期刊
CARBOHYDRATE POLYMERS
卷 290, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2022.119490
关键词
Chitosan modification; Ionized chitosan; Structure analysis; Antibacterial activity
资金
- National Key R&D Program of China [2018YFD0400600]
- National Undergraduate Training Program on Innovation and Entrepreneurship [202110353025]
In this study, ionized chitosan (ICS) was successfully synthesized from chitosan through methylation and sulfonation reactions. The modified ICS showed improved water solubility and antibacterial activity, indicating its potential as a water-soluble antibacterial agent.
In order to improve the solubility and antibacterial activity of chitosan and expand its application range, ionized chitosan (ICS) was successfully synthesized from chitosan through methylation and sulfonation reactions in this study. The chemical structures of the polymers were verified by Fourier transform infrared spectroscopy (FTIR) and 1H NMR, and a series of characterizations of the polymer were carried out by analytical methods such as element analysis (EA), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and X-ray diffraction (XRD). The results showed that the water solubility of the modified ICS was significantly improved. The introduction of propyl sulfonic acid groups with particle size decreasing and potential increasing greatly improved the antibacterial activity of chitosan, indicating that the ICS had the potential as a water-soluble antibacterial agent.
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