) Weston Stauffer et al.   Scientific Reports

Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome–autophagosome fusion

(2018) Nitin Mohan et al.   JOURNAL OF CELL BIOLOGY

MSFragger: ultrafast and comprehensive peptide identification in mass spectrometry–based proteomics

(2017) Andy T Kong et al.   NATURE METHODS

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy

(2017) Meghna Kannan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

(2017) Chrystelle Aillaud et al.   SCIENCE

Vasohibins encode tubulin detyrosinating activity

(2017) Joppe Nieuwenhuis et al.   SCIENCE

Kinesin-4 KIF21B is a potent microtubule pausing factor

(2017) Wilhelmina E van Riel et al.   eLife

Directional cell expansion requires NIMA-related kinase 6 (NEK6)-mediated cortical microtubule destabilization

(2017) Shogo Takatani et al.   Scientific Reports

EML proteins in microtubule regulation and human disease

(2016) Andrew M. Fry et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Affinity purification and characterization of functional tubulin from cell suspension cultures of Arabidopsis and tobacco

(2016) Takashi Hotta et al.   PLANT PHYSIOLOGY

Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes

(2016) P. Robison et al.   SCIENCE

Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain

(2015) Mark W. Richards et al.   BIOCHEMICAL JOURNAL

Microtubule detyrosination guides chromosomes during mitosis

(2015) M. Barisic et al.   SCIENCE

Kinetochore-microtubule stability governs the metaphase requirement for Eg5

(2014) A. Sophia Gayek et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical  -propeller domain

(2014) M. W. Richards et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PA tag: A versatile protein tagging system using a super high affinity antibody against a dodecapeptide derived from human podoplanin

(2014) Yuki Fujii et al.   PROTEIN EXPRESSION AND PURIFICATION

Kinesin-12 Differentially Affects Spindle Assembly Depending on Its Microtubule Substrate

(2013) Emma G. Sturgill et al.   CURRENT BIOLOGY

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The Kinetochore-Bound Ska1 Complex Tracks Depolymerizing Microtubules and Binds to Curved Protofilaments

(2012) Jens C. Schmidt et al.   DEVELOPMENTAL CELL

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development

(2012) Chelsea B. Backer et al.   MOLECULAR BIOLOGY OF THE CELL

One-step purification of assembly-competent tubulin from diverse eukaryotic sources

(2012) Per O. Widlund et al.   MOLECULAR BIOLOGY OF THE CELL

LRRK2 Parkinson disease mutations enhance its microtubule association

(2011) Lauren R. Kett et al.   HUMAN MOLECULAR GENETICS

Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells

(2011) P. Khandelia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Kinesin-8 Kif18A Dampens Microtubule Plus-End Dynamics

(2010) Yaqing Du et al.   CURRENT BIOLOGY

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

(2010) Benjamin Lacroix et al.   JOURNAL OF CELL BIOLOGY

Motor-dependent microtubule disassembly driven by tubulin tyrosination

(2009) Leticia Peris et al.   JOURNAL OF CELL BIOLOGY

Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells

(2009) Paul M. Miller et al.   NATURE CELL BIOLOGY

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

(2009) Yoshiyuki Konishi et al.   NATURE NEUROSCIENCE

Single Molecule Imaging Reveals Differences in Microtubule Track Selection Between Kinesin Motors

(2009) Dawen Cai et al.   PLOS BIOLOGY

Arabidopsis SPIRAL2 promotes uninterrupted microtubule growth by suppressing the pause state of microtubule dynamics

(2008) M. Yao et al.   JOURNAL OF CELL SCIENCE

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells

(2008) S. Dunn et al.   JOURNAL OF CELL SCIENCE

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

(2008) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Capturing protein tails by CAP-Gly domains

(2008) Michel O. Steinmetz et al.   TRENDS IN BIOCHEMICAL SCIENCES