Elucidation of partial activation of cannabinoid receptor type 2 and identification of potential partial agonists: Molecular dynamics simulation and structure-based virtual screening

Activation Mechanism of Corticotrophin Releasing Factor Receptor Type 1 Elucidated Using Molecular Dynamics Simulations

(2021) Abdullahi Ibrahim Uba et al.   ACS Chemical Neuroscience

Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures

(2020) Tian Hua et al.   CELL

Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex

(2020) Changrui Xing et al.   CELL

Binding of agonist WAY-267,464 and antagonist WAY-methylated to oxytocin receptor probed by all-atom molecular dynamics simulations

(2020) Abdullahi Ibrahim Uba et al.   LIFE SCIENCES

Cannabinoids and Cannabinoid Receptors: The Story so Far

(2020) Fred Shahbazi et al.   iScience

Crystal Structure of the Human Cannabinoid Receptor CB2

(2019) Xiaoting Li et al.   CELL

Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol

(2019) Pasquale Linciano et al.   JOURNAL OF NATURAL PRODUCTS

Common activation mechanism of class A GPCRs

(2019) Qingtong Zhou et al.   eLife

The Molecular Basis of G Protein–Coupled Receptor Activation

(2018) William I. Weis et al.   Annual Review of Biochemistry

An overview of the cannabinoid type 2 receptor system and its therapeutic potential

(2018) Bihua Bie et al.   Current Opinion in Anesthesiology

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

(2017) Marjolein Soethoudt et al.   Nature Communications

Editorial: The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation

(2017) Marialessandra Contino et al.   Frontiers in Neuroscience

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

(2016) Partha Mukhopadhyay et al.   BRITISH JOURNAL OF PHARMACOLOGY

The CB2 receptor and its role as a regulator of inflammation

(2016) Caroline Turcotte et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins

(2015) Edward Harder et al.   Journal of Chemical Theory and Computation

Chemistry: Chemical con artists foil drug discovery

(2014) Jonathan Baell et al.   NATURE

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

NetworkView: 3D display and analysis of protein{middle dot}RNA interaction networks

(2012) J. Eargle et al.   BIOINFORMATICS

The effects of Δ9-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation andin vitromotility disturbances in rat colitis

(2010) JM Jamontt et al.   BRITISH JOURNAL OF PHARMACOLOGY

MILCH SHAKE: An efficient method for constraint dynamics applied to alkanes

(2009) A. G. Bailey et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Cannabinoid CB1 and CB2 Receptor Ligand Specificity and the Development of CB2-Selective Agonists

(2008) John Ashton et al.   CURRENT MEDICINAL CHEMISTRY

The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

(2007) R G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY