Phase 1 Randomized, Double-Blind, Placebo-Controlled Study to Determine the Safety, Tolerability, and Pharmacokinetics of a Single Escalating Dose and Repeated Doses of CN-105 in Healthy Adult Subjects

An apoE-derived mimic peptide, COG1410, alleviates early brain injury via reducing apoptosis and neuroinflammation in a mouse model of subarachnoid hemorrhage

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Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage

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Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

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ApoE mimetic ameliorates motor deficit and tissue damage in rat spinal cord injury

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Neuroinflammation after intracerebral hemorrhage

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Post-ischemic inflammation regulates neural damage and protection

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Translational Research in Acute Central Nervous System Injury

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Surveillance neuroimaging and neurologic examinations affect care for intracerebral hemorrhage

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Surgical Trials in Intracerebral Hemorrhage

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ApolipoproteinE mimetic peptides improve outcome after focal ischemia

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The Epidemiology of Intracerebral Hemorrhage in the United States from 1979 to 2008

(2012) Fred Rincon et al.   Neurocritical Care

Apolipoprotein E and Peptide Mimetics Modulate Inflammation by Binding the SET Protein and Activating Protein Phosphatase 2A

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The apoE-mimetic Peptide, COG1410, Improves Functional Recovery in a Murine Model of Intracerebral Hemorrhage

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COG1410 Improves Cognitive Performance and Reduces Cortical Neuronal Loss in the Traumatically Injured Brain

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COG1410, a novel apolipoprotein-E mimetic, improves functional and morphological recovery in a rat model of focal brain ischemia

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N-methyl-d-aspartate receptor inhibition by an apolipoprotein E-derived peptide relies on low-density lipoprotein receptor-associated protein

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Pharmacogenomic Effects of Apolipoprotein E on Intracerebral Hemorrhage

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